1
Iyengar Sridhar G, Harding Ian: Method and apparatus for assay of electrochemical properties. Agamatrix, Iyengar Sridhar G, Harding Ian, LARSON Marina T, March 10, 2005: WO/2005/022143 (126 worldwide citation)

The presence of a select analyte in the sample is evaluated in an electrochemical system using a conduction cell-type apparatus. A potential or current is generated between the two electrodes of the cell sufficient to bring about oxidation or reduction of the analyte or of a mediator in an analyte-d ...


2
Flaherty Joseph, Harding Ian, Huang Eileen, Iyengar Sridhar G, Vu Sonny, Wei Baoguo, Diamond Steven, Forest Martin: Measuring device and methods for use therewith. Agamatrix, Flaherty Joseph, Harding Ian, Huang Eileen, Iyengar Sridhar G, Vu Sonny, Wei Baoguo, Diamond Steven, Forest Martin, LARSON Marina T, December 15, 2005: WO/2005/119234 (111 worldwide citation)

The ability to switch at will between amperometric measurements and potentiometric measurements provides great flexibility in performing analyses of unknowns. Apparatus and methods can provide such switching to collect data from an electrochemical cell. The cell may contain a reagent disposed to mea ...


3
Harding Ian: Connector configuration for electrochemical cells and meters for use in combination therewith. Agamatrix, Harding Ian, LARSON Marina T PhD, December 8, 2005: WO/2005/116622 (107 worldwide citation)

A substantially planar electrochemical test strip for determination of the presence and/or quantity of an analyte in a sample is provided that has a first electrode, a first connector including two contact pads, and a first conductive lead extending between the first electrode and the first connecto ...


4
Waterhouse Paul, Stevens John: Radio tag and system. Visible Assets, Waterhouse Paul, Stevens John, LARSON Marina T, April 12, 2007: WO/2007/039835 (15 worldwide citation)

Passive tags use two antennas with only limited mutual coupling, one of which receives a power/clock field and the other of which receives a data signal. An area-reading antenna, or two or more antennas, are deployed to generate the power/clock field, from a base station. The base station, or active ...


5
Harding Ian, Williams Richard, Iyengar Sridhar: Analyte determination method and analyte meter. Agamatrix, Harding Ian, Williams Richard, Iyengar Sridhar, LARSON Marina T, October 19, 2006: WO/2006/109279 (13 worldwide citation)

The presence of oxygen or red blood cells in a sample applied to an electrochemical test strip that makes use of a reduced mediator is corrected for by an additive correction factor that is determined as a function of the temperature of the sample and a measurement that reflects the oxygen carrying ...


6
Chiosis Gabriela, Huazhong He, Llauger Bufi Laura, Kim Joungnam, Larson Steve M, Smith Jones Peter: Small-molecule hsp90 inhibitors. Sloan Kettering Institute For Cancer Research, Chiosis Gabriela, Huazhong He, Llauger Bufi Laura, Kim Joungnam, Larson Steve M, Smith Jones Peter, LARSON Marina T, August 10, 2006: WO/2006/084030 (11 worldwide citation)

Hsp90 inhibitors havin are rovided havin the formula: (I) with a 2',4',5'-substitution pattern on the right-side aryl moiety. X1 represents two substituents, which may be the same or different, disposed in the 4' and 5' positions on the aryl group, wherein X1 is selected from halogen, alkyl, alkoxy, ...


7
Miesenbock Gero A, Zemelman Boris V: Heterologous stimulus-gated ion channels and methods of using same. Sloan Kettering Institute For Cancer Research, Miesenbock Gero A, Zemelman Boris V, LARSON Marina T, December 11, 2003: WO/2003/102156 (10 worldwide citation)

Methods and compositions to activate a genetically designated target cell (or population of targetcells) artificially, in vivo or in vitro, employ triggering of heterologous stimulus-gated ion channels to activate the cells. The stimulus-gated ion channels are suitably TRPV1, TRPM8 or P2X2. A stimul ...


8
Goldberg Edward H, Guertin Robert P, Harrah Timothy P: Magnetic protein nanosensors and methods of use. Tufts University, Goldberg Edward H, Guertin Robert P, Harrah Timothy P, LARSON Marina T, October 5, 2006: WO/2006/104700 (9 worldwide citation)

Nanometer-scale sensors useful in the detection of biological and chemical entities are formed from a protein rod body portion (41), a magnetic particle (42) affixed to the protein rod body portion (41); and an analyte binding moiety (43) disposed on the protein rod body portion (41) at a location r ...


9
Chiosis Gabriela, Greengard Paul, Dou Fei, Luo Wenjie: Treatment of neurodegenerative diseases through inhibiton of hsp90. Sloan Kettering Institute For Cancer Research, The Rockefeller University, Chiosis Gabriela, Greengard Paul, Dou Fei, Luo Wenjie, LARSON Marina T, January 10, 2008: WO/2008/005937 (9 worldwide citation)

Treatment of neurodegenerativ e diseases is achiev ed using smal l molecule purine scaffold compounds that inhibit Hsp90 and that possess the ability to cross the blood-biain bairiei or are othei wise delivered to the brain.


10
Harding Ian, Williams Richard: Method and apparatus for detection of abnormal traces during electrochemical analyte detection. Agamatrix, Harding Ian, Williams Richard, LARSON Marina T, October 19, 2006: WO/2006/109280 (7 worldwide citation)

Detection of abnormal signal traces in electrochemical measurements generated using an electrochemical test strip to which a potential is applied allows for an indication of an erroneous analyte determination. The current trace has an expected shape in which a peak current is observed a time tpeak a ...