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Donna L Romero, Matthew David Wessel, Shaughnessy Robinson, Jeremy Robert Greenwood, Karl Shawn Watts, Leah Lynn Frye, Geraldine C Harriman, Alan Franklin Corin, Craig E Masse, Mee Shelley: IRAK inhibitors and uses thereof. Nimbus Iris, Choate Hall & Stewart, Andrea C Robidoux, Thomas H McLean, April 22, 2014: US08703941 (8 worldwide citation)

The present invention provides thienopyrimidine and thienopyridine compounds, compositions thereof, and methods of using the same for the treatment of diseases mediated by IRAK enzymes. Such diseases include inflammatory and proliferative diseases.


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Donna L Romero, Shaughnessy Robinson, Matthew David Wessel, Jeremy Robert Greenwood: IRAK inhibitors and uses thereof. Nimbus Iris, Choate Hall & Stewart, Andrea L C Reid, Thomas H McLean, July 21, 2015: US09085586 (2 worldwide citation)

The present invention provides arylo-fused thienopyrimidine compounds, compositions thereof, and methods of using the same.


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Geraldine C Harriman, Craig E Masse, James Harwood, Sathesh Bhat, Jeremy Robert Greenwood: ACC inhibitors and uses thereof. Nimbus Apollo, Choate Hall & Stewart, Andrea L C Reid, Thomas H McLean, March 3, 2015: US08969557 (1 worldwide citation)

The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.


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Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Dasari Muralidhara Reddy, Samala Malla Reddy, Bandi Vamsi Krishna: Polymorphs of pitavastatin calcium. Hetero Research Foundation, Choate Hall & Stewart, Charles E Lyon, Thomas H McLean, December 16, 2014: US08912333

The present invention provides a solid of pitavastatin tert-butyl ester and process for its preparation. The present invention also provides a novel crystalline form of pitavastatin calcium, process for its preparation and pharmaceutical compositions comprising it.


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Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Dasari Muralidhara Reddy, Rapolu Raji Reddy, Jambula Mukunda Reddy, Bandi Vamsi Krishna: Process for cinacalcet hydrochloride. Hetero Research Foundation, Choate Hall & Stewart, Charles E Lyon, Thomas H McLean, December 30, 2014: US08921606

3-[3-(Trifluoromethyl)phenyl]propionaldehyde is a key intermediate for the preparation of cinacalcet hydrochloride. The present invention provides a novel process for the preparation of 3-[3-(trifluoromethyl)phenyl]propionaldehyde. The present invention also provides an improved process for preparat ...