1
Schmutz Jean, Hunziker Fritz: Basically substituted heterocycles as anti-emetics. Wander Dr A, Sharkin Gerald D, Honor Robert S, McGovern Thomas O, September 23, 1975: US3908010 (20 worldwide citation)

Certain 11-basically substituted dibenzo?b,f!-?1,4!thiazepines and dibenzo?b,e! ?1,4!diazepines are useful as anti-emetics.


2
Simpson William R: Method for treating arrhythmia by using 1,4-bis(4 quinazolinyl) piperazines. Sandoz Wander, Sharkin Gerald D, Honor Robert S, McGovern Thomas O, May 20, 1975: US3885035 (19 worldwide citation)

Certain bis(4-quinazolinyl) piperazines, e.g., 1,4-bis(6,7-dimethoxy-4-quinazolinyl)piperazine, are useful as anti-arrhythmic agents.


3
Egger Helmut, Reinshagen Hellmuth: Substituted 14-desoxy-mutilins. Sandoz, Sharkin Gerald D, Hovor Robert S, McGovern Thomas O, November 11, 1975: US3919290 (18 worldwide citation)

This invention relates to new pleuromutilins of the formula: ##SPC1##WhereinEither R.sub.1 is ethyl or vinyl,N is an integer from 2 to 5,X is sulphur,And pharmaceutically acceptable acid addition salts and quaternary salts thereof.Processes for the preparation of such compounds are described.The com ...


4
Bastian Jean Michel, Hasspacher Klaus: Bis-P-hydroxy-phenethyl amines. Sandoz, Sharkin Gerald D, Honor Robert S, McGovern Thomas O, April 1, 1975: US3875233 (17 worldwide citation)

The invention concerns novel compounds of the formula: ##SPC1##Wherein R.sub.1 is hydroxyl, hydroxymethyl or--NH--SO.sub.2 --R.sub.3,wherein R.sub.3 is alkyl of 1 to 4 carbon atoms;R.sub.2 is hydroxymethyl when R.sub.1 is hydroxyl; or hydroxyl when R.sub.1 is other than hydroxyl; andA isI. when R.su ...


5
Rebane Arnold: Storable high protein chocolate snacks. Sandoz, Sharkin Gerald D, Honor Robert S, McGovern Thomas O, August 26, 1975: US3901977 (11 worldwide citation)

High protein chocolate snacks which retain their flavor and texture during storage are prepared by adding calcium caseinate, sodium caseinate and peanut butter to a uniform mixture of milk chocolate, dark chocolate and cocoa butter at a temperature between 80.degree. and 100.degree.F.


6
Bourquin Jean Pierre, Schwarb Gustav, Waldvogel Erwin: 4h-benzo[4,5]cyclohepta[1,2-6]thiophenes. Sandoz, Sharkin Gerald D, Honor Robert S, McGovern Thomas O, January 21, 1975: US3862156 (10 worldwide citation)

The present invention concerns new benzocycloheptathiophene derivatives possessing specific histaminolytic or antaminic properties.


7
Schmutz Jean, Hunziker Fritz, Kunzle Franz Martin: 11-Basically substituted dibenz [b,f] [1,4] oxazepines. Sandoz Wander, Sharkin Gerald D, Honor Robert S, McGovern Thomas O, May 20, 1975: US3884920 (10 worldwide citation)

Dibenz [b,f] [1,4] oxazepines, basically substituted at the 11-position and substituted at the 2-position with alkylsulphinyl or alkylsulphonyl are useful as neuroleptics and anti-emetics.


8
Neumann Peter: Certain 4-substituted amino-2,1,3-benzothiadiozoles. Sandoz Wander, Sharkin Gerald D, Honor Robert S, McGovern Thomas O, October 22, 1974: US3843668 (10 worldwide citation)

This invention concerns novel 2,1,3-benzothiadiazole derivatives of the formula: ##SPC1##Wherein each of R.sub.1, R.sub.2 and R.sub.3, independently, is hydrogen, halogen, alkyl, alkoxy, nitro, cyano, hydroxy or alkylthio,Useful as anti-tremor and anti-rigor agents.


9
Fehr Theodor, Hauth Hartmut: 13-Bromolysergic acid compounds. Sandoz, Sharkin Gerald D, Honor Robert S, McGovern Thomas O, August 26, 1975: US3901891 (9 worldwide citation)

The present invention concerns novel 13-bromolysergic acid compounds of formula I: ##SPC1##wherein R.sub.1 is methyl or isopropyl, andR.sub.2 is isopropyl, 1 or 2-methylpropyl or benzyl,Useful as agents for the treatment of cerebral insufficiency.


10
Schmutz Jean, Hunziker Fritz: Organic compounds in treatment of psychotic disturbances. Sandoz, Sharkin Gerald D, Honor Robert S, McGovern Thomas O, December 3, 1974: US3852446 (8 worldwide citation)

This invention concerns the use of the compound 2-nitro-11-(4-methyl-1-piperazinyl)dibenzo[b,f][1,4]-thiazepine, as a neuroleptic agent.