1
Youssef H Daher: Buttressing device usable in a vertebral prosthesis. Marshall O Toole Gerstein Murray & Bicknell, April 14, 1987: US04657550 (547 worldwide citation)

A device for maintaining the normal spacing between two vertebrae defining, in the vertebral column, the ends of a cavity resulting from the removal of at least a part of a vertebra comprises two bases each having means for anchorage in one of said end vertebrae; and adjustable buttressing means con ...


2
Radoje T Drmanac, Radomir B Crkvenjakov: Method of sequencing of genomes by hybridization of oligonucleotide probes. Marshall O Toole Gerstein Murray & Bicknell, April 13, 1993: US05202231 (438 worldwide citation)

The conditions under which oligonucleotides hybridize only with entirely homologous sequences are recognized. The sequence of a given DNA fragment is read by the hybridization and assembly of positively hybridizing probes through overlapping portions. By simultaneous hybridization of DNA molecules a ...


3
Bernard Ecanow: Drug delivery compositions and methods. Medaphore, Marshall O Toole Gerstein Murray & Bicknell, October 16, 1990: US04963367 (229 worldwide citation)

Drug delivery compositions yeild new and unexpected degrees of stabilization, solubilization and delivery of incorporated medicaments, drugs, or other physiologically-active compounds. The compositions enable administration of drugs and other medically useful compounds via a variety of routes. More ...


4
Angelo Yializis, David G Shaw, Donald S Strycker, Mooyoung Ham: High speed process for coating substrates. Spectrum Control, Marshall O Toole Gerstein Murray & Bicknell, June 27, 1989: US04842893 (188 worldwide citation)

A high-speed process for coating substrates with thin organic coatings in a vacuum is disclosed and claimed. The process utilizes relatively low boiling, reactive monomers (e.g., polyacrylates) which are flash vaporized, condensed on the substrates and cured, in situ. The resultant cured films are p ...


5
David G Shaw, Angelo Yializis, Donald S Strycker, Mooyoung Ham: Method of making a multi-layered article. Spectrum Control, Marshall O Toole Gerstein Murray & Bicknell, July 16, 1991: US05032461 (160 worldwide citation)

A high speed process for forming a multi layered thin film structure in a vacuum wherein each film is less than about four microns thick and the total layers can reach upwards to 4,000 or more. The polymeric layers are formed of a cross linked component selected from the group consisting of polyfunc ...


6
Wallace F Cook: Resuscitator bag. Intertech Resources, Marshall O Toole Gerstein Murray & Bicknell, October 4, 1988: US04774941 (159 worldwide citation)

A resuscitation apparatus for use during medical procedures is disclosed. The device comprises a squeeze bag having a gas inlet and a gas outlet, and a specifically configured valve joined to the bag over the gas outlet. The valve housing includes a squeeze bag port in flow communication with the ga ...


7
Hans Dietrich Polaschegg: Method and device for ultrafiltration during hemodialysis. Fresenius, Marshall O Toole Gerstein Murray & Bicknell, March 5, 1991: US04997570 (155 worldwide citation)

A method and a device for ultrafiltration during hemodialysis are described in which ultrafiltrate fluid, before removal from the dialysis circuit, is passed through a balancing device, which is also used as ultrafiltrate pump. For this purpose, a controller controls and actuates inlet, outlet, and ...


8
William V Fitzgerald: Diagnostic apparatus and method for fluid control valves. Fisher Controls International, Marshall O Toole Gerstein Murray & Bicknell, March 30, 1993: US05197328 (154 worldwide citation)

Apparatus and method for diagnostically testing and determining the operating condition of a pneumatically operated valve. A diagnostic controller is connected to a valve actuator assembly so that diaphragm pressure and valve plug movement among other inputs can be sensed while the valve actuator as ...


9
Yitzhak Stabinsky: Manufacture and expression of structural genes. Amgen, Marshall O Toole Gerstein Murray & Bicknell, March 24, 1987: US04652639 (138 worldwide citation)

Described are rapid and highly efficient procedures for the total synthesis of linear, double stranded DNA sequences of up to about 200 base pairs, which sequences may comprise entire structural genes. Illustratively disclosed is the preparation and expression of manufactured genes, including fusion ...


10
Yitzhak Stabinsky: Methods and kits for performing nucleic acid hybridization assays. Amgen, Marshall O Toole Gerstein Murray & Bicknell, June 14, 1988: US04751177 (137 worldwide citation)

A method for the isolation and quantitative detection of a selected single-stranded target polynucleotide from solution. The target polynucleotide is hybridized in solution to a single-stranded mediator polynucleotide, a probe polynucleotide, and an immobilized polynucleotide sequence. The sequence ...