1
John R Peery, Keith E Dionne, James B Eckenhoff, Felix A Landrau, Scott D Lautenbach, Judy A Magruder, Jeremy C Wright: Sustained delivery of leuprolide using an implantable system. Alza Corporation, Pauline A Clarke, Mary Ann Dillahunty, Steven F Stone, March 17, 1998: US05728396 (288 worldwide citation)

The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable ...


2
Guohua Chen, Scott D Lautenbach, Keith E Dionne, Scott D Jordan, Steve A Berry, Craig I Rodenberger, Rupal Ayer: Osmotic delivery system, osmotic delivery system semimpermeable body assembly, and method for controlling delivery rate of beneficial agents from osmotic delivery systems. Alza Corporation, Cindy A Lynch, Pauline A Clarke, D Byron Miller, September 11, 2001: US06287295 (102 worldwide citation)

Osmotic delivery system semipermeable body assemblies that control the delivery rate of a beneficial agent from an osmotic delivery system incorporating one of the semipermeable body assemblies. A semipermeable body assembly or plug includes a semipermeable body which is positionable in an opening o ...


3
Craig R Davis, John R Peery: Implanter device for subcutaneous implants. Alza Corporation, Steven F Stone, Pauline A Clarke, Cindy A Lynch, February 20, 2001: US06190350 (92 worldwide citation)

An implanter for inserting subcutaneous implants includes a handle for grasping the implanter during implantation, a hollow cannula receiving the implant, and a rod for releasing the implant from the cannula. The rod is longitudinally fixed within the handle while the cannula slides over the rod to ...


4
John R Peery, Keith E Dionne, James B Eckenhoff, Felix A Landrau, Scott D Lautenbach, Judy A Magruder, Jeremy C Wright: Sustained delivery of an active agent using an implantable system. Alza Corporation, Pauline A Clarke, Mary Ann Dillahunty, May 28, 2002: US06395292 (91 worldwide citation)

The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable ...


5
Rupal Ayer: Osmotic delivery system with membrane plug retention mechanism. ALZA Corporation, Cindy A Lynch, Pauline A Clarke, D Byron Miller, August 7, 2001: US06270787 (78 worldwide citation)

An osmotic delivery system has a membrane plug retention mechanism which can also be used to control the delivery rate of a beneficial agent from the osmotic delivery system. The osmotic delivery device includes an implant capsule containing a beneficial agent and an osmotic agent. Holes are formed ...


6
Guohua Chen, Scott Lautenbach, Keith Dionne, Lawton Hom: Beneficial agent delivery system with membrane plug and method for controlling delivery of beneficial agents. ALZA Corporation, Cindy A Lynch, Steven F Stone, Pauline A Clarke, September 5, 2000: US06113938 (72 worldwide citation)

An osmotic delivery system for controlled delivery of a beneficial agent includes an implant capsule containing a beneficial agent and an osmotic agent which swells on contact with water causing the release of the beneficial agent over time. The osmotic delivery system has a membrane plug which allo ...


7
Cynthia L Stevenson, Steven J Prestrelski: Non-aqueous polar aprotic peptide formulations. ALZA Corporation, Mary Ann Dillahunty, Steven F Stone, Pauline A Clarke, September 26, 2000: US06124261 (62 worldwide citation)

This invention relates to stable non-aqueous polar aprotic formulations of peptide compounds. These stable formulations comprise peptide in non-aqueous polar aprotic solvent. They may be stored at elevated temperatures for long periods of time and are especially useful in implantable delivery device ...


8
Seth R Abbott: Mixed phase chromatographic compositions. Varian Associates, Stanley Z Cole, Pauline A Clarke, November 3, 1981: US04298500 (62 worldwide citation)

The mixed phase packing material of this invention, enables rapid separation of multi-sited biopolymers. This separation is achieved by "tailoring" the distance between organo-silyl groups covalently bonded to the rigid support at the Angstrom distance needed for reversible separation of the biopoly ...


9
John R Peery, Keith E Dionne, James B Eckenhoff deceased, Felix A Landrau, Scott D Lautenbach, Judy A Magruder, Jeremy C Wright: Sustained delivery of an active agent using an implantable system. ALZA Corporation, Mary Ann Dillahunty, Pauline A Clarke, Steven F Stone, December 5, 2000: US06156331 (59 worldwide citation)

The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable ...


10
Cynthia L Stevenson, Steven J Prestrelski: Non-aqueous polar aprotic peptide formulations. ALZA Corporation, Pauline A Clarke, Mary Ann Dillahunty, Steven F Stone, May 22, 2001: US06235712 (50 worldwide citation)

This invention relates to stable non-aqueous polar aprotic formulations of peptide compounds. These stable formulations comprise peptide in non-aqueous polar aprotic solvent. They may be stored at elevated temperatures for long periods of time and are especially useful in implantable delivery device ...