51
Claus Riemer: Benzyl-piperidine derivatives. Hoffmann La Roche, George W Johnston, William H Epstein, Lewis J Kreisler, May 19, 1998: US05753679 (2 worldwide citation)

Benzly-piperidine derivatives of formula I and their pharmaceutically acceptable salts are used in the control of psychotic disorders which are caused by damage to the dopamine system, especially schizophrenia. ##STR1## A is ##STR2## B is ##STR3## R.sup.1, R.sup.2 and R.sup.3 are independently hydro ...


52
Kirvin L Hodge, Shalini Sharma, Reid W von Borstel, Stephen D Wolpe: Compounds for the treatment of metabolic disorders. Wellstat Therapeutics Corporation, Lewis J Kreisler, July 5, 2011: US07973052 (1 worldwide citation)

Agents useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis are disclosed. wherein n is 1 or 2; m is 0, 1, 2, 3 or 4; q is 0 or 1; t is 0 or 1; R2 is alkyl ...


53
Kirvin L Hodge, Shalini Sharma, Reid W von Borstel: Compositions for the treatment of metabolic disorders. Wellstat Therapeutics Corporation, Lewis J Kreisler, July 6, 2010: US07749990 (1 worldwide citation)

Agents useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis are disclosed. wherein n is 1 or 2; m is 0 to 4; q is 0 or 1; t is 0 or 1; R2 is alkyl having fr ...


54
Shalini Sharma, Reid W von Borstel: Compounds for the treatment of metabolic disorders. Wellstat Therapeutics Corporation, Lewis J Kreisler, September 20, 2011: US08022249 (1 worldwide citation)

Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis are disclosed. wherein n is 1 or 2; m is 0, 1, 2, 3, 4 or 5; q is 0 or 1; t is 0 or 1; R1 is ...


55
James Dennen O Neil, Michael K Bamat, Reid W von Borstel, Shalini Sharma, Ramachandran Arudchandran: Compounds and method for reducing uric acid. Wellstat Therapeutics Corporation, Lewis J Kreisler, September 9, 2014: US08829058 (1 worldwide citation)

Uric acid in mammalian subjects is reduced and excretion of uric acid is increased by administering a compound of Formula I or a pharmaceutically acceptable salt thereof. In Formula I m is 0, 1, 2, 3 or 4; n is 0 or 1; t is 0 or 1; q is 0 or 1; and r is 0, 1 or 2. R6 is hydrogen, O or hydroxyl. R7 i ...


56
Shalini Sharma, Reid W von Borstel: Compounds for the treatment of metabolic disorders. Wellstat Therapeutics Corporation, Lewis J Kreisler, May 3, 2011: US07935689 (1 worldwide citation)

Agents useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, polycystic ovary syndrome, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis are disclosed, compound of the formula (I): wherein n is 1 or 2; m is ...


57
Shalini Sharma, Reid W von Borstel: Compounds for the treatment of metabolic disorders. Wellstat Therapeutics Corporation, Lewis J Kreisler, May 24, 2011: US07947735 (1 worldwide citation)

Agents useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, polycystic ovary syndrome, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis are disclosed. Formula (I), wherein n is 1 or 2; m is 0, 1, 2, 3, or ...


58
Shalini Sharma, Reid W von Borstel: Compounds for the treatment of metabolic disorders. Wellstat Therapeutics Corporation, Lewis J Kreisler, October 26, 2010: US07820721 (1 worldwide citation)

Agents useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, polycystic ovary syndrome, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis are disclosed. wherein n is 1 or 2; m is 0, 1, 2, 3, or 4; q is 0 or ...


59
James Dennen O Neil, Shalini Sharma, Ramachandran Arudchandran: Tetrazole compounds for reducing uric acid. Wellstat Therapeutics Corporation, Lewis J Kreisler, April 2, 2013: US08410154 (1 worldwide citation)

Uric acid in mammalian subjects is reduced and excretion of uric acid is increased by administering a compound of Formula I. The uric acid-lowering effects of the compounds of this invention are used to treat or prevent a variety of conditions including gout, hyperuricemia, elevated levels of uric a ...


60
Shalini Sharma: Compounds for the treatment of metabolic disorders. Wellstat Therapeutics Corporation, Lewis J Kreisler, March 15, 2011: US07906675 (1 worldwide citation)

A biologically active agent, wherein the agent is a compound of the formula: Wherein A, R5, R9, X, Q and n, m, q are defined herein below.