1
Bernard Hulin, Janice C Parker: Fluorinated cyclic amides as dipeptidyl peptidase IV inhibitors. Pfizer, Peter C Richardson, Gregg C Benson, Robert T Ronau, March 23, 2004: US06710040 (53 worldwide citation)

The invention relates to new therapeutically active and selective inhibitors of the enzyme dipeptidyl peptidase-IV, pharmaceutical compositions comprising the compounds and the use of such compounds for treating diseases that are associated with proteins that are subject to processing by DPP-IV, suc ...


2
Joseph S Catania, Alton D Johnson: Taste-masking composition of bitter pharmaceutical agents. Pfizer, Peter C Richardson, Gregg C Benson, Robert T Ronau, May 27, 1997: US05633006 (52 worldwide citation)

A pharmaceutical composition having reduced bitterness consisting of a bitter pharmaceutical agent, a taste-masking component and a pharmaceutically acceptable carrier. The taste-masking component is an alkaline earth oxide, an alkaline earth hydroxide or an alkaline hydroxide and does not interfere ...


3
Andrew S Bell, Nicholas K Terrett: Pyrazolopyrimidinone antianginal agents. Pfizer, Peter C Richardson, Gregg C Benson, Robert T Ronau, June 20, 1995: US05426107 (43 worldwide citation)

Compounds of the formula ##STR1## and pharmaceutically acceptable salts thereof are selective cGMP PDE inhibitors which are useful in the treatment of such diseases and adverse conditions as angina, hypertension, congestive heart failure, reduced blood vessel patency, peripheral vascular disease, st ...


4
Bernard Hulin: 3-aryl-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents. Pfizer, Peter C Richardson, Gregg C Benson, Robert T Ronau, April 26, 1994: US05306726 (42 worldwide citation)

Certain 3-(phenyl, chroman-2-yl, benzofuran-5-yl or benzoxazol-5-yl)-2-(hydroxy or mercapto)propionic acid derivatives and analogs are useful as hypoglycemic and hypocholesterolemic agents.


5
Anthony Marfat, James F Eggler, Michael J Fray, Kelvin Cooper: Azabenzimidazoles in the treatment of asthma, arthritis and related diseases. Pfizer, Peter C Richardson, Gregg C Benson, Robert T Ronau, June 21, 1994: US05322847 (40 worldwide citation)

A series of imidazo[4,5-c]pyridines which inhibit platelet activating factor (PAF) and also block leukotriene D4 receptors are useful in treating asthma, arthritis, psoriasis, gastrointestinal distress, myocardial infarction, stroke and shock.


6
Robert L Dow, Kristin M Lundy: .beta.-adrenergic agonists. Pfizer, Peter C Richardson, Gregg C Benson, Robert T Ronau, January 12, 1999: US05859044 (38 worldwide citation)

The present invention relates to certain compounds of the formula (I) the racemic-enantiomeric mixtures and optical isomers of said compounds, prodrugs thereof and the pharmaceutically acceptable salts, depicted below, which are .beta.-adrenergic receptor agonists and accordingly have utility as, in ...


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John Christopher Danilewicz, David Ellis, Ryszard Jurek Kobylecki: Antithrombotic amidinophenylalanine and amidinopyridylalanine derivatives. Pfizer, Peter C Richardson, Gregg C Benson, Robert T Ronau, May 12, 1998: US05750520 (37 worldwide citation)

This invention relates to compounds of formula (I), ##STR1## pharmaceutically acceptable salt thereof, and pharmaceutically acceptable solvates of either entity, wherein X is CH or N; Y is optionally monousaturated C.sub.3 -C.sub.5 alkylene optionally substituted with C.sub.1 -C.sub.4 alkyl or methy ...


9
Anthony Marfat, Michael William McKechney: Thiazolyl-acid amide derivatives useful as inhibitors of PDE4 isozymes. Pfizer, Peter C Richardson, Gregg C Benson, Robert T Ronau, May 6, 2003: US06559168 (33 worldwide citation)

This application is directed to compounds useful as inhibitors of PDE4 in the treatment of diseases regulated by the activation and degranulation of eosinophils, especially asthma, chronic bronchitis, and chronic obstructuive pulmonary disease, of the formula:


10
Andrew S Bell, Nicholas K Terrett: Pyrazolopyrimidinone antianginal agents. Pfizer, Peter C Richardson, Gregg C Benson, Robert T Ronau, December 21, 1993: US05272147 (29 worldwide citation)

Compounds of the formula ##STR1## and pharmaceutically acceptable salts thereof are selective cGMP PDE inhibitors which are useful in the treatment of such diseases and adverse conditions as angina, hypertension, congestive heart failure, reduced blood vessel patency, peripheral vascular disease, st ...