1
Cheng Dai, Ding Qiang, Han Dong, Gray Nathanael Schiander, Zhang Guobao: 6-substituted anilino purines as rtk inhibitors. Irm, Cheng Dai, Ding Qiang, Han Dong, Gray Nathanael Schiander, Zhang Guobao, REID Scott W, February 24, 2005: WO/2005/016528 (62 worldwide citation)

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with cSRC, Lck, FGFR3, Flt3, TrkB, Bmx, and/or PFGFR&agr; kinase activity.


2
Epple Robert, Cow Christopher, Xie Yongping, Wang Xing, Russo Ross, Azimioara Mihai, Saez Enrique: Compounds and compositions as ppar modulators. Irm, Epple Robert, Cow Christopher, Xie Yongping, Wang Xing, Russo Ross, Azimioara Mihai, Saez Enrique, REID Scott W, December 8, 2005: WO/2005/116000 (54 worldwide citation)

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the Peroxisome Proliferator-Activated Receptor (PPAR) families, particularly the activity of PPAR.


3
Okram Barun, Ren Pingda, Gray Nathanael S: Pyrrolopyridine derivatives as protein kinase inhibitors. Irm, The Scripps Research Institute, Okram Barun, Ren Pingda, Gray Nathanael S, REID Scott W, November 23, 2006: WO/2006/124863 (51 worldwide citation)

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal act ...


4
Pan Shifeng, Gao Wenqi, Gray Nathanael S, Mi Yuan, Fan Yi: Immunosuppressant compounds and compositions. Irm, Pan Shifeng, Gao Wenqi, Gray Nathanael S, Mi Yuan, Fan Yi, REID Scott W, December 2, 2004: WO/2004/103306 (47 worldwide citation)

The present invention relates to immunosuppressant, process for their production, their uses and pharmaceutical compositions containing them. The invention provides a novel class of compounds useful in the treatment or prevention of diseases or disorders mediated by lymphocyte interactions, particul ...


5
Choi Ha Soon, Wang Zhicheng, Gray Nathanael Schiander, Gu Xiang Ju, He Xiaohui, He Yun, Jiang Tao, Liu Yi, Richmond Wendy, Sim Taebo, Yang Kunyong: Compounds and compositions as protein kinase inhibitors. Irm, Choi Ha Soon, Wang Zhicheng, Gray Nathanael Schiander, Gu Xiang Ju, He Xiaohui, He Yun, Jiang Tao, Liu Yi, Richmond Wendy, Sim Taebo, Yang Kunyong, REID Scott W, September 1, 2005: WO/2005/080393 (43 worldwide citation)

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal act ...


6
Gao Wenqi, Wan Yongqin, Jiang Jiqing, Fan Yi, Gray Nathanael S, Pan Shifeng: Immunosuppressant compounds and compositions. Irm, Gao Wenqi, Wan Yongqin, Jiang Jiqing, Fan Yi, Gray Nathanael S, Pan Shifeng, REID Scott W, March 1, 2007: WO/2007/024922 (42 worldwide citation)

The present invention relates to immunosuppressants, processes for their production, their uses and pharmaceutical compositions containing them. The invention provides a novel class of compounds useful in the treatment or prevention of diseases or disorders mediated by lymphocyte interactions, parti ...


7
Pan Shifeng, Gray Nathanael S, Mi Yuan, Fan Yi, Gao Wenqi: Immunosuppressant compounds and compositions. Irm, Pan Shifeng, Gray Nathanael S, Mi Yuan, Fan Yi, Gao Wenqi, REID Scott W, December 29, 2004: WO/2004/113330 (39 worldwide citation)

The present invention relates to immunosuppressant, process for their production, their uses and pharmaceutical compositions containing them. The invention provides a novel class of compounds useful in the treatment or prevention of diseases or disorders mediated by lymphocyte interactions, particul ...


8
Zhang Qiong, Gray Nathanael S, Liu Yi, Ding Qiang, Uno Tetsuo: Protein kinase inhbitors. Irm, Zhang Qiong, Gray Nathanael S, Liu Yi, Ding Qiang, Uno Tetsuo, REID Scott W, May 18, 2007: WO/2007/056151 (37 worldwide citation)

The invention provides disubtituted pyrimidine or pyridine compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that i ...


9
Chen Shuibing, Ding Sheng, Yan Feng, Schultz Peter G: Compounds that maintain pluripotency of embryonic stem cells. Irm, The Scripps Research Institute, Chen Shuibing, Ding Sheng, Yan Feng, Schultz Peter G, REID Scott W, December 21, 2006: WO/2006/135824 (36 worldwide citation)

The present invention relates to methods and compositions for culturing embryonic stem (ES) cells. The methods relate to growing the ES cells in the presence of small molecules of formula (I) that maintain the pluripotency/self-renewal of the cells without feeder cells and LIF in serum-free conditio ...


10
Hong Jiyong, Gray Nathanael S, Schultz Peter: Compounds and compositions as inducers of keratinocyte differentiation. Irm, The Scripps Research Institute, Hong Jiyong, Gray Nathanael S, Schultz Peter, REID Scott W, November 17, 2005: WO/2005/107760 (35 worldwide citation)

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to induce undifferentiated keratinocytes to differentiate into terminally differentiated keratinocytes. The invention further provides compounds for the treatment of diseases o ...