1
Bret Berner, Timothy C Dunn, Kathleen C Farinas, Michael D Garrison, Ronald T Kurnik, Matthew J Lesho, Russell O Potts, Janet A Tamada, Michael J Tierney: Signal processing for measurement of physiological analysis. Cygnus, Barbara G McClung, Robins & Associates, May 15, 2001: US06233471 (851 worldwide citation)

A method is provided for continually or continuously measuring the concentration of target chemical analytes present in a biological system, and processing analyte-specific signals to obtain a measurement value that is closely correlated with the concentration of the target chemical analyte in the b ...


2
Ronald T Kurnik: Method and device for predicting physiological values. Cygnus, Barbara G McClung, Robins & Associates, August 7, 2001: US06272364 (564 worldwide citation)

A method and device are provided for measuring the concentration of target chemical analytes present in a biological system, and then predicting a future or past concentration of an analyte using a series of such measurements. One important application of the invention involves predicting future or ...


3
Bret Berner, Chia Ming Chiang, Michael D Garrison, Janan Jona, Russell O Potts, Janet A Tamada, Michael J Tierney: Monitoring of physiological analytes. Cygnus, Barbara G Robins & Associates McClung, November 7, 2000: US06144869 (516 worldwide citation)

Methods and devices are provided for measuring the concentration of target chemical analytes present in a biological system. Device configuration and/or measurement techniques are employed in order to reduce the effect of interfering species on sensor sensitivity. One important application of the in ...


4
Ronald T Kurnik, Janet Tamada, Michael Tierney, Russell Owen Potts: Methods for monitoring a physiological analyte. Cygnus, Barbara G McClung, Robins & Associates, October 9, 2001: US06299578 (457 worldwide citation)

A method for continual monitoring of a physiologic analyte in a subject includes steps of contacting the subject with a collection reservoir such that the analyte can move from the subject into the collection reservoir, the contents of the collection reservoir being in operative communication with a ...


5
Ronald T Kurnik, Jonathan James Oliver, Russell O Potts, Steven Richard Waterhouse, Timothy C Dunn, Yalia Jayalakshmi, Matthew J Lesho, Janet A Tamada, Charles W Wei: Method and device for predicting physiological values. Cygnus, Barbara G McClung, Robins & Associates, January 30, 2001: US06180416 (421 worldwide citation)

The invention relates generally to methods, systems, and devices for measuring the concentration of target analytes present in a biological system using a series of measurements obtained from a monitoring system and a Mixtures of Experts (MOE) algorithm. In one embodiment, the present invention desc ...


6
Ronald T Kurnik, Janet Tamada, Michael Tierney: Chemical signal-impermeable mask. Cygnus, Barbara G Robins & Associates McClung, October 31, 2000: US06141573 (162 worldwide citation)

A chemical signal-impermeable mask is positioned in the electrolyte flow such that the mask is between a source of chemical signal and a working electrode which senses the chemical signal transported from the source (e.g., by diffusion). The configuration of the mask is such that the mask prevents s ...


7
Ronald T Kurnik, Janet Tamada, Michael Tierney: Chemical signal-impermeable mask. Cygnus, Barbara G McClung, Robins & Associates, March 13, 2001: US06201979 (146 worldwide citation)

A chemical signal-impermeable mask is positioned in the electrolyte flow such that the mask is between a source of chemical signal and a working electrode which senses the chemical signal transported from the source (e.g., by diffusion). The configuration of the mask is such that the mask prevents s ...


8
Ronald T Kurnik, Janet Tamada, Michael J Tierney: Electrode with improved signal to noise ratio. Cygnus, Barbara G Robins & Associates McClung, October 31, 2000: US06139718 (146 worldwide citation)

An electrode assembly for sensing an electrochemical signal diffused from a source to a working electrode which is comprised of a plurality of substantially separated working electrode surfaces is disclosed. The electrode of the invention is comprised of 1) a working electrode made up of a plurality ...


9
Gregory M Podsakoff, Paul D Kessler, Barry J Byrne, Gary J Kurtzman: Methods for delivering DNA to muscle cells using recombinant adeno-associated virus vectors. Avigen, Johns Hopkins University, Robins & Associates, January 12, 1999: US05858351 (62 worldwide citation)

The use of recombinant adeno-associated virus (AAV) virions for delivery of DNA molecules to muscle cells and tissue is disclosed. The invention allows for the direct, in vivo injection of recombinant AAV virions into muscle tissue, e.g., by intramuscular injection, as well as for the in vitro trans ...


10
Brian J Bellhouse, David F Sarphie, John C Greenford: Needleless syringe using supersonic gas flow for particle delivery. Powderject Research, Thomas P McCracken, Robins & Associates, May 4, 1999: US05899880 (60 worldwide citation)

A needleless syringe having a membrane which is ruptured by gas pressure to generate a supersonic gas flow in which particles containing a therapeutic agent are injected.