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Hans Joachim Burkardt, Wilhelm Weber: Transport system for shipping microbiological samples. Hoffmann La Roche, George M Gould, William H Epstein, John J Schlager, March 17, 1992: US05096062 (56 worldwide citation)

A transport system for shipping microbiological specimen samples which maintains the life of the bacteria contained in the sample and protects the environment from escape of samples comprises:


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Navnit Hargovindas Shah, Max Zeller: Tetrahydrolipstatin containing compositions. Hoffman La Roche, George W Johnston, William H Epstein, John P Parise, December 21, 1999: US06004996 (56 worldwide citation)

Product containing tetrahydrolipstatin as the active ingredient and pharmaceutically acceptable excipients, characterized in that it is in the form of particles with a diameter of 0.25 to 2 mm; and pharmaceutical preparation s or compositions for oral administration containing the product.


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Heinz Dobeli, Bernhard Eggimann, Reiner Gentz, Erich Hochuli, Dietrich Stuber: Affinity peptides. Hoffmann La Roche, George M Gould, William H Epstein, February 8, 1994: US05284933 (55 worldwide citation)

Fusion proteins and a process for their purification by means of metal chelate affinity chromatography on NTA resins are provided by this invention.


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Jurg Buhler, Andreas Greter: Apparatus for chemical and biochemical analysis of samples. Hoffmann La Roche, George W Johnston, William H Epstein, John P Parise, June 9, 1998: US05762872 (54 worldwide citation)

The analytical device comprises a conveyor for conveying cuvettes to one or more stations for processing samples for analysis in the cuvettes. The processing stations comprise means for removing individual cuvettes from the conveyor, transferring the cuvettes to a processing position and returning t ...


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Gottfried Alber, Jacqueline Anne Carr, Frank Albert Mattner, Michael John Mulqueen, Kathrin Palmer, Jane Andre Louise Rogerson: Use of IL-12 and IFN.alpha. for the treatment of infectious diseases. Hoffmann La Roche, George W Johnson, William H Epstein, Briana C Buchholz, July 27, 1999: US05928636 (54 worldwide citation)

The present invention provides a combination of IL-12 and IFN.alpha. together with a pharmaceutically acceptable carrier useful for treatment and prophylaxis of infectious diseases, preferably chronic infectious diseases and more preferably viral infections, e.g. HSV, HIV, Hepatitis B, Hepatitis C, ...


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Edmund F Byrne, Glen L Tolman: Bifunctional chelating agents. Medi Physics, Jon S Saxe, George M Gould, William H Epstein, March 11, 1986: US04575556 (54 worldwide citation)

Novel homocysteine thiolactone bifunctional chelating agents useful for chelating radionuclides to produce a radiodiagnostic agent for use in in vivo imaging and a method for producing this chelating agent.


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John Hakimi, Patricia Kilian, Perry Rosen: Polymer for making poly(ethylene glycol)-protein conjugates. Hoffmann La Roche, George M Gould, William H Epstein, Catherine R Smith, July 23, 1996: US05539063 (50 worldwide citation)

The present invention is a polymer which may be used to produce a physiologically active, substantially non-immunogenic water soluble polyethylene glycol protein conjugate having the same utility as the protein which forms the conjugate, without having the same properties of producing an immunogenic ...


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Edmund F Byrne, Glen L Tolman: Homocysteine and homocysteinamide derivatives. Medi Physics, Jon S Saxe, George M Gould, William H Epstein, February 18, 1986: US04571430 (50 worldwide citation)

Novel homocysteine thiolactone bifunctional chelating agents useful for chelating radionuclides to produce a radiodiagnostic agent for use in vivo imaging and a method for producing this chelating agent.