1
John Hakimi, Patricia Kilian, Perry Rosen: Polyethylene-protein conjugates. Hoffmann La Roche, George W Johnston, William H Epstein, Lewis J Kreisler, May 5, 1998: US05747646 (127 worldwide citation)

The present invention is a physiologically active, substantially non-immunogenic water soluble polyethylene glycol protein conjugate having the same utility as the protein which forms the conjugate, without having the same properties of producing an immunogenic response possessed by the protein whic ...


2
John Hakimi, Patricia Kilian, Perry Rosen: Polyethylene-protein conjugates. Hoffman La Roche, George W Johnston, William H Epstein, Lewis J Kreisler, November 10, 1998: US05834594 (120 worldwide citation)

The present invention is a physiologically active, substantially non-immunogenic water soluble polyethylene glycol protein conjugate having the same utility as the protein which forms the conjugate, without having the same properties of producing an immunogenic response possessed by the protein whic ...


3
John Hakimi, Patricia Kilian, Perry Rosen: Polyethylene-protein conjugates. Hoffmann La Roche, George W Johnston, William H Epstein, Lewis J Kreisler, August 11, 1998: US05792834 (69 worldwide citation)

The present invention is a physiologically active, substantially non-immunogenic water soluble polyethylene glycol protein conjugate having the same utility as the protein which forms the conjugate, without having the same properties of producing an immunogenic response possessed by the protein whic ...


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Shalini Sharma, Reid W von Borstel: Compounds for the treatment of metabolic disorders. Wellstat Therapeutics Corporation, Lewis J Kreisler, August 2, 2005: US06924314 (40 worldwide citation)

Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.


7
Arthur Campfield, Rene Devos, Yves Guisez: Pegylated obese (ob) protein compositions. Hoffman La Roche, George W Johnston, William H Epstein, Lewis J Kreisler, February 15, 2000: US06025325 (40 worldwide citation)

Polyethylene and polypropylene protein conjugates which modulate body weight of animals and humans for the treatment, prevention and control of obesity and associated diseases or conditions, and the recombinant expression of these biologically active proteins in purified and homogeneous forms.


8
Shalini Sharma, Reid W von Borstel: Compounds for the treatment of metabolic disorders. Wellstat Therapeutics Corporation, Lewis J Kreisler, March 14, 2006: US07012071 (31 worldwide citation)

Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.


9
Shalini Sharma, Reid W von Borstel: Compounds for the treatment of metabolic disorders. Wellstat Therapeutics Corporation, Lewis J Kreisler, September 5, 2006: US07101910 (30 worldwide citation)

Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.


10
Shalini Sharma: Compounds for the treatment of metabolic disorders. Wellstat Therapeutics Corporation, Lewis J Kreisler, May 9, 2006: US07041659 (30 worldwide citation)

Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.