Mark Munson, David A Mareska, Youngboo Kim, Robert D Gronenberg, James P Rizzi, Martha Rodriguez, Ganghyeok Kim, Guy Vigers, Chang Rao, Devan Balachari, Darren Harvey: P38 inhibitors and methods of use thereof. Array BioPharma, John R Moore Esq, Viksnins Harris & Padys PLLP, September 21, 2010: US07799782 (189 worldwide citation)

This invention relates to inhibitors of p38 and methods of utilizing the inhibitors and pharmaceutical compositions thereof in the treatment and prevention of various disorders mediated by p38.

Paul B McCray, Beverly L Davidson, Anthony J Fischer, Hong P Jia, Maureen D Donovan, Patrick L Sinn, Mark Aaron Behlke: RNA interference in respiratory epitheial cells. University of Iowa Research Foundation, Viksnins Harris & Padys PLLP, November 20, 2007: US07297786 (79 worldwide citation)

The present invention is directed to small interfering RNA molecules targeted against a gene of interest in respiratory epithelial cells, and methods of using these RNA molecules.

Aly A Farag, David Tasman, Sameh M Yamany: System and method for 3-D digital reconstruction of an oral cavity from a sequence of 2-D images. University of Louisville Research Foundation, Viksnins Harris & Padys PLLP, August 1, 2006: US07084868 (77 worldwide citation)

Systems and methods are provided through which a model-based vision system for dentistry which assists in diagnosis, treatment planning and surgical simulation. The present invention includes an integrated computer vision system that constructs a three-dimensional (3-D) model of the patient's dental ...

Jerome Legerton, Randall Sprague: Method and apparatus for constructing a contact lens with optics. Innovega, Viksnins Harris & Padys PLLP, March 27, 2012: US08142016 (66 worldwide citation)

Various embodiments of the present invention provide systems, methods, and processes for constructing a contact lens. In one embodiment, a contact lens assembly is provided, comprising: a curved polymer polarizer with an aperture; a lenslet disposed inside the aperture, wherein the lenslet enables i ...

James Heyes, Lorne Palmer, Magdalena Maslowski, Ian MacLachlan: Cationic lipids and methods for the delivery of therapeutic agents. Protiva Biotherapeutics, Viksnins Harris & Padys PLLP, October 29, 2013: US08569256 (55 worldwide citation)

The present invention provides compositions and methods for the delivery of therapeutic agents to cells. In particular, these include novel cationic lipids and nucleic acid-lipid particles that provide efficient encapsulation of nucleic acids and efficient delivery of the encapsulated nucleic acid t ...

Hongyan Guo, Darryl Kato, Thorsten A Kirschberg, Hongtao Liu, John O Link, Michael L Mitchell, Jay P Parrish, Jianyu Sun, James Taylor, Elizabeth M Bacon, Eda Canales, Aesop Cho, Choung U Kim, Jeromy J Cottell, Manoj C Desai, Randall L Halcomb, Scott E Lazerwith, Richard L Mackman, Hyung Jung Pyun, Joseph H Saugier, James D Trenkle, Winston C Tse, William J Watkins, Lianhong Xu: Antiviral compounds. Gilead Sciences, Viksnins Harris & Padys PLLP, January 3, 2012: US08088368 (39 worldwide citation)

The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

Muthiah Manoharan, Kallanthottathil G Rajeev, Akin Akinc, Narayanannair K Jayaprakash, Muthusamy Jayaraman, Martin Maier: Lipid containing formulations. Tekmira Pharmaceuticals Corporation, Viksnins Harris & Padys PLLP, February 4, 2014: US08642076 (36 worldwide citation)

Compositions and methods useful in administering nucleic acid based therapies, for example association complexes such as liposomes and lipoplexes are described.

Suseela Kanamathareddy, Stephen Goodrich, Yun Choe: Solution polymerization processes to prepare a polymer that degrades to release a physiologically active agent. Rutgers The State University of New Jersey, Viksnins Harris & Padys PLLP, February 16, 2010: US07662864 (27 worldwide citation)

Anhydride polymers that release active or activatable agent(s) have pre-selected properties such as molecular weight, flexibility, hardness, adhesiveness, and other valuable properties. The polymers are suitable for use in compositions, formulations, coatings, devices, and the like that benefit from ...

Ian S Mitchell, James F Blake, Rui Xu, Nicholas C Kallan, Dengming Xiao, Keith Lee Spencer, Josef R Bencsik, Eli M Wallace, Stephen T Schlachter, Anna L Banka, Jun Liang, Brian Safina, Birong Zhang, Christine Chabot, Steven Do: Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors. Array BioPharma, Covenentech, Viksnins Harris & Padys PLLP, November 22, 2011: US08063050 (26 worldwide citation)

The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula I: Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatmen ...

Shohei Koide: Binding polypeptides. Research Corporation Technologies, Viksnins Harris & Padys PLLP, October 10, 2006: US07119171 (26 worldwide citation)

The present invention provides modified fibronectin type III (Fn3) molecules, nucleic acid molecules encoding the modified Fn3 molecules, and related vectors and host cells.