1
Benton A Durley III, James D Defreese, Carl W Merkh: Test card for performing assays. Abbott Laboratories, Wean Khing Wong, Priscilla E Porembski, December 24, 1991: US05075077 (164 worldwide citation)

A semi-automated biological sample analyzer and subsystems are provided to simultaneously perform a plurality of enzyme immuno assays for human IgE class antibodies specific to a panel of preselected allergens in each of a plurality of biological samples. A carousel is provided to position and hold ...


2
Omar S Khalil, Charles F Hanna, Thomas F Zurek, Denise A Grigalauski: Immunoassay device with liquid transfer between wells by washing. Abbott Laboratories, Priscilla E Porembski, April 9, 1991: US05006309 (114 worldwide citation)

A disposable device suitable for performing automated solid-state diagnostic assays which employs microparticles to complex an analyte and where the microparticle complex becomes retained and immobilized on a fibrous matrix such that the presence of analyte on the microparticles can be detected by a ...


3
Omar S Khalil, Thomas F Zurek, Kevin R Genger, Curtis J Pepe, Yi Her Jou, Stephen M Cotter: Method and apparatus for heterogeneous chemiluminescence assay. Abbott Laboratories, Priscilla E Porembski, Daniel W Collins, February 18, 1992: US05089424 (105 worldwide citation)

Apparatus and method for performing a chemiluminescence assay involving the immobilization of a chemiluminescent reaction complex to a solid, porous element. The solid, porous element is preferably treated to provide an immobilizing interaction with the chemiluminescent reaction complex wherein the ...


4
Emerson W Chan, Werner Schulze, William G Robey, Brian P Braun, Cynthia K Daluga, Andreas A Kapsalis, Kevin M Knigge, John E Stephens, Joseph J Stojak II, David S Vallaris, Benton A Durley deceased, James D Defreese, Carl W Merkh: Multilayer solid phase immunoassay support and method of use. Abbott Laboratories, Priscilla E Porembski, Frank S Ungemach, June 9, 1992: US05120662 (96 worldwide citation)

An immunoassay which is capable of simultaneously detecting any desired number of antigens of one infectious agent, or combinations of antigens of several infectious agents, or any desired number of immunoglobulins of one infectious agent, or combinations of immunoglobulins of several infectious age ...


5
Diane L Aunet, Gradimir G Gerogevich, Tzyy Wen Jeng, Gary M Oosta, Neal A Siegel: Methods and devices for the separation of plasma or serum from whole blood. Abbott Laboratories, Priscilla E Porembski, Daniel W Collins, Thomas D Brainard, June 12, 1990: US04933092 (85 worldwide citation)

A device and method for permitting the separation of plasma or serum from whole blood. The device comprises a matrix of hydrophilic sintered porous material to which at least one red blood cell agglutinating agent has been applied. According to a first method of using the device, a sample of whole b ...


6
Phillip G Mattingly, Larry G Bennett: Chemiluminescent acridinium salts. Abbott Laboratories, Priscilla E Porembski, November 21, 1995: US05468646 (80 worldwide citation)

Acridinium sulfonylamides and isomers, such as phenanthridinium sulfonylamides, may be employed in applications including chemiluminmescent immunoassays. Methods for synthesis of these compounds include contacting an amine with a sulfonylhalide to form a sulfonamide and acylating with an activated c ...


7
Phillip G Mattingly: 5(6)-methyl substituted fluorescein derivatives. Abbott Laboratories, Priscilla E Porembski, October 4, 1994: US05352803 (80 worldwide citation)

5(6)-methyl substituted fluorescein derivatives and a process for producing 5(6)-methyl substituted derivatives. Also provided are methods for these utilizing these derivatives as indicator reagents in assays for analytes, indicator reagents which comprise specific binding members attached to these ...


8
Omar S Khalil, Charles F Hanna, Denise G Huff, Thomas F Zurek: Device for performing solid-phase diagnostic assay. Abbott Laboratories, Frank S Ungemach, Priscilla E Porembski, Daniel W Collins, September 14, 1993: US05244630 (66 worldwide citation)

A disposable device suitable for performing automated solid-phase diagnostic assays which employs microparticles to complex an analyte and where the microparticle complex becomes retained and immobilized on a fibrous matrix such that the presence of analyte on the microparticles can be detached by o ...


9
Kenneth P English, Stanley E Micek III, Michael B O Connell, Edward S Tripp: Diagnostic testing device. Abbott Laboratories, Priscilla E Porembski, Daniel W Collins, Thomas M Breininger, September 22, 1992: US05149505 (55 worldwide citation)

A diagnostic testing device is disclosed. The testing device includes a base member and a cover member which defines an opening for the reception of a liquid specimen. A distribution wheel delivers portions of the specimen to antibiotic units which are circumferentially spaced. Indicator units are i ...


10
Phillip G Mattingly, Larry G Bennett: Chemiluminescent acridinium salts. Abbott Laboratories, Priscilla E Porembski, August 6, 1996: US05543524 (51 worldwide citation)

Acridinium sulfonylamides and isomers, such as phenanthridinium sulfonylamides, may be employed in applications including chemiluminmescent immunoassays. Methods for synthesis of these compounds include contacting an amine with a sulfonylhalide to form a sulfonamide and acylating with an activated c ...