1
Peter C Cheeseman: Method for sequencing polynucleotides. Beckman Instruments, William H May, P R Harder, Janis C Henry, April 12, 1994: US05302509 (453 worldwide citation)

A method is provided for determining the sequence of nucleotides on a single strand DNA molecule. The single strand DNA molecule is attached to a leader oligonucleotide and its complementary strand to a solid state support. Fluorescently-labeled 3'-blocked nucleotide triphosphates, with each of the ...


2
Wing S Pang, Mark Gross, Hendra Tanumihardja, Ruediger F Rauskolb, G Andrea Pedrazzini, Santiago F Allen: Automated sample processing system including automatic centrifuge device. Beckman Coulter, William H May, Margaret A Sheldon & Mak Kivinski, May 9, 2000: US06060022 (185 worldwide citation)

A system for a clinical lab that is capable of automatically processing, including sorting, of multiple specimen containers. The system comprises a central controller, a workstation, one or more analyzers, and an automated centrifuge. The workstation has automatic detectors for detecting the presenc ...


3
Robert S Matson, Peter J Coassin, Jang B Rampal, Edwin M Southern: Method and apparatus for creating biopolymer arrays on a solid support surface. Beckman Instruments, William H May, P R Harder, Janis C Henry, July 4, 1995: US05429807 (181 worldwide citation)

An automated method and apparatus for performing biopolymer synthesis on a two-dimensional support surface whereby a two-dimensional matrix or array of biopolymers are obtained on the surface. An applicator in the form of a thick plate having in a surface at least one cavity in the form of an open c ...


4
Dale R Pfost, Torleif O Bjornson, Robert M Coppock, Carl Kowalski, Samuel A Marquiss, Donald S Murray, R Fred Pfost, Brian Sanford, Katherine L Puckett: Automated multi-purpose analytical chemistry processing center and laboratory work station. Beckman Instruments, William H May, Paul R Harder, April 14, 1992: US05104621 (177 worldwide citation)

An automated multi-purpose analytical chemistry processing center and laboratory work station having a movable table for supporting microtiter plates and other fluid receptacles, a movable arm, and a modular mobile pod affixed for reciprocal movement along the arm. The workstation combines into a si ...


5
John E Lillig, Michael J Whelan, Thomas V Cheon, Patricia A Sisson, Orlando Flores: Modular analyzer system. Beckman Instruments, William H May, Arnold Grant, Gary T Hampson, October 23, 1990: US04965049 (165 worldwide citation)

A system of modular analyzers each adapted for independent operation and each possessing different operational characteristics adapted for particular applications. Such modular analyzers may be joined together with precise indexing means such that a single sample carousel may be accessed by fluid tr ...


6
Michael L Bell, Jack D McNeal: Minimally invasive methods for measuring analtes in vivo. Beckman Coulter, William H May, Arnold Grant, Sheldon & Mak, April 2, 2002: US06366793 (160 worldwide citation)

Minimally invasive methods for measuring an analyte, such as glucose, contained in tile interstitial fluid of a body are provided. The methods include the steps of.


7
Chan S Oh: Microfluidic electrophoresis device. Beckman Instruments, William H May, P R Sheldon & Mak Harder, May 18, 1999: US05904824 (140 worldwide citation)

A microfluidic device having opposed spaced apart sheets of siliceous material, such as glass, the opposed facing sides of each of the sheets having hydrophilic and hydrophobic areas which form therebetween a fluid capillary which is hydrophilic and bounded by hydrophobic areas to form an microfluid ...


8
Frank L Waska, Gerald L Klein, Wayne S Johnson: Capillary electrophoresis detection. Beckman Instruments, William H May, Gary T Hampson, Charles Berman, May 17, 1994: US05312535 (104 worldwide citation)

Detecting light in a capillary electrophoresis optical system includes input and output windows in the outside surface of a capillary tube. The width of the windows is not substantially greater than the bore of the tube. A fiber optic input is spaced from the capillary tube so that the light is dire ...


9
Richard P Watts, David L Goodale, Dang M Ngo, Songai Tu, Michael Tran, Michael L Bell: Automatic chemistry analyzer. Beckman Instruments, William H May, P R Sheldon & Mak Harder, September 15, 1998: US05807523 (99 worldwide citation)

An automatic chemistry analyzer is provided having a high throughput and a high reliability. The analyzer uses nephelometric and turbimetric analyzers to analyze a wide variety of parameters within liquid samples typically generated in, for example, a large medical testing laboratory. The machine em ...


10
Howard M Chandler: Barrier-controlled assay device. SmithKline Diagnostics, William H May, Gary T Hampson, March 4, 1997: US05607863 (92 worldwide citation)

An assay device for detection and/or determination of an analyte in a test sample uses a barrier containing an aperture to control the application of reagents to the device for greater reproducibility of results. In its simplest form, the device comprises: (1) a chromatographic medium having a first ...