1
Endre A Balazs, Adolf Leshchiner: Cross-linked gels of hyaluronic acid and products containing such gels. Biomatrix, Sheldon Palmer, April 15, 1986: US04582865 (244 worldwide citation)

Disclosed are cross-linked gels of hyaluronic acid, alone or mixed with other hydrophilic polymers and containing various substances or covalently bonded low molecular weight substances and processes for preparing them. These products are useful in numerous applications including cosmetic formulatio ...


2
Endre A Balazs, Adolf Leshchiner, Nancy E Larsen: Drug delivery systems based on hyaluronans derivatives thereof and their salts and methods of producing same. Biomatrix, Sheldon Palmer, July 7, 1992: US05128326 (240 worldwide citation)

Disclosed are drug delivery systems based on a polymeric component which is soluble or insoluble (cross-linked) hyaluronan or hyaluronan copolymerized with another hydrophilic polymer or hylan and one or more substances having biological or pharmacological activity and methods of preparing same.


3
Edward Leshchiner, Endre A Balazs, Nancy E Larsen, Adelva Leshchiner: Biocompatible viscoelastic gel slurries, their preparation and use. Biomatrix, Sheldon Palmer, March 21, 1995: US05399351 (136 worldwide citation)

Disclosed are biocompatible viscoelastic gel slurries formed from a polymeric gel, preferably a hyaluronan or a derivative thereof such as hylan swollen in an aqueous medium and a fluid phase which is an aqueous solution of a polymer which may also but not necessarily be a hyaluronan or derivative t ...


4
Endre A Balazs, Adolf Leshchiner: Cross-linked gels of hyaluronic acid and products containing such gels. Biomatrix, Sheldon Palmer, January 13, 1987: US04636524 (135 worldwide citation)

Disclosed are cross-linked gels of hyaluronic acid, alone or mixed with other hydrophilic polymers and containing various substances or covalently bonded low molecular weight substances and processes for preparing them. These products are useful in numerous applications including cosmetic formulatio ...


5
Adolf Leshchiner, Nancy E Larsen, Endre A Balazs, Sadek K Hilal: Compositions for therapeutic percutaneous embolization and the use thereof. Biomatrix, Sheldon Palmer, January 3, 1989: US04795741 (131 worldwide citation)

Percutaneous emboli are formed for therapeutic and/or corrective reasons by using a composition which includes crosslinked gells of hyaluronic acid (HA), hylan (HY) or mixed crosslinked gels of HA or HY with other materials, thrombin and cationic substances containing quaternary ammonium groups. Oth ...


6
Edward Leshchiner, Endre A Balazs, Nancy E Larsen, Adelya Leshchiner: Biocompatible viscoelastic gel slurries, their preparation and use. Biomatrix, Sheldon Palmer, September 1, 1992: US05143724 (125 worldwide citation)

Disclosed are biocompatible viscoelastic gel slurries formed from a polymeric gel, preferably a hyaluronan or a derivative thereof such as hylan swollen in an aqueous medium and a fluid phase which is an aqueous solution of a polymer which may also but not necessarily be a hyaluronan or derivative t ...


7
Endre A Balazs, Adolf Leshchiner, Adelya Leshchiner, Philip Band: Chemically modified hyaluronic acid preparation and method of recovery thereof from animal tissues. Biomatrix, Sheldon Palmer, December 15, 1987: US04713448 (117 worldwide citation)

Disclosed is hylan, a chemically modified hyaluronic acid preparation characterized by the presence of small amounts (0.005-0.05% by weight) of aldehyde cross-linking groups covalently bonded to the hyaluronic acid molecular chains. Also disclosed is a method of obtaining hylan comprising treating h ...


8
Endre A Balazs, Adolf Leshchiner: Hyaluronate modified polymeric articles. Biomatrix, Sheldon Palmer, February 19, 1985: US04500676 (101 worldwide citation)

Polymeric materials (and articles made therefrom) including polyurethanes, polyesters, polyolefins, polyamides, polysiloxanes, vinylic and acrylic polymers are rendered biocompatible by including with the polymeric material hyaluronic acid or a salt thereof. The hyaluronic acid may be coated onto th ...


9
Endre A Balazs, Adolf Leshchiner: Cross-linked gels of hyaluronic acid and products containing such gels. Biomatrix, Sheldon Palmer, August 12, 1986: US04605691 (99 worldwide citation)

Disclosed are cross-linked gels of hyaluronic acid, alone or mixed with other hydrophilic polymers and containing various substances or covalently bonded low molecular weight substances and processes for preparing them. These products are useful in numerous applications including cosmetic formulatio ...


10
Edward Leshchiner, Endre A Balazs, Nancy E Larsen, Adelya Leshchiner: Biocompatible viscoelastic gel slurries, their preparation and use. Biomatrix, Sheldon Palmer, September 21, 1993: US05246698 (93 worldwide citation)

Disclosed are biocompatible viscoelastic gel slurries formed from a polymeric gel, preferably a hyaluronan or a derivative thereof such as hylan swollen in an aqueous medium and a fluid phase which is an aqueous solution of a polymer which may also but not necessarily be a hyaluronan or derivative t ...



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