1
Anderson J Christopher, Wu Ning, Santoro Stephen, Schultz Peter G: Compositions of orthogonal lysyl-trna and aminoacyl-trna synthetase pairs and uses thereof. The Scripps Research Institute, Anderson J Christopher, Wu Ning, Santoro Stephen, Schultz Peter G, QUINE Jonathan Alan, March 3, 2005: WO/2005/019415 (104 worldwide citation)

Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal lysyl-tRNAs, orthogonal lysyl-aminoacyl-tRNA synthetases, and orthogonal pairs of lysyl-tRNAs/synthetases, which incorporate homoglutamines into proteins are provided in response to a four base ...


2
Chin Jason W, Cropp Ashton T, Anderson Christopher J, Schultz Peter G: Expanding the eukaryotic genetic code. The Scripps Research Institute, Chin Jason W, Cropp Ashton T, Anderson Christopher J, Schultz Peter G, QUINE Jonathan Alan, November 4, 2004: WO/2004/094593 (86 worldwide citation)

This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural a ...


3
Schultz Peter G, Wang Lei: Site specific incorporation of keto amino acids into proteins. The Scripps Research Institute, Schultz Peter G, Wang Lei, QUINE Jonathan Alan, April 29, 2004: WO/2004/035743 (78 worldwide citation)

Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases, which incorporate keto amino acids into proteins are provided. Methods for identifying these orthogonal ...


4
Bock Larry, Daniels R Hugh, Empedocles Stephen, Niu Chumming, Owicki John C, Sahi Vijendra, Chow Calvin, Pontis George: Nano-chem-fet based biosensors. Nanosys, Bock Larry, Daniels R Hugh, Empedocles Stephen, Niu Chumming, Owicki John C, Sahi Vijendra, Chow Calvin, Pontis George, QUINE Jonathan Alan, April 22, 2004: WO/2004/034025 (78 worldwide citation)

Methods of detecting a component of interest, a change in charge, a pH, a cellular response using nanosensors are provided. Nanosensors, including nanowires and nanowire arrays comprising functionalized and/or non-functionalized nanowires are provided. Nanosensors are used for detection in cellular ...


5
Pontis George, Stonas Walter, Chow Calvin, Parce Wallace J, Pan Yaoling, Romano Linda T, Mostarshed Shahriar: Planar nanowire based sensor elements, devices, systems and methods for using and making same. Nanosys, Pontis George, Stonas Walter, Chow Calvin, Parce Wallace J, Pan Yaoling, Romano Linda T, Mostarshed Shahriar, QUINE Jonathan Alan, January 8, 2004: WO/2004/003535 (74 worldwide citation)

Sensor elements and devices that incorporate those elements are provided, where the sensor comprises a thin semiconductor nanowire (202) that is disposed upon, and integral to, an insulating substrate (204), where the nanowire (202) is electrically coupled to a sensing surface (210) that binds or ot ...


6
Scher Erik, Buretea Mihai A, Chow Calvin, Empedocles Stephen, Meisel Andreas, Parce J Wallace: Nanostructure and nanocomposite based compositions and photovoltaic devices. Nanosys, Scher Erik, Buretea Mihai A, Chow Calvin, Empedocles Stephen, Meisel Andreas, Parce J Wallace, QUINE Jonathan Alan, March 18, 2004: WO/2004/023527 (65 worldwide citation)

Nanocomposite photovoltaic devices are provided that generally include semiconductor nanocrystals as at least a portion of a photoactive layer. Photovoltaic devices and other layered devices that comprise core-shell nanostructures and/or two populations of nanostructures, where the nanostructures ar ...


7
Schultz Peter G, Wang Lei, Zhang Zhiwen: Glycoprotein synthesis. The Scripps Research Institute, Schultz Peter G, Wang Lei, Zhang Zhiwen, QUINE Jonathan Alan, April 29, 2004: WO/2004/035605 (64 worldwide citation)

Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a ...


8
Buretea Mihai, Empedocles Stephen, Niu Chunming, Scher Erik C: Nanocomposites. Nanosys, Buretea Mihai, Empedocles Stephen, Niu Chunming, Scher Erik C, QUINE Jonathan Alan, March 18, 2004: WO/2004/022637 (56 worldwide citation)

This invention provides composite materials comprising nanostructures (5,9) (e.g., nanowires, branched nanowires, nanotetrapods, nanocrystals, and nanoparticles). Methods and compositions for making such nanocomposites are also provided, as are articles (20-27, 30-40, 50-56) comprising such composit ...


9
Anderson J Christopher, Schultz Peter G: Compositions of orthogonal leucyl-trna and aminoacyl-trna synthetase pairs and uses thereof. The Scripps Research Institute, Anderson J Christopher, Schultz Peter G, QUINE Jonathan Alan, January 27, 2005: WO/2005/007870 (55 worldwide citation)

Compositions and methods of producing components of protein biosynthetic machinery that include leucyl orthogonal tRNAs, leucyl orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of leucyl tRNAs/synthetases are provided. Methods for identifying these orthogonal pairs are also provided along ...


10
Schultz Peter G, Wang Lei: Protein arrays. The Scripps Research Institute, Schultz Peter G, Wang Lei, QUINE Jonathan Alan, July 15, 2004: WO/2004/058946 (54 worldwide citation)

The invention provides proteins attached to solid supports, and methods of preparing such solid support-bound proteins are provided. The proteins are attached to solid supports by means of an unnatural amino acid incorporated into the protein, which unnatural amino acid includes a reactive group tha ...