1
Robert E Fischell: Plural module medication delivery system. The Johns Hopkins University, Robert E Archibald, Howard W Califano, January 22, 1985: US04494950 (1130 worldwide citation)

A system consisting of a multiplicity of separate modules which collectively perform a useful biomedical purpose; the modules communicating with each other without the use of interconnecting wires. All modules may be intracorporeal or body mounted extracorporeal or some modules may be intracorporeal ...


2
Robert E Fischell: Implantable, programmable medication infusion system. The Johns Hopkins University, Robert E Archibald, Marc A Block, Samuel L Sachs, February 15, 1983: US04373527 (691 worldwide citation)

An implantable programmable medication infusion system comprises an implantable portion (2) having a medication reservoir (10) at below body pressure and isolated at its input from the body in which it is implanted by an antechamber (8) the pressure integrity of which is checked before filling the m ...


3
Robert E Fischell, Peter C Lord: Refillable medication infusion apparatus. The Johns Hopkins University, Robert E Archibald, Howard W Califano, March 4, 1986: US04573994 (494 worldwide citation)

Apparatus and method for filling, or refilling, the internal reservoir of a medication infusion system, wherein filling or refilling is permitted only when a means for injecting medication is properly positioned relative to the reservoir. Prior to filling or refilling, a pressure integrity check can ...


4
Jeffery C Lesho, Arthur F Hogrefe: Ingestible size continuously transmitting temperature monitoring pill. The Johns Hopkins University, Robert E Archibald, Howard W Califano, July 4, 1989: US04844076 (430 worldwide citation)

A temperature responsive transmitter is disclosed. The transmitter utilizes a unique circuit design that allows encapsulation in an ingestible size capsule. The inventive circuit design uses a one transistor inverting amplifier with a tank circuit forming the link between the transistor's collector ...


5
Robert E Fischell: Programmable control means for providing safe and controlled medication infusion. The Johns Hopkins University, Robert E Archibald, Howard W Califano, March 15, 1988: US04731051 (412 worldwide citation)

An implantable programmable infusion pump (IPIP) is disclosed and generally includes: a fluid reservoir filled with selected medication; a pump for causing a precise volumetric dosage of medication to be withdrawn from the reservoir and delivered to the appropriate site within the body; and, a contr ...


6
Arthur F Hogrefe, Wade E Radford: Coherent inductive communications link for biomedical applications. The Johns Hopkins University, Robert E Archibald, Howard W Califano, December 31, 1985: US04561443 (258 worldwide citation)

A two-way coherent inductive communications link between an external transceiver and an internal transceiver located in a biologically implanted programmable medical device. Digitally formatted command data and programming data is transmitted to the implanted medical device by frequency shift keying ...


7
Quentin E Dolecek: Memory-linked wavefront array processor. The Johns Hopkins University, Robert E Archibald, Howard W Califano, January 19, 1988: US04720780 (219 worldwide citation)

A Memory-Linked Wavefront Array Processor (MWAP) is disclosed which computes a broad range of signal processing, scientific and engineering problems at ultra-high speed. The memory-linked wavefront array processor is an array of identical programmable processing elements linked together by dual-port ...


8
Arnold L Newman: Optimized capacitive sensor for chemical analysis and measurement. The Johns Hopkins University, Robert E Archibald, Howard W Califano, April 18, 1989: US04822566 (219 worldwide citation)

An apparatus for detecting the presence and/or measuring the concentration of an analyte in the fluid medium is disclosed. The apparatus relies on biospecific binding between a biochemical binding system and the analyte to change the dielectric properties of a capacitive affinity sensor. The biologi ...


9
Robert E Fischell, William R Powell: Epidural lead electrode and insertion needle. The Johns Hopkins University, Robert E Archibald, Samuel L Sachs, February 27, 1979: US04141365 (198 worldwide citation)

Tissue stimulation apparatus for positive positioning of an electrode-bearing lead proximous to tissue which is to be stimulated electrically, the invention particularly includes a body penetration and insertion assembly which carries an elongated flexible strip of physiologically inert plastic mate ...


10
Arnold L Newman: Implantable helical cuff. The Johns Hopkins University, Robert E Archibald, November 21, 1989: US04881939 (184 worldwide citation)

The invention concerns an implantable, inflatable helical cuff which is wrapped about a tubular body member such as a nerve cord, esophagus, colon, intestine, or blood vessel in a pressure transferring relationship. The cuff may be completely inflated to function as an occluder, or partially inflate ...