1
Joseph C Trautman, Lorin Olson: Self-actuating applicator for microprojection array. Alza Corporation, Michael J Atkins, August 29, 2006: US07097631 (205 worldwide citation)

An applicator for applying a microprojection member to the stratum corneum of a patient having a housing, a piston moveable within the housing and a cap adapted to activate the applicator. The applicator is self-setting and auto-triggering, which allows the applicator to be used by patient's having ...


2
Nancy Mills, Nouman A Muhammad, Jay Weiss, Russell U Nesbitt: Stable oral CI-981 formulation and process of preparing same. Warner Lambert Company, Michael J Atkins, November 11, 1997: US05686104 (118 worldwide citation)

An oral pharmaceutical composition is provided for treating hypercholestereolemia or hyperlipidemia containing an advantageous formulation for stabilizing the HMG-CoA coenzyme A inhibitor, CI-981 Hemi-Calcium, of formula (IA) ##STR1## with effective amounts of calcium carbonate. A method for prepari ...


3
S Shirley Yang, Wayne Boisvert, Nouman A Muhammad, Jay Weiss: Controlled release tacrine drug delivery systems and methods for preparing same. Warner Lambert Company, Michael J Atkins, November 19, 1996: US05576022 (47 worldwide citation)

The present invention pertains to controlled release tacrine drug delivery systems comprising an immediate release composition and a sustained release composition wherein (1) the immediate release composition comprises in percentages by weight of the immediate release composition: (A) immediate rele ...


4
Stanley Lech: Chewable soft gelatin-encapsulated pharmaceutical adsorbates. Warner Lambert Company, Michael J Atkins, Evan J Federman, February 22, 2000: US06027746 (46 worldwide citation)

The present invention relates to novel liquid oral suspensions incorporated within a soft gelatin capsule comprised of a bitter or bad-tasting pharmaceutical active (such as antihistamines, decongestants and the like) which is dispersed within an adsorbate comprised of magnesium trisilicate, silicon ...


5
Sadath U Khan, Phyllis Ying, Russell U Nesbitt, Mahdi B Fawzi, Jay Weiss: Dual control sustained release drug delivery systems and methods for preparing same. Warner Lambert Company, Michael J Atkins, August 12, 1997: US05656296 (36 worldwide citation)

The present invention pertains to a dual control sustained release drug delivery system which comprises a core and a porous coating layer over the core, wherein the coated core comprises (A) a core comprising in percentages by weight of the core composition (a) a medicament present in an amount from ...


6
Joseph C Trautman, Richard L Keenan, Ahmad P Samiee, WeiQi Lin, Michel J N Cormier, James A Matriano, Peter E Daddona: Apparatus and method for piercing skin with microprotrusions. Alza Corporation, Michael J Atkins, November 7, 2006: US07131960 (30 worldwide citation)

A method and device are described for applying a microprotrusion member (44) including a plurality of microprotrusions (90) to the stratum corneum with impact. The method and device are used to improve transport of an agent across the skin for agent delivery or sampling. The applicator (10, 60, 80) ...


7
W Michael Nichols, William Bess, Stanley Lech: Denaturants for sympathomimetic amine salts. Warner Lambert Company, Evan J Federman, Michael J Atkins, October 24, 2000: US06136864 (30 worldwide citation)

A pharmaceutical composition has an acid salt of a sympathomimetic amine; and a denaturant of (i) at least one gum or viscosity modifier, and (ii) at least one surfactant, wherein the gum or viscosity modifier and the surfactant are present in amounts sufficient to have a denaturing effect on the sy ...


8
Reynold Homan: PLA.sub.2 inhibitors and their use for inhibition of intestinal cholesterol absorption. Warner Lambert Company, Michael J Atkins, Charles W Ashbrook, April 2, 1996: US05504073 (26 worldwide citation)

Certain compounds have been synthesized and found to be effective inhibitors of phospholipase A.sub.2 (PLA.sub.2), and thereby useful in the treatment of intestinal cholesterol absorption and the disease states arising therefrom, such as hypercholesterolemia and coronary artery disease.


9
Wendy A Young, Michel J Cormier: Transdermal electrotransport delivery device including an antimicrobial compatible reservoir composition. Alza Corporation, Michael J Atkins, September 21, 2010: US07801599 (24 worldwide citation)

A transdermal electrotransport drug delivery device having an anode, a cathode and a source of electrical power electrically connected to the anode and the cathode. At least one of the anode and the cathode includes an electrode and a reservoir comprised of a housing composed of a polymeric material ...


10
Joseph Armand Picard, William Howard Roark, Bruce David Roth: Sulfonyl urea and carbamate ACAT inhibitors. Warner Lambert Company, Michael J Atkins, November 9, 1999: US05981595 (24 worldwide citation)

A pharmaceutically useful compound which lowers blood cholesterol levels having the formula ##STR1## wherein X is oxygen or --NH--; Ar is phenyl, substituted phenyl, naphthyl or substituted naphthyl; R.sub.1 is hydrogen, lower alkyl or benzyl; and R.sub.2 is a straight or branched alkyl group having ...