1
Mark Munson, David A Mareska, Youngboo Kim, Robert D Gronenberg, James P Rizzi, Martha Rodriguez, Ganghyeok Kim, Guy Vigers, Chang Rao, Devan Balachari, Darren Harvey: P38 inhibitors and methods of use thereof. Array BioPharma, John R Moore Esq, Viksnins Harris & Padys PLLP, September 21, 2010: US07799782 (181 worldwide citation)

This invention relates to inhibitors of p38 and methods of utilizing the inhibitors and pharmaceutical compositions thereof in the treatment and prevention of various disorders mediated by p38.


2
Aly A Farag, David Tasman, Sameh M Yamany: System and method for 3-D digital reconstruction of an oral cavity from a sequence of 2-D images. University of Louisville Research Foundation, Viksnins Harris & Padys PLLP, August 1, 2006: US07084868 (72 worldwide citation)

Systems and methods are provided through which a model-based vision system for dentistry which assists in diagnosis, treatment planning and surgical simulation. The present invention includes an integrated computer vision system that constructs a three-dimensional (3-D) model of the patient's dental ...


3
Paul B McCray, Beverly L Davidson, Anthony J Fischer, Hong P Jia, Maureen D Donovan, Patrick L Sinn, Mark Aaron Behlke: RNA interference in respiratory epitheial cells. University of Iowa Research Foundation, Viksnins Harris & Padys PLLP, November 20, 2007: US07297786 (70 worldwide citation)

The present invention is directed to small interfering RNA molecules targeted against a gene of interest in respiratory epithelial cells, and methods of using these RNA molecules.


4
Jerome Legerton, Randall Sprague: Method and apparatus for constructing a contact lens with optics. Innovega, Viksnins Harris & Padys PLLP, March 27, 2012: US08142016 (58 worldwide citation)

Various embodiments of the present invention provide systems, methods, and processes for constructing a contact lens. In one embodiment, a contact lens assembly is provided, comprising: a curved polymer polarizer with an aperture; a lenslet disposed inside the aperture, wherein the lenslet enables i ...


5
James Heyes, Lorne Palmer, Magdalena Maslowski, Ian MacLachlan: Cationic lipids and methods for the delivery of therapeutic agents. Protiva Biotherapeutics, Viksnins Harris & Padys PLLP, October 29, 2013: US08569256 (52 worldwide citation)

The present invention provides compositions and methods for the delivery of therapeutic agents to cells. In particular, these include novel cationic lipids and nucleic acid-lipid particles that provide efficient encapsulation of nucleic acids and efficient delivery of the encapsulated nucleic acid t ...


6
Hongyan Guo, Darryl Kato, Thorsten A Kirschberg, Hongtao Liu, John O Link, Michael L Mitchell, Jay P Parrish, Jianyu Sun, James Taylor, Elizabeth M Bacon, Eda Canales, Aesop Cho, Choung U Kim, Jeromy J Cottell, Manoj C Desai, Randall L Halcomb, Scott E Lazerwith, Richard L Mackman, Hyung Jung Pyun, Joseph H Saugier, James D Trenkle, Winston C Tse, William J Watkins, Lianhong Xu: Antiviral compounds. Gilead Sciences, Viksnins Harris & Padys PLLP, January 3, 2012: US08088368 (39 worldwide citation)

The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.


7
Muthiah Manoharan, Kallanthottathil G Rajeev, Akin Akinc, Narayanannair K Jayaprakash, Muthusamy Jayaraman, Martin Maier: Lipid containing formulations. Tekmira Pharmaceuticals Corporation, Viksnins Harris & Padys PLLP, February 4, 2014: US08642076 (36 worldwide citation)

Compositions and methods useful in administering nucleic acid based therapies, for example association complexes such as liposomes and lipoplexes are described.


8
Ian S Mitchell, James F Blake, Rui Xu, Nicholas C Kallan, Dengming Xiao, Keith Lee Spencer, Josef R Bencsik, Eli M Wallace, Stephen T Schlachter, Anna L Banka, Jun Liang, Brian Safina, Birong Zhang, Christine Chabot, Steven Do: Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors. Array BioPharma, Covenentech, Viksnins Harris & Padys PLLP, November 22, 2011: US08063050 (25 worldwide citation)

The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula I: Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatmen ...


9
Constantine G Boojamra, Carina Cannizzaro, James M Chen, Xiaowu Chen, Aesop Cho, Lee S Chong, Maria Fardis, Alan X Huang, Choung U Kim, Thorsten Kirschberg, Steven Krawczyk, Christopher P Lee, Kuei Ying Lin, Richard L Mackman, David Y Markevitch, Peter H Nelson, David A Oare, Vidya K Prasad, Hyung Jung Pyun, Adrian S Ray, Sundaramoorthi Swaminathan, William J Watkins, Jennifer R Zhang, Lijun Zhang: Anti-cancer phosphonate analogs. Gilead Sciences, Viksnins Harris & Padys PLLP, November 18, 2008: US07452901 (24 worldwide citation)

The invention is related to phosphorus substituted anti-cancer compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.


10
Shohel Koide: Artificial antibody polypeptides. Research Corporation Technologies, Viksnins Harris & Padys PLLP, July 18, 2006: US07078490 (24 worldwide citation)

A fibronectin type III (Fn3) polypeptide monobody, a nucleic acid molecule encoding a monobody, and a variegated nucleic acid library encoding a monobody, are provided by the invention. Also provided are methods of preparing an Fn3 polypeptide monobody, and kits to perform such methods. Further prov ...



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