1
Lionel M Nelson, Ronald G Lax, Eric N Doelling: Systems and methods for moving and/or restraining the tongue in the oral cavity. Apneon, Ryan Krumholz & Manion S C, October 18, 2005: US06955172 (124 worldwide citation)

Systems and related methods treat snoring and other sleep related disorders by stabilizing the position of a tongue in an oral cavity. The systems and methods employ an operative element sized and configured to be fitted to less mobile tissue in the oral cavity. The operative element is further cons ...


2
Stuart D Edwards, John Gaiser, David S Utley, Scott H West, Jay Qin: Systems and methods for forming composite lesions to treat dysfunction in sphincters and adjoining tissue regions. Curon Medical, Ryan Krumholz & Manion S C, March 30, 2004: US06712074 (114 worldwide citation)

Systems and methods manipulate a support structure to form a composite lesion in a tissue region at or near a sphincter. The support structure carries an array of electrodes attachable to a source of energy capable of heating tissue when transmitted by the electrodes. The systems and methods advance ...


3
Joseph J Mrva, Robert B Strother, Geoffrey B Thrope, Julie Grill, Maria Bennett: Method for affecting urinary function with electrode implantation in adipose tissue. NDI Medical, Ryan Krumholz & Manion S C, March 11, 2008: US07343202 (53 worldwide citation)

Systems and methods provide a stimulation electrode assembly comprising an elongated lead sized and configured to be implanted within an adipose tissue region. The lead includes an electrically conductive portion to apply electrical stimulation to nerve or muscle in the adipose tissue region and at ...


4
Peter J Jenquin, John A McCabe, Thomas R Coose: Staggered cutting knife. Curt G Joa, Ryan Krumholz & Manion S C, January 4, 2011: US07861756 (37 worldwide citation)

A method and apparatus for producing disposable undergarments having areas of defined elastic material is disclosed. The method provides for staggered cutting knives for severing the elastic material, which results in less necessary material used in the construction of the undergarments.


5
Zi Ping Fang, Maria E Walker: Treatment of shoulder dysfunction using a percutaneous intramuscular stimulation system. SPR Therapeutics, Ryan Krumholz & Manion S C, August 21, 2012: US08249713 (35 worldwide citation)

A method of treating shoulder dysfunction involves the use of a percutaneous, intramuscular stimulation system. A plurality of intramuscular stimulation electrodes are implanted directly into select shoulder muscles of a patient who has suffered a disruption of the central nervous system such as a s ...


6
Timothy R Machold, Robert T Chang, David A Rahdert, David Scott, David R Tholfsen: Devices, systems, and methods for reshaping a heart valve annulus, including the use of magnetic tools. MVRx, Ryan Krumholz & Manion S C, April 8, 2014: US08690858 (20 worldwide citation)

Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascula ...


7
Olexander Hnojewyj, Bruce Addis, Daniel Browne, David Cheung: Systems, methods, and compositions for achieving closure of suture sites. NeoMend, Ryan Krumholz & Manion S C, April 1, 2008: US07351249 (13 worldwide citation)

Systems and methods employ functional instruments to close incisions and wounds using a suture knot in combination with a biocompatible material composition. The systems and methods are well suited for use, for example, at a vascular puncture site following a vascular access procedure.


8
Robert E Low: Heat transfer compositions. Mexichem Amanco Holding de C V, Ryan Krumholz & Manion S C, December 18, 2012: US08333901 (10 worldwide citation)

The invention provides a heat transfer composition comprising R-1234ze(E), R-32 and 1,1,1,2-tetrafluoroethane (R-134a).


9
Robert B Strother, Geoffrey B Thrope, Joseph J Mrva, Steven M Galecki, Danny R Pack, Christopher A Thierfelder, James Coburn: Systems and methods for intra-operative stimulation. Checkpoint Surgical, Ryan Krumholz & Manion S C, May 8, 2012: US08172768 (4 worldwide citation)

Improved assemblies, systems, and methods provide safeguarding against tissue injury during surgical procedures and/or identify nerve damage occurring prior to surgery and/or verify range of motion or attributes of muscle contraction during reconstructive surgery. A stimulation control device may in ...


10
Harry Appleman: Sectional bicycle. A Enterprises, Ryan Krumholz & Manion S C, October 15, 2013: US08556284 (3 worldwide citation)

A modular bicycle comprising a first section having a front frame section and a first tire, a second section being couplable to the first section and comprising a central frame, and a third section being couplable to the second section and the first section, with the third section comprising a rear ...