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Tammy Burd Mehta, Anne R Kopf Sill, J Wallace Parce, Andrea W Chow, Luc J Bousse, Michael R Knapp, Theo T Nikiforov, Steve Gallagher: Manipulation of microparticles in microfluidic systems. Caliper Technologies, Matthew B Murphy, Donald R McKenna, Quine Intellectual Property Law Group P C, October 14, 2003: US06632655 (390 worldwide citation)

Arrays of flowable or fixed particle sets are used in microfluidic systems for performing assays and modifying hydrodynamic flow. Also provided are assays utilizing flowable or fixed particle sets within a microfluidic system, as well as kits, apparatus and integrated systems comprising arrays and a ...


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Erik Scher, Mihai A Buretea, Calvin Chow, Stephen Empedocles, Andreas Meisel, J Wallace Parce: Nanostructure and nanocomposite based compositions and photovoltaic devices. Nanosys, Quine Intellectual Property Law Group P C, Andrew L Filler, April 12, 2005: US06878871 (302 worldwide citation)

Nanocomposite photovoltaic devices are provided that generally include semiconductor nanocrystals as at least a portion of a photoactive layer. Photovoltaic devices and other layered devices that comprise core-shell nanostructures and/or two populations of nanostructures, where the nanostructures ar ...


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Michael Knapp, John Wallace Parce, Luc J Bousse, Anne R Kopf Sill: Microfluidic devices and methods for separation. Caliper Technologies, Matthew B Murphy, Angela P Horne, Quine Intellectual Property Law Group P C, September 3, 2002: US06444461 (231 worldwide citation)

Integrated systems, apparatus, software, and methods for performing biochemical analysis, including DNA sequencing, genomic screening, purification of nucleic acids and other biological components and drug screening are provided. Microfluidic devices, systems and methods for using these devices and ...


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J Wallace Parce, Theo T Nikiforov, Tammy Burd Mehta, Anne R Kopf Sill, Andrea W Chow, Michael R Knapp: Sequencing by incorporation. Caliper Technologies, Stacy Landry, Gary Baker, Quine Intellectual Property Law Group P C, September 2, 2003: US06613513 (198 worldwide citation)

Nucleotides and nucleotide analogs are used in various sequencing by incorporation/sequencing by synthesis methods. Nucleotide analogs comprising 3′-blocking groups are used to provide reversible chain-termination for sequencing by synthesis. Typical blocking groups include phosphate groups and carb ...


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Larry Bock, R Hugh Daniels, Stephen Empedocles: Nano-chem-FET based biosensors. Nanosys, Quine Intellectual Property Law Group P C, Andrew L Filler, December 4, 2007: US07303875 (173 worldwide citation)

Methods of detecting components of interest, e.g., nucleic acids and sugars, are provided. The methods comprise contacting one or more nanowires comprising a functional group with a sample containing the component or components of interest. In one embodiment, the functional group comprises a hairpin ...


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Stephen Empedocles, Larry Bock, Calvin Chow, Xianfeng Duan, Chungming Niu, George Pontis, Vijendra Sahi, Linda T Romano, David Stumbo: Methods of making, positioning and orienting nanostructures, nanostructure arrays and nanostructure devices. Nanosys, Andrew L Filler, Quine Intellectual Property Law Group P C, November 8, 2005: US06962823 (167 worldwide citation)

Nanostructure manufacturing methods and methods for assembling nanostructures into functional elements such as junctions, arrays and devices are provided. Systems for practicing the methods are also provided.


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Scott Hirsch: Method and apparatus for improved information representation. Surfnotes, Stephen J LeBlanc, Quine Intellectual Property Law Group P C, August 2, 2005: US06924828 (151 worldwide citation)

A information search and navigation system indexes, categorizes and condenses data from text or other documents. In various embodiments, the invention further can utilize user information goals, document or website types and multi-page link path options that together provide a fast, multi-page Web n ...


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Christine Loehrlein, Dan Pollart, Thomas Shaler, Kathy Stephens, Yuping Tan, Linda Wong, Joseph Monforte: Methods for analysis of gene expression. Althea Technologies, Angela P Horne, Quine Intellectual Property Law Group P C, September 9, 2003: US06618679 (150 worldwide citation)

This invention provides methods, compositions and kits for gene expression analysis and gene expression profiling. The methods of the invention are highly sensitive; have a wide dynamic range; are rapid and inexpensive; have a high throughput; and allow the simultaneous differential analysis of a de ...