1
James T Holen, Enrique Hicaro Jr, Caryn G Putterman, Tung Ming Huang, Carl W Merkh: Reaction cartridge and carousel for biological sample analyzer. Abbott Laboratories, Lawrence S Pope, June 14, 1994: US05320808 (275 worldwide citation)

A semi-automated biological sample analyzer and subsystems are provided to simultaneously perform a plurality of enzyme immuno assays for human IgE class antibodies specific to a panel of preselected allergens in each of a plurality of biological samples. A carousel is provided to position and hold ...


2
Larry G Birkenmeyer, John J Carrino, Bruce J Dille, Hsiang Yun Hu, Jon D Kratochvil, Thomas G Laffler, Ronald L Marshall, Laurie A Rinehardt, Natalie A Solomon: Amplification of target nucleic acids using gap filling ligase chain reaction. Abbott Laboratories, Thomas D Brainard, Lawrence S Pope, June 27, 1995: US05427930 (232 worldwide citation)

An improved, "gap filling" embodiment of the Ligase Chain Reaction (LCR) is described. Gap filling LCR is LCR wherein at least one of the probes is recessed so that a gap is formed between the adjacent probes when they are hybridized to target. The gap is filled using polymerase and deoxyribonucleot ...


3
Peter J Tarcha, James J Donovan, Martin Wong: Indicator reagents, diagnostic assays and test kits employing organic polymer latex particles. Abbott Laboratories, Gregory W Steele, Thomas M Breininger, Lawrence S Pope, October 12, 1993: US05252459 (135 worldwide citation)

An indicator reagent, assay method and test kit for determining the presence or amount of an analyte in a test sample, in which the indicator reagent is formed by attaching an organic polymer latex particle, preferably a colored particle, to a specific binding member. The specific binding member can ...


4
Helmut Reiff, Wolfgang Wenzel, Jurgen Grammel, Dieter Dieterich: Aqueous polyurethane dispersions from solvent-free prepolymers using sulfonate diols. Bayer Aktiengesellschaft, Gene Harsh, Lawrence S Pope, Frederick H Colen, August 22, 1978: US04108814 (132 worldwide citation)

This invention relates to a process for the production of water dispersible polyurethanes by reacting polyisocyanates with sulphonate group containing diols. The sulphonate diols have the general formula: ##STR1## WHEREIN A and B, which may be the same or different, each represents a divalent alipha ...


5
Wulf von Bonin, Ulrich von Gizycki, Kuno Wagner, Dietmar Schapel: Constructional material. Bayer Aktiengesellschaft, Gene Harsh, Lawrence S Pope, October 25, 1983: US04411262 (114 worldwide citation)

The present invention relates to a constructional material which is stable in storage and which is kept under moisture-free conditions and which comprises a substrate and a reactive one-component system which hardens on exposure to air by reaction with moisture. The present invention also relates to ...


6
William E Brown III, Sarah E Safford, John M Clemens: Solid-phase analytical device and method for using same. Abbott Laboratories, Thomas D Brainard, Lawrence S Pope, November 3, 1992: US05160701 (108 worldwide citation)

A novel material and device useful in solid-phase binding assays to determine the presence or amount of an analyte in a test sample, particularly antigens, antibodies, or other ligands or DNA segments. The material and device comprises a reaction site having procedural controls and an analyte bindin ...


7
Yi Her Jou, Stephen D Stroupe, James J Markese: Devices for performing ion-capture binding assays. Abbott Laboratories, Lawrence S Pope, September 23, 1997: US05670381 (106 worldwide citation)

This invention presents novel assay devices employing capture reagents, involving a specific binding member attached to a charged substance, and porous material containing a capture or reaction zone that is oppositely charged with respect to the charged substance included in the capture reagent. In ...


8
Karsten Josef Idel, Dieter Frietag, Werner Nouvertne: Branched, high-molecular weight thermoplastic polycarbonates. Bayer Aktiengesellschaft, Gene Harsh, Lawrence S Pope, January 22, 1980: US04185009 (106 worldwide citation)

The invention relates to a process for the preparation of branched, thermoplastic, high-molecular weight and soluble polycarbonates having improved properties, by incorporation of 3,3-bis-(4-hydroxyaryl)-oxindoles as a branching agent. The invention further relates to the polycarbonates obtained in ...


9
Siegfried Adelmann, Dieter Margotte, Hugo Vernaleken, Werner Nouvertne: Thermoplastic polycarbonate molding materials with improved mold release. Bayer Aktiengesellschaft, Gene Harsh, Lawrence S Pope, December 26, 1978: US04131575 (100 worldwide citation)

The present invention is concerned with thermoplastic molding materials of high molecular weight, thermoplastic, aromatic polycarbonates based on aromatic dihydroxy compounds and containing from about 0.01 to 0.1% by weight of esters of saturated aliphatic carboxylic acids with 10 to 20 C atoms and ...


10
Peter Markusch: Stable, colloidal, aqueous dispersions of cross-linked urea-urethane polymers and their method of production. Mobay Chemical Corporation, Gene Harsh, Lawrence S Pope, Thomas W Roy, October 4, 1983: US04408008 (98 worldwide citation)

The present invention relates to a process for the preparation of stable, colloidal, aqueous dispersions of cross-linked urea-urethanes which comprises reacting