1
Dieter Banauch, Wolfgang Brummer, Wolfgang Ebeling, Roland Helger, Norbert Hennrich, Hermann Lang: Enzymatic determination of glucose. Merck Patent Gesellschaft mit beschrankter Haftung, Millen Raptes & White, June 22, 1976: US03964974 (272 worldwide citation)

Glucose is rapidly ad quantitatively determined with an analytical agent containing glucose dehydrogenase having an activity of at least 2 .mu./mg and NADH.sub.2 oxidase activity less than 0.1%, a pyridine coenzyme, a buffer and mutarotase to increase spontaneous mutarotation of alpha-glucose to bet ...


2
Bernhard Horst, Esselborn Reiner, Hesse Reiner, Russmann Horst: Iron-containing mica flake pigments. Merck Patent Gesellschaft mit beschraenkter Haftung, Millen Raptes & White, December 16, 1975: US3926659 (86 worldwide citation)

Novel mica flake pigments optionally coated with TiO.sub.2, ZrO.sub.2 and/or the hydrates thereof, having a uniform iron-containing layer thereon consisting of an iron(III) oxide hydroxide, magnetite and/or the Fe.sub.2 O.sub.3 modifications obtained therefrom by annealing at a temperature below 1,1 ...


3
Hanns Ahrens, Clemens Rufer, Helmut Biere, Eberhard Schroder, Wolfgang Losert, Olaf Loge, Ekkehard Schillinger: 1,2-Biguanides. Schering Aktiengesellschaft, Millen Raptes & White, June 1, 1976: US03960949 (69 worldwide citation)

1,2-Substituted biguanides of the formula ##EQU1## wherein R.sub.1 is saturated or unsaturated, straight-chain or branched hydrocarbon of 1-12 carbon atoms which is unsubstituted or substituted by one or more fluorine atoms; a cycloalkyl group of 3-6 carbon atoms; or an aryl or aralkyl group of the ...


4
Klemm Klaus: Surgical synthetic-resin material and method of treating osteomyelitis. Merck Patent Gesellschaft mit beschraenkter Haftung, Millen Raptes & White, May 13, 1975: US3882858 (66 worldwide citation)

Osteomyelitis is treated by filling an osteomyelitic cavity with particles of 1-20 mm diameter of a polymethacrylate, polyacrylate or copolymer thereof which is impregnated with gentamycin or other antibiotic. Particles of such antibiotic impregnated polymer joined together by a thread or wire are p ...


5
Vorbruggen Helmut, Niedballa Ulrich: Process for preparing cytidines. Schering Aktiengesellschaft, Millen Raptes & White, June 24, 1975: US3891623 (61 worldwide citation)

Cytidines of the formula ##SPC1##Wherein the R.sub.1 R.sub.2 N-- is a primary, secondary or tertiary amino group; R.sub.3 is hydrogen, halogen or lower alkyl of 1 to 6 carbon atoms; X is oxygen or sulfur; Y is nitrogen or CH; and Z is a free or blocked sugar residue having cytotoxic, anti-viral, enz ...


6
Imrich Sebestian, Istvan Halasz: Process for the chemical modification of surfaces of inorganic solids. Istvan Helsaz, Millen Raptes & White, May 11, 1976: US03956179 (58 worldwide citation)

A process for the chemical modification of the surfaces of inorganic solid bodies containing --OH groups, which comprises silanizing the free --OH groups with an alkylhalosilane to covalently bond the alkyl groups thereof to the oxygen atoms of the hydroxyl groups; halogenating or sulfochlorinating ...


7
Vorbruggen Helmut, Niedballa Ulrich: 5-azapyrimidine nucleosides. Schering Aktiengesellschaft, Millen Raptes & White, June 18, 1974: US3817980 (47 worldwide citation)

5-Azapyrimidine nucleosides of the formula ##SPC1##Wherein X is NH or an oxygen atom and Z is a free or blocked sugar residue having cytotoxic, antiviral, enzyme-inhibiting, immunosuppressive, anti-inflammatory and antipsoriatic activity are prepared by the reaction in the presence of a Lewis acid, ...


8
Lacroix Roger: Composite and porous metallic members which can be used for bone prosthesis. Comptoir Lyon Alemand Louyot, Millen Raptes & White, September 16, 1975: US3905777 (45 worldwide citation)

A prosthesis comprises a metal member of for example titanium or tantalum and includes a solid core or substrate and a covering of perforated metal of a porous nature. The perforations are preferably arranged in the foil so that when laminated the complete covering has pores of irregular shape. This ...


9
Reyhing Jorg, Rohde Wilhelm: Process and apparatus for the adsorptive purification of gases. Linde Aktiengesellschaft, Millen Raptes & White, May 7, 1974: US3808773 (43 worldwide citation)

A method for the adsorptive purification of gases containing water and one or more secondary components which comprises passing the gas through a molecular sieve bed, thereby charging the molecular sieve with adsorbable components, terminating charging of the molecular sieve upon the breakthrough of ...


10
Hans Dieter Orth, Wolfgang Brummer, Michael Klockow, Norbert Hennrich: Carrier matrix for the fixation of biochemically effective substances and process for the preparation thereof. Merck Patent Gesellschaft mit beschrankter Haftung, Millen Raptes & White, May 25, 1976: US03959080 (43 worldwide citation)

Biochemically active compounds e.g., proteins and particulate biological materials such as bacteria and viruses, are immobilized on a water-swellable or water-insoluble matrix by covalent bonding to a partially crosslinked polymer containing reactive groups capable of binding the biochemically activ ...