1
Marvin J Slepian: Sensing, interrogating, storing, telemetering and responding medical implants. Endoluminal Therapeutics, Pabst Patent Group, October 12, 2004: US06802811 (365 worldwide citation)

Implants and implants, including sensors responsive to pressure, fluid flow, concentration of analytes, pH and other variables, including a feedback loop and means for modifying the implant after placement in a patient in response to measurements made using the sensors, have been developed. These ar ...


2
Simon F Williams, David P Martin, Frank A Skraly: Medical devices and applications of polyhydroxyalkanoate polymers. Metabolix, Pabst Patent Group, January 4, 2005: US06838493 (300 worldwide citation)

Devices formed of or including biocompatible polyhydroxyalkanoates are provided with controlled degradation rates, preferably less than one year under physiological conditions. Preferred devices include sutures, suture fasteners, meniscus repair devices, rivets, tacks, staples, screws (including int ...


3
David P Martin, Frank Skraly, Simon F Williams: Polyhydroxyalkanoate compositions having controlled degradation rates. Metabolix, Pabst Patent Group, March 15, 2005: US06867248 (224 worldwide citation)

Biocompatible polyhydroxyalkanoate compositions with controlled degradation rates have been developed. In one embodiment, the polyhydroxyalkanoates contain additives to alter the degradation rates. In another embodiment, the polyhydroxyalkanoates are formed of mixtures of monomers or include pendant ...


4
Julie Straub, Howard Bernstein, Donald E Chichering III, Sarwat Khattak, Greg Randall: Porous drug matrices and methods of manufacture thereof. Acusphere, Pabst Patent Group, August 23, 2005: US06932983 (126 worldwide citation)

Drugs, especially low aqueous solubility drugs, are provided in a porous matrix form, preferably microparticles, which enhances dissolution of the drug in aqueous media. The drug matrices preferably are made using a process that includes (i) dissolving a drug, preferably a drug having low aqueous so ...


5
James N Campbell: Treatment of pain. Arcl, Pabst Patent Group, February 19, 2008: US07333857 (124 worldwide citation)

The method disclosed herein entails spinal cord stimulation via electrodes placed directly into the dorsal horn, dorsal column, spinothalamic tract, nucleus cuneatus, nucleus gracilis, spinal tract of V, or spinal nucleus of V (nucleus caudalis) depending on the source of pain. This “intramedullary” ...


6
Mark R Goodwin: Intraosteal ultrasound during surgical implantation. Cutting Edge Surgical, Pabst Patent Group, February 1, 2005: US06849047 (116 worldwide citation)

IntraOsteal UltraSound (IOUS) is the use of acoustical energy to facilitate “real-time” manipulation and navigation of a device for intraosseous placement of synthetic or biologic implants and to diagnose the condition of the tissue into which the implant is being placed. Representative applications ...


7
Jeffrey A Hubbell, Marcus Textor, Donald L Elbert, Stephanie Finken, Rolf Hofer, Nicholas D Spencer, Laurence Ruiz Taylor: Multifunctional polymeric surface coatings in analytic and sensor devices. Eidgenossische Technische Hochschule Zurich, Universitat Zurich, Pabst Patent Group, April 26, 2005: US06884628 (110 worldwide citation)

Multifunctional, polyionic copolymers with molecular architectures and properties optimized for specific applications are synthesized on/or applied to substrate surfaces for analytical and sensing purposes. The coatings are particularly useful for suppression of non-specific interaction, adsorption ...


8
Simon F Williams, David P Martin, Frank A Skraly: Medical devices and applications of polyhydroxyalkanoate polymers. Metabolix, Pabst Patent Group, March 15, 2005: US06867247 (103 worldwide citation)

Devices formed of or including biocompatible polyhydroxyalkanoates are provided with controlled degradation rates, preferably less than one year under physiological conditions. Preferred devices include sutures, suture fasteners, meniscus repair devices, rivets, tacks, staples, screws (including int ...


9
Jane Hirsh, Alexander M Kibanov, Timothy M Swager, Stephen L Buchwald, Whe Yong Lo, Alison B Fleming, Roman V Rariy: Abuse-deterrent pharmaceutical compositions of opiods and other drugs. Collegium Pharmaceutical, Pabst Patent Group, July 15, 2008: US07399488 (96 worldwide citation)

An abuse-deterrent pharmaceutical composition has been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opiods. In the preferred embodiment, a drug is modified to increase its lipophilicity. In preferred embodiments the modified drug is homogeneously d ...


10
David P Martin, Frank Skraly, Simon F Williams: Polyhydroxyalkanoate compositions having controlled degradation rates. Metabolix, Pabst Patent Group, December 7, 2004: US06828357 (81 worldwide citation)

Biocompatible polyhydroxyalkanoate compositions with controlled degradation rates have been developed. In one embodiment, the polyhydroxyalkanoates contain additives to alter the degradation rates. In another embodiment, the polyhydroxyalkanoates are formed of mixtures of monomers or include pendant ...