1
Johannes H W Leuvering: Metal sol particle immunoassay. Akzona Incorporated, Robert H Falk, Charles A Wendel, Frank W Young, February 2, 1982: US04313734 (311 worldwide citation)

A method, test kit and labeled component for the detection and/or determination of one or more components of the reaction between a specific binding protein and the corresponding bindable substance, in which one or more labelled components are used, that are obtained by coupling particles of a dispe ...


2
Randall T Sparks, Edward J Geoghegan: Controlled release powder and process for its preparation. Elan Corporation, Robert H Falk, Henry Croskell, July 10, 1990: US04940588 (156 worldwide citation)

A controlled release powder containing discrete micro-particles for use in edible, pharmaceutical and other controlled release compositions is disclosed. The micro-particles have an average size in the range of from 0.1 to 125 .mu.m. Each of the micro-particles is in the form of a micromatrix of an ...


3
Thomas C J Gribnau, Frits Roeles, Johannes H W Leuvering: Application of water-dispersible hydrophobic dyes or pigments as labels in immunoassays. Akzona Incorporated, Robert H Falk, Charles A Wendel, Francis W Young, February 15, 1983: US04373932 (146 worldwide citation)

Processes, reagents and test kits for the qualitative and/or quantitative determination of an immunochemically reactive component, in which one or more labelled components are used, that are obtained by direct or indirect coupling of such a component or components to particles of an aqueous dispersi ...


4
Carl B Linnecke, Daniel Wong: Method and apparatus for specific binding substances. Akzona Incorporated, Robert H Falk, Charles A Wendel, Francis W Young, December 23, 1980: US04240751 (113 worldwide citation)

A novel combination and a method are disclosed for detecting and measuring a predetermined substance capable of being specifically bound. The combination comprises a novel adapter which eliminates contact of a light conducting and receiving probe with the sample. The novel combination comprises (1) ...


5
Edward J Geoghegan, Seamus Mulligan, Donald E Panoz: Controlled absorption diltiazem formulation for once-daily administration. Elan Corporation, Marla J Church, Robert H Falk, January 16, 1990: US04894240 (80 worldwide citation)

A diltiazem pellet formulation for oral administration comprises a core of diltiazem or a pharmaceutically acceptable salt thereof in association with an organic acid, and a multi-layer membrane surrounding the core and containing a major proportion of a pharmaceutically acceptable film-forming, wat ...


6
Donald Panoz, Gilbert Corneille: Processes for the preparation of delayed action and programmed release pharmaceutical forms and medicaments obtained thereby. Elan, Robert H Falk, Henry Croskell, Harry J Watson, September 24, 1991: US05051262 (76 worldwide citation)

Specifically, the present invention relates to processes for preparing delayed action galenic forms. The process is characterized in that the application solutions of excipients, coatings and active constituents are adjusted to a desired pH. The independence of the rate of dissolution of a controlle ...


7
Roy F Schall Jr, Stephen J Lewis: Glass support coated with synthetic polymer for bioprocess. Akzona Incorporated, Robert H Falk, Charles A Wendel, Francis W Young, November 2, 1982: US04357142 (67 worldwide citation)

A new and useful process is disclosed for manufacturing a device for use in a bioprocess, comprising: (a) providing solid support means insoluble in water or organic solvent solutions; (b) coating said solid support means with organic-solvent based polymeric film means capable of applying one or mor ...


8
Johan R A Simoons: Compositions containing alkali metal sulfate salts of conjugated estrogens and antioxidants as stabilizers. Akzona Incorporated, Robert H Falk, Charles A Wendel, Francis W Young, May 15, 1979: US04154820 (66 worldwide citation)

A new and remarkably stable synthesized conjugated estrogen composition comprising one or more selected alkali metal synthetic conjugated estrogen sulfate salts and an effective amount of one or more suitable antioxidants has been found for use in novel and stable therapeutic preparations of a pH of ...


9
Lamar C Kendell: Prefilled sterilant fluid releasable coupling connector apparatus for catheter applications. DelMed, Robert H Falk, Henry Croskell, Tom R Vestal, March 2, 1993: US05190534 (63 worldwide citation)

A releasable coupling connector apparatus for catheter applications is provided wherein the connector is partially filled wtih anti-infective solution during manufacture and capped so that a patient or medical technician does not have the task of opening the fluid pathway and introducing the anti-in ...


10
Nancy Ann Posch: Continuous flow apparatus for biological testing. Akzona Incorporated, Robert H Falk, Francis W Young, Phillip M Pippenger, October 11, 1977: US04053284 (61 worldwide citation)

A test apparatus for conducting diagnostic tests on body fluids, said apparatus having (1) a reaction vessel containing immunochemical test reagents supported as on beads and (2) a washing means cooperating with the reaction vessel, said washing means supplying washing fluid for the reaction vessel. ...