1
Kevin R Stone, Allen H DeSatnick: Suture anchor assembly. Kevin R Stone, Lappin & Kusmer, December 6, 1994: US05370662 (427 worldwide citation)

Suture anchor assembly for attaching soft tissue to bone. The assembly includes an elongated member having a self-tapping threaded portion at one proximal end, and an integral eyelet for receiving a suture at its distal end. The distal end further includes a receiver for a rotating driver device, su ...


2
Kevin R Stone, Shu Tung Li: Prosthetic articular cartilage. ReGen Corporation, Lappin & Kusmer, April 26, 1994: US05306311 (405 worldwide citation)

A prosthetic, resorbable articular cartilage and methods of its fabrication and insertion are disclosed. The prosthetic articular cartilage, when implanted in a humanoid joint, acts as a resorbable scaffold for ingrowth of native articular chondrocytes and supports natural articulating joint forces. ...


3
Mark A Saab: Heat transfer catheters and methods of making and using same. Lappin & Kusmer, April 29, 1997: US05624392 (357 worldwide citation)

Heat transfer catheter apparatus and methods of making and using same are disclosed wherein fluid connection means is provided between the distal portions of two adjacent, thin-walled, high strength fluid lumens to define a closed loop fluid circulation system capable of controlled delivery of therm ...


4
Michael A Martinelli: Method and system for navigating a catheter probe. Lappin & Kusmer, January 14, 1997: US05592939 (300 worldwide citation)

A system for navigating a catheter probe through a body cavity includes a sensing coil affixed to a distal end of the probe. Magnetic fields are projected into the body cavity to induce voltage signals in the sensing coil that are sufficient to describe the orientation and position of the probe. A s ...


5
Mark A Saab: Multi-lumen balloons and catheters made therewith. Advanced Polymers Incorporated, Lappin & Kusmer, August 30, 1994: US05342301 (255 worldwide citation)

Multi-lumen balloons for use as or in conjunction with balloon dilation catheters, and methods for making such balloons, are disclosed.


6
Kevin R Stone, Allen H DeSatnick: Suture anchor assembly. Kevin R Stone, Lappin & Kusmer, August 22, 1995: US05443482 (225 worldwide citation)

Suture anchor assembly for attaching soft tissue to bone. The assembly includes an elongated member having a self-tapping threaded portion at one proximal end, and an integral eyelet for receiving a suture at its distal end. The distal end further includes a receiver for a rotating driver device, su ...


7
Sudhir Agrawal, Jin Yan Tang: Aminoalkylphosphorothioamidate oligonucleotide deratives. Worcester Foundation for Biomedical Research, Lappin & Kusmer, July 16, 1996: US05536821 (218 worldwide citation)

Disclosed are methods of producing a synthetic oligonucleotide of selected nucleotide sequence which is internally functionalized at at least one selected location with an aminoalkylphosphorothioamidate and labelled with a nonradioactive material. Also disclosed are oligonucleotides produced by this ...


8
Sudhir Agrawal, Jin Yan Tang: Aminoalkylphosphotriester oligonucleotide derivatives. Worcester Foundation for Biomedical Research, Lappin & Kusmer, July 30, 1996: US05541306 (216 worldwide citation)

Disclosed are methods of producing a synthetic oligonucleotide of selected nucleotide sequence which is internally functionalized at least one selected location with an aminoalkylphosphotriester, and labelled with a nonradioactive material. Also disclosed are oligonucleotides produced by this method ...


9
Sudhir Agrawal, Jinyan Tang: Site-specific functionalization of oligodeoxynucleotides for non-radioactive labelling. Hybridon, Lappin & Kusmer, June 14, 1994: US05321131 (210 worldwide citation)

Disclosed are compounds consisting of a plurality of nucleosides which are covalently linked by at least one aminoalkylphosphoramidate linkage of the formula ##STR1## wherein n=2 to 6 and Nu.sub.1 and Nu.sub.2 represent nucleoside phosphates.


10
Sudhir Agrawal, Jin Yan Tang: Linear aminoalkylphosphoramidate oligonucleotide derivatives. Worcester Foundation for Biomedical Research, Lappin & Kusmer, October 8, 1996: US05563253 (206 worldwide citation)

Disclosed are methods of producing a synthetic oligonucleotide of selected nucleotide sequence which is internally functionalized at at least one selected location with an aminoalkyl-phosphoramidate and labelled with a nonradioactive material. Also disclosed are oligonucleotides produced by this met ...



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