1
Fu Wen Shen, Harry A McKellop, Ronald Salovey: Crosslinking of polyethylene for low wear using radiation and thermal treatments. The Orthopaedic Hospital and University of Southern California, Wean Khing Wong, May 8, 2001: US06228900 (199 worldwide citation)

The present invention discloses methods for enhancing the wear-resistance of polymers, the resulting polymers, and in vivo implants made from such polymers. One aspect of this invention presents a method whereby a polymer is irradiated, preferably with gamma radiation, then thermally treated, such a ...


2
Benton A Durley III, James D Defreese, Carl W Merkh: Test card for performing assays. Abbott Laboratories, Wean Khing Wong, Priscilla E Porembski, December 24, 1991: US05075077 (164 worldwide citation)

A semi-automated biological sample analyzer and subsystems are provided to simultaneously perform a plurality of enzyme immuno assays for human IgE class antibodies specific to a panel of preselected allergens in each of a plurality of biological samples. A carousel is provided to position and hold ...


3
Ronald Salovey, Harry A McKellop, Fu Wen Shen: Chemically crosslinked ultrahigh molecular weight polyethylene for artificial human joints. The Orthopaedic Hospital, University of Southern California, Wean Khing Wong, August 28, 2001: US06281264 (160 worldwide citation)

The present invention discloses a method for enhancing the wear-resistance of polymers by crosslinking them, especially before irradiation sterilization. In particular, this invention presents the use of chemically crosslinked ultrahigh molecular weight polyethylene in in vivo implants.


4
Harry Alden McKellop, Fu Wen Shen: Wear resistant surface-gradient crosslinked polyethylene. The Orthopaedic Hospital, University of Southern California, Wean Khing Wong, December 26, 2000: US06165220 (94 worldwide citation)

A method for improving the wear resistance of an implant by crosslinking its bearing surface layer, while leaving its non-bearing interior uncrosslinked. Such crosslinking may be achieved by electron-beam irradiation or by chemical crosslinking of the implant. The resulting implant may be further tr ...


5
Fu Wen Shen, Harry A McKellop, Ronald Salovey: Crosslinking of polyethylene for low wear using radiation and thermal treatments. Orthopaedic Hospital, University of Southern California, Wean Khing Wong, October 5, 2004: US06800670 (86 worldwide citation)

The present invention discloses methods for enhancing the wear-resistance of polymers, the resulting polymers, and in vivo implants made from such polymers. One aspect of this invention presents a method whereby a polymer is irradiated, preferably with gamma radiation, then thermally treated, such a ...


6
Harry A McKellop, Fu Wen Shen: Wear resistant surface-gradient crosslinked polyethylene. Orthopaedic Hospital, University of Southern California, Wean Khing Wong, December 17, 2002: US06494917 (80 worldwide citation)

A method for improving the wear resistance of an implant, made of polyethylene, by crosslinking its bearing surface layer, while leaving its non-bearing interior uncrosslinked. Such crosslinking may be achieved by electron-beam irradiation or by chemical crosslinking of the implant or the polyethyle ...


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8
Frank Emile Bailly: Device for securing spinal rods. Wean Khing Wong, Liu & Liu, August 3, 2010: US07766946 (46 worldwide citation)

The present invention is directed to a device for securing a spinal rod to a fixation device such as a pedicle screw or a lamina hook. The device disclosed herein includes a head portion configured to receive a spinal rod, a locking cap configured to engage the head portion and the spinal rod upon r ...


9
Brian L Maiorella: In vitro management of ammonias effect on glycosylation of cell products through pH control. Cetus Corporation, Gregory J Giotta, Wean Khing Wong, March 17, 1992: US05096816 (42 worldwide citation)

This invention relates generally to the field of cell culture. The invention presents pH based methods for controlling the glycosylation patterns of cell products, particularly proteins produced by cells in vitro, preferably via a multi-level pH control strategy. Preferably, this invention is applie ...


10
Duane Inlow, Brian Maiorella: Serum free media for the growth on insect cells and expression of products thereby. Cetus Corporation, Leona L Lauder, Wean Khing Wong, June 18, 1991: US05024947 (41 worldwide citation)

Serum-free media which support the growth of insect cells and the production thereby of recombinant proteins and viral products are herein disclosed. The serum free media can support insect cell growth at large scale under agitated and/or sparged, preferably well-aerated conditions.