1
Gary S David, Howard E Greene: Immunometric assays using monoclonal antibodies. Hybritech Incorporated, Lyon & Lyon, March 8, 1983: US04376110 (868 worldwide citation)

"Two-site" or "sandwich" immunometric assay techniques for determination of the presence and/or concentration of antigenic substances in fluids using monoclonal antibodies. One monoclonal antibody is presented in a soluble labeled form and a second monoclonal antibody is presented bound to a solid c ...


2
Robert J Crowley, John E Abele, Charles D Lennox, Susan M Ropiak: Catheters for imaging, sensing electrical potentials, and ablating tissue. Boston Scientific Corporation, Lyon & Lyon, December 21, 1999: US06004269 (860 worldwide citation)

An acoustic imaging system for use within a heart has a catheter (6), an ultrasound device (10) incorporated into the catheter (6), and an electrode (300, 304, 334, 394) mounted on the catheter (6). The ultrasound device (10) directs ultrasonic signals toward an internal structure in the heart to cr ...


3
Ronald A Katz, Gary L West, Thomas B Barker: Methods and apparatus for intelligent selection of goods and services in telephonic and electronic commerce. Telebuyer, Lyon & Lyon, April 25, 2000: US06055513 (652 worldwide citation)

Apparatus and methods are provided for effecting remote commerce, such as in telemarketing (either inbound or outbound) and in electronic commerce, which are particularly adapted for the intelligent selection and proffer of products, services or information to a user or customer. In one aspect of th ...


4
Michael J Heller, Eugene Tu: Active programmable electronic devices for molecular biological analysis and diagnostics. Nanogen, Lyon & Lyon, February 25, 1997: US05605662 (631 worldwide citation)

A self-addressable, self-assembling microelectronic device is designed and fabricated to actively carry out and control multi-step and multiplex molecular biological reactions in microscopic formats. These reactions include nucleic acid hybridization, antibody/antigen reaction, diagnostics, and biop ...


5
John E Abele: Heart ablation catheter with expandable electrode and method of coupling energy to an electrode on a catheter shaft. Boston Scientific Corporation, Lyon & Lyon, January 19, 1999: US05860974 (627 worldwide citation)

An expandable ablation electrode is provided on a catheter constructed to access the heart. When the electrode is introduced to the heart, it is small and suitably flexible to maneuver through the torturous path. However, when the catheter is in place in the heart, the electrode is expansible in dia ...


6
Denise Barbut, Jonathan D Root, Robert Rizzari, James M Sellers, Giovanni Pastrone, John McKenzie: Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries. Embol X, Lyon & Lyon, September 2, 1997: US05662671 (595 worldwide citation)

An arterial catheter system for removing plaque from the aorta and other arteries is disclosed. The system typically includes an elongate catheter member, a filtration apparatus disposed within the distal region, and an atherectomy assembly which includes a mechanism for trapping and holding mobile ...


7
Yik S Kwoh: Imaging device - aided robotic stereotaxis system. Lyon & Lyon, January 7, 1992: US05078140 (584 worldwide citation)

An apparatus and method for computer controlled stereotactic surgery is disclosed. This method utilizes an imaging device, a robotic arm and a means for controlling the robotic arm. Stereotactic surgery on integral body parts, e.g. the brain, spine, knee or other joint, breast, etc. may be accomplis ...


8
Kevin O Neil, Glenn R Seidman: Personal information security and exchange tool. Cyva Research Corporation, Lyon & Lyon, November 16, 1999: US05987440 (545 worldwide citation)

Utilization of the E-Metro Community and Personal Information Agents assure an effective and comprehensive agent-rule based command and control of informational assets in a networked computer environment. The concerns of informational privacy and informational self-determination are addressed square ...


9
Ross S Tsugita, Tracy D Maahs, Yue Teh Jang: Percutaneous catheter and guidewire having filter and medical device deployment capabilities. Embol X, Lyon & Lyon, June 15, 1999: US05911734 (511 worldwide citation)

An apparatus and method for treating stenosed blood vessels is provided, more particularly a percutaneous catheter, including a filter for capturing loose embolic material, used to deliver a stent, preferably within the ascending aorta, the aortic arch, or the carotid arteries. The catheter includes ...


10
Michael J Heller, Eugene Tu, William F Butler: Molecular biological diagnostic systems including electrodes. Nanogen, Lyon & Lyon, May 27, 1997: US05632957 (507 worldwide citation)

A system for performing molecular biological diagnosis, analysis and multi-step and multiplex reactions utilizes a self-addressable, self-assembling microelectronic system for actively carrying out controlled reactions in microscopic formats. These reactions include most molecular biological procedu ...



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