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Davis Ward Ronda, Mook Robert Anthony Jr, Neeb Michael J, Salovich James M: Pyrimidine compounds. Smithkline Beecham Corporation, Davis Ward Ronda, Mook Robert Anthony Jr, Neeb Michael J, Salovich James M, LEVY David J, September 2, 2004: WO/2004/074244 (95 worldwide citation)

The present invention provides compounds of formula (I) : wherein all variables are as defined herein, pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.


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Alberti Michael John, Drewry David Harold, Miller David Drysdale, Bamborough Paul: Chemical compounds. Smithkline Beecham Corporation, Alberti Michael John, Drewry David Harold, Miller David Drysdale, Bamborough Paul, LEVY David J, October 7, 2004: WO/2004/084813 (19 worldwide citation)

The present invention relates to aminopyrazine derivatives, compositions and medicaments containing the same, as well as processes for the preparation and use of such compounds, compositions and medicaments. Such aminopyrazine derivatives are useful in the treatment of diseases associated with inapp ...


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Britton Jonathan E, Fang Jing, Heyer Dennis, Miller Aaron Bayne, Navas Frank Iii, Smalley Terrence Lee Jr, Zuercher William J, Katamreddy Subba Reddy: Cycloalkylidene compounds as modulators of estrogen receptor. Smithkline Beecham Corporation, Britton Jonathan E, Fang Jing, Heyer Dennis, Miller Aaron Bayne, Navas Frank Iii, Smalley Terrence Lee Jr, Zuercher William J, Katamreddy Subba Reddy, LEVY David J, February 10, 2005: WO/2005/012220 (18 worldwide citation)

The present invention relates to novel compounds with a variety of therapeutic uses, more particularly novel substituted cyclic alkylidene compounds that are particularly useful for selective estrogen receptor modulation. Formula (I) including salts, solvates, and pharmacologically functional deriva ...


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Duan Maosheng, Kazmierski Wieslaw Mieczyslaw, Aquino Christopher Joseph: Cyclohexyl compounds as ccr5 antagonists. Smithkline Beecham Corporation, Duan Maosheng, Kazmierski Wieslaw Mieczyslaw, Aquino Christopher Joseph, LEVY David J, July 1, 2004: WO/2004/054581 (18 worldwide citation)

The present invention relates to compounds of formula (I), or pharmaceutically acceptable derivatives thereof, useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatme ...


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