1
Robert McCaffrey, Katarina Tkacik, Brian Holman, James Flaherty, Josef Brown, Peter Edelman: Sensors for measuring analyte concentrations and methods of making same. Chiron Diagnostics Corporation, Arthur S Morgenstern, Stanley Sacks, Robert P Blackburn, January 13, 1998: US05707502 (397 worldwide citation)

A sensor for measuring a concentration of an analyte in a solution. The sensor comprises a substrate layer, an electrode layer and an immobilized enzyme layer. The sensor further includes an enzyme/polymer layer and/or a hydrophobic layer. The enzyme/polymer layer includes an enzyme disposed within ...


2
Klaus Brendel, Raymond C Duhamel: Body implants of extracellular matrix and means and methods of making and using such implants. University Patents, Barbara A Shimei, Stanley Sacks, January 31, 1989: US04801299 (315 worldwide citation)

A sterile body implant is derived from a body structure having as its major protein component collagens in the form of extracellular matrix. The body structure is treated to remove cellular membranes, nucleic acids, lipids and cytoplasmic components. Such structures are implanted internally in the b ...


3
Thomas C Maley, Mark W Boden, Paul A D Orazio, Peter G Edelman: Glucose and lactate sensors. Chiron Diagnostics Corporation, Arthur S Morgenstern, Stanley Sacks, Robert P Blackburn, June 23, 1998: US05770028 (214 worldwide citation)

A solid state, multi-use electrochemical sensor having an electrically nonconductive substrate, a working electrode, and a semi-permeable membrane covering the working electrode. The working electrode includes an electrically conductive material adhered to a portion of the substrate. A first portion ...


4
Thomas C Maley, Paul A D Orazio, Bonnie C Dalzell, Peter G Edelman, James E Flaherty, Richard W Mason, Robert R McCaffrey: Electrochemical sensors membrane. Chiron Diagnostics Corporatiion, Arthur S Morgenstern, Stanley Sacks, Robert P Blackburn, January 27, 1998: US05711868 (173 worldwide citation)

A solid state, multi-use electrochemical sensor having an electrically nonconductive substrate, a working electrode, and a semi-permeable membrane covering the working electrode. The working electrode includes an electrically conductive material adhered to a portion of the substrate. A first portion ...


5
Robert McCaffrey, Bonnie Dalzell, Katarina Tkacik, Susan Holbert, Mark Boden, James Flaherty, Michael Flanagan, Josef Brown, Kimiya Takeshita, Peter Edelman: Multilayer enzyme electrode membranes and methods of making same. Chiron Diagnostics Corporation, Arthur S Morgenstern, Stanley Sacks, Robert P Blackburn, December 9, 1997: US05696314 (170 worldwide citation)

An electrochemical sensor is designed for use in detecting a concentration of an analyte in a sample solution. The sensor to have a longer useful lifetime, improved stability and improved response time for single or multiple use applications. In one aspect, some of these goals are achieved by provid ...


6
Allison L Abel, Paul A D Orazio, Bonnie C Dalzell, Robert R McCaffrey, Laura S Uretsky: Reagents with enhanced performance in clinical diagnostic systems. Chiron Diagnostics Corporation, Arthur S Morgenstern, Stanley Sacks, Robert P Blackburn, September 16, 1997: US05667983 (137 worldwide citation)

It has been found that imidazole and related buffers enhance the activity of certain preservatives, for example either (1) a mixture of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one or (2) 5-bromo-5-nitro-1,3-dioxane, that are used in clinical diagnostic reagents. It has a ...


7
Thomas C Maley, Paul A D Orazio, Peter G Edelman, John A Zalenski: Electrochemical sensors paste. Chiron Diagnostics Corporation, Judith A Roesler, Stanley Sacks, Robert Blackburn, April 1, 1997: US05616222 (132 worldwide citation)

A solid state, multi-use electrochemical sensor having an electrically nonconductive substrate, a working electrode, and a semi-permeable membrane covering the working electrode. The working electrode includes an electrically conductive material adhered to a portion of the substrate. A first portion ...


8
Ann B Salamone, Joseph C Salamone, Alfred P Olson: Conformable bandage and coating material. Rochal, Rochal, Stanley Sacks, Stanley Sacks, April 14, 1992: US05103812 (25 worldwide citation)

Combinations of alkyl siloxy siloxane-containing polymers admixed with liquid polydimethylsiloxanes are excellent non-stinging, non-irritating liquid coating material for forming films which act as conformable bandages adhering to and protecting nails, skin and mucous membrane wounds from abrasion, ...


9
Andy D C Chan: Material for establishing solid state contact for ion selective electrodes. Chiron Diagnostics Corporation, Arthur S Morgenstern, Stanley Sacks, Robert P Blackburn, September 8, 1998: US05804049 (24 worldwide citation)

A polymeric material which to form a stable, reproducible interface between the ionic and electronic domains of an ion selective sensor, or an ion selective field effect transistor, or the like is provided. When employed in an ion selective sensor, the polymeric material is advantageously provided o ...


10
Andy D C Chan: Material for establishing solid state contact for ion selective electrodes. Chiron Diagnostics Corporation, Arthur S Morgenstern, Stanley Sacks, June 15, 1999: US05911862 (10 worldwide citation)

A polymeric material which to form a stable, reproducible interface between the ionic and electronic domains of an ion selective sensor, or an ion selective field effect transistor, or the like is provided. When employed in an ion selective sensor, the polymeric material is advantageously provided o ...