1
Eric First, M.D.
Eric R First: Application of botulinum toxin to the management of neurogenic inflammatory disorders. Thomas J Nutter McClennen & Fish Engellenner, May 16, 2000: US06063768 (149 worldwide citation)

The present invention provides a method for the use of at least one serotype or a combination of serotypes of Botulinum neurotoxin either alone or in combination with other peptides or fusion proteins, that when administered in a safe and effective amount, antagonize and therefore decrease or block ...


2
Eric First, M.D.
L Bruce Pearce, Eric R First: Compositions and methods for chemodenervation using neurotoxins. Thomas J Engellenner, Nutter McClennen & Fish, July 11, 2000: US06087327 (34 worldwide citation)

The compositions and methods disclosed herein utilize admixtures of neurotoxins to cause denervation which is unexpectedly more localized and of longer duration than otherwise occurs with single neurotoxins. The compositions and methods of the invention utilize neurotoxin admixtures calibrated in me ...


3
Gary B Robinson: Automated collaborative filtering in world wide web advertising. Athenium L L C, Nutter McClennen & Fish, June 29, 1999: US05918014 (812 worldwide citation)

On the World Wide Web, and other interactive media, it is possible to show different ads to different people who are simultaneously viewing the same content. This invention is based on the fact that people who have shown a tendency for similar likes and dislikes in the past will show a tendency for ...


4
Thomas A Wrublewski, Kevin M Allaire, William Frey, Kevin Lemire, Paul C Nardella Sr: Seal & cut electrosurgical instrument. Medical Scientific, Nutter McClennen & Fish, January 16, 2001: US06174309 (699 worldwide citation)

An electrosurgical instrument has a handle and a body which position and close a jaw about a tissue site for simultaneously cutting and sealing relatively large tissue structures. The jaw includes an electrosurgical cutting member, which may be a blade or wire, against which tissue is biased along a ...


5
Paul C Nardella: Impedance feedback electrosurgical system. Medical Scientific, Nutter McClennen & Fish, February 3, 1998: US05713896 (579 worldwide citation)

An impedance feedback electrosurgical system is useful with electrosurgical tools to maintain a substantially constant level of current within the tissue in contact with the tool. The system comprises active and return electrodes associated with an electrosurgical tool, an impedance monitoring devic ...


6
James Coleman, Christy Cummins, Chris Martin, Thomas Anthony, Sean Morris: Surgical staples and methods for stapling. Nutter McClennen & Fish, September 9, 2003: US06616686 (458 worldwide citation)

A surgical staple is provided having a base portion and a respective leg extending from each end of the base portion and terminating at a free end. The base portion is deformable to bring the free ends of the legs together to penetrate a liquid-carrying vessel at the site of a puncture and hold the ...


7
Kevin S Weadock: Composite staple for completing an anastomosis. Ethicon, Nutter McClennen & Fish, October 7, 2003: US06629988 (456 worldwide citation)

An anastomosis staple comprising of a plurality of vessel engaging members and a binding structure holding the vessel engaging members together is described. The binding structure has at least one bioabsorbable element. The binding structure is rigid enough to allow for deployment and quickly resorb ...


8
Mark S Ortiz, Frederick E Shelton IV: Surgical fastener and cutter with single cable actuator. Ethicon Endo Surgery, Nutter McClennen & Fish, August 18, 2009: US07575144 (443 worldwide citation)

Methods and devices are provided for controlling rotation and actuation of an end effector on a surgical fastening device. In an exemplary embodiment, a single cable actuator is provided and is movable between a first position, in which it is effective to rotate an end effector without actuating (i. ...


9
Paul C Nardella: Electrosurgical cutting tool. Medical Scientific, Nutter McClennen & Fish, September 9, 1997: US05665085 (436 worldwide citation)

An electrosurgical tool comprises a retractable cutting element moveable along a linear cutting path and an electrical energy supply source which communicates electrical energy (e.g., radio frequency energy) through the cutting element and to tissue adjacent the cutting element. The cutting element ...


10
Christy Cummins: Surgical stapling device and method. Nutter McClennen & Fish, March 7, 2006: US07008435 (434 worldwide citation)

A surgical stapling device is provided having an elongate housing and a surgical staple slidable longitudinally within the housing towards a free forward end thereof, the staple having a back and two forwardly pointing legs. The housing contains a staple-firing mechanism for driving the staple towar ...



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