1
Ken Tseung, Wai Bun Wong, Glenn K Takayama, Christopher M Jones, Krishan L Kalra: Automated staining apparatus. BioGenex Laboratories, Richard Neeley, Luann Cserr, August 8, 1995: US05439649 (219 worldwide citation)

An automated microscope-slide-staining apparatus, having a supporting framework; an arm moveable in three dimensions attached to the framework; apparatus for moving the arm; a hollow tip head located on the arm; apparatus for alternatively supplying positive or negative gas pressure to the hollow ti ...


2
Gray Shaw, Geertruida Veldman, Joseph L Wooters: Cysteine added variants of interleukin-3 and chemical modifications thereof. Genetics Institute, Luann Cserr, Bruce Eisen, November 24, 1992: US05166322 (172 worldwide citation)

Cysteine added variants ("CAVs") of interleukin-3 are provided having one or more cysteine residues substituted for selected naturally occurring amino acid residues, or inserted into the polypeptide sequence, and preferably being further modified by deletion of certain N-terminal amino acids. Such C ...


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John McCoy, Edward R LaVallie: Peptide and protein fusions to thioredoxin and thioredoxin-like molecules. Genetics Institute, Luann Cserr, Maureen C Meinert, Bruce M Eisen, December 14, 1993: US05270181 (70 worldwide citation)

This invention provides a fusion molecule comprising a DNA sequence encoding a thioredoxin-like protein fused to the DNA sequence encoding a selected heterologous peptide or protein. The peptide or protein may be fused to the amino terminus of the thioredoxin-like molecule, the carboxyl terminus of ...


5
Neil T Parkin, Kathleen L Coelingh: Temperature sensitive clustered changed-to-alanine mutants of influenza virus PB2 gene. Aviron, Luann Cserr, Tracy Dunn, November 25, 1997: US05690937 (56 worldwide citation)

Recombinant PB2 variant influenza viruses, RNA, cDNA and vectors are provided. Also provided are immunogenic compositions containing the variant viruses, methods of producing such viruses and methods for the prophylactic treatment of influenza in humans.


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Neil T Parkin: Recombinant tryptophan mutants of influenza. Aviron, Luann Cserr, Tracy Dunn, November 27, 2001: US06322967 (54 worldwide citation)

Recombinant PB2 tryptophan variant influenza viruses, RNA, cDNA and vectors are provided. Also provided are immunogenic compositions containing the variant viruses, methods of producing such viruses and methods for the prophylactic treatment of influenza in humans.


7
Randal J Kaufman, Debra Pittman: Production of procoagulant proteins. Genetics Institute, Bruce M Eisen, Luann Cserr, David Berstein, April 2, 1991: US05004803 (34 worldwide citation)

Hybrid procoagulant proteins are disclosed which contain peptide sequences of human blood coagulation factors V and VIII. DNA molecules encoding these proteins and materials and methods for expressing them are also disclosed. Preferably, peptide sequence in the B domain of Factor VIII is replaced wi ...


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Neil T Parkin: Recombinant tryptophan mutants of influenza. Aviron, Luann Cserr, Tracy Dunn, July 18, 2000: US06090391 (33 worldwide citation)

Recombinant PB2 tryptophan variant influenza viruses, RNA, cDNA and vectors are provided. Also provided are immunogenic compositions containing the variant viruses, methods of producing such viruses and methods for the prophylactic treatment of influenza in humans.


9
Nick W Warne, Camille L Bedrosian, James C Keith Jr, Ullrich S Schwertschlag, Paul F Schendel: Methods of treating inflammatory bowel diseases by administering IL-11. Genetics Institute, Luann Cserr, Barbara Gyure, October 3, 2000: US06126933 (26 worldwide citation)

Provided by the present invention are topical formulations of Interleukin-11 and methods for treating a variety of disorders, including inflammatory bowel diseases (e.g., Crohn's disease, ulcerative colitis, indeterminate colitis, and infectious colitis), mucositis (e.g., oral mucositis, gastrointes ...


10
Daniel Robert Henderson: Methods for protein binding enzyme complementation assays. Microgenics Corporation, Luann Cserr, July 1, 1997: US05643734 (25 worldwide citation)

This invention relates to improved methods and novel compositions for enzyme complementation assays for qualitative and quantitative determination of a suspected analyte in a sample. The use of enzyme-acceptor and enzyme-donor polypeptides prepared by recombinant DNA techniques, DNA synthesis or che ...