Richard C Hevey, Mark K Malmros: Methods for the detection and determination of ligands. Calbiochem Behring, Natalie Jensen, October 14, 1980: US04228237 (117 worldwide citation)

A method for determining the presence of a ligand in a liquid medium which utilizes enzyme labeled avidin and biotin labeled reagent in a specific binding process wherein the ligand to be detected is contacted with an insoluble phase containing specific binding substance for the ligand. Various prot ...

John K Pollard Jr: Material and method for removing immunoglobulins from whole blood. American Hoechst Corporation, Natalie Jensen, Jerome Rosenstock, James R Cartiglia, August 7, 1984: US04464165 (24 worldwide citation)

An immunoadsorbent material comprising inactivated, protein-A bearing Staphlococcus aureus immobilized in a polymeric matrix is used to remove IgG immunoglobulins and immune complexes from whole blood.

Stephen R Coates, Walter L Binder: Enzyme/immunofluorescent assay for autoantibodies. American Hoechst Corporation, James R Cartiglia, Natalie Jensen, December 11, 1984: US04487830 (22 worldwide citation)

A method for the determination of autoantibody in a test sample comprises contacting a substrate for the autoantibody with sample; treating the contacted substrate with labeled antihuman antibody selected from (1) a mixture comprising enzyme labeled antihuman antibody and fluorescent labeled antihum ...

Stephen R Coates: Erythrocyte preparations and use thereof in hemagglutination tests. American Hoechst Corporation, Natalie Jensen, September 6, 1983: US04403037 (19 worldwide citation)

Erythrocytes are coated with specific hemagglutinating virus antigen and then treated to produce a stabilized, antigen coated erythrocyte preparation which is used in the determination of antibody in biological fluids.

Keith A M Walker: 1-[.beta.(R-thio)phenethyl]imidazoles and derivatives thereof. Syntex, Alan M Krubiner, Natalie Jensen, October 25, 1977: US04055652 (13 worldwide citation)

Novel 1-[.beta.-(R-thio)phenethyl]-imidazoles and the corresponding 1-[.beta.-(R-sulfinyl)phenethyl]imidazoles and 1-[.beta.-(R-sulfonyl)phenethyl]imidazoles wherein R is alkyl, alkenyl, aralkenyl, substituted aralkenyl, alkynyl, cycloalkyl, cycloalkyl alkyl, aralkyl, substituted aralkyl, aryl or su ...

Ray E T Pollard: Portable pocket for pocket watches. Natalie Jensen, November 20, 1979: US04174798 (11 worldwide citation)

A watch pocket for mounting on a belt includes a pair of pliable sheets shaped and secured together to form an upwardly opening pocket and a transverse belt receiving loop behind the pocket with a pair of vertical relief slits formed in the wall between the pocket and loop to provide relief of press ...

Philip J Beeby: Cephalosporin type antibacterials. Syntex, Natalie Jensen, William B Walker, September 28, 1976: US03983113 (11 worldwide citation)

3-[3-(1-Methyltetrazol-5-ylthio)-prop-1-(t)-enyl]-7.beta.-(.alpha.-substitu ted acetamido)-ceph-3-em-4-carboxylic acid; 7.beta.-(.alpha.-substituted acetamido)-3-[3-(1,2,4-triazol-5-ylthio)-prop-1-(t)-enyl]-ceph-3-em-4-carb oxylic acid derivatives and salts thereof; and ester intermediates and proce ...

Richard C Hevey, Mark K Malmros, Wayne W Petko: Method for terminating a peroxidase catalyzed reaction. Calbiochem Behring, Natalie Jensen, November 18, 1980: US04234680 (9 worldwide citation)

Addition of a low concentration of an alkali metal metabisulfite completely stops color development in a peroxidase-labeled immunoassay wherein the peroxidase catalyzed reaction comprises oxidation of an achromatic substrate to the corresponding chromatic product in the presence of a peroxide.

Ralph P McCroskey: Reagents for the determination of enzymes. American Hoechst Corporation, James R Cartiglia, Natalie Jensen, September 18, 1984: US04472499 (6 worldwide citation)

Assay reagents for the determination of enzymes such as .alpha.-amylase, .alpha.-glucosidase, .beta.-glucosidase, and acid and alkaline phosphatases are described. The reagents comprise a substrate capable of releasing the chromophore p-nitrophenol at a rate proportional to the amount of enzyme bein ...

Philip J Beeby: Cephalosporin type antibacterials. Syntex, Lawrence S Squires, William B Walker, Natalie Jensen, September 20, 1977: US04049806 (6 worldwide citation)

3-[3-(1-Methyltetrazol-5-ylthio)-prop-1-(t)-enyl]-7.beta.-(.alpha.-phenylac etamido)-ceph-3-em-4-carboxylic acid; 7.beta.-(.alpha.-phenylacetamido)-3-[3-(1,2,4-triazol-5-ylthio)-prop-1-(t) -enyl]-ceph-3-em-4-carboxylic acid derivatives and salts thereof; and intermediates and processes for preparing ...