Marvin J Slepian: Method and apparatus for treatment of focal disease in hollow tubular organs and other tissue lumens. Endoluminal Therapeutics, Kilpatrick & Cody, July 12, 1994: US05328471 (541 worldwide citation)

Diseased portions of tissue lumens can be advantageously treated by the focal introduction of at least one therapeutic agent to the lumen at the diseased point. This can be accomplished by

Jeffrey A Hubbell, Chandrashekhar P Pathak, Amarpreet S Sawhney, Neil P Desai, Jennifer L Hill: Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers. Board of Regents The University of Texas System, Kilpatrick & Cody, April 25, 1995: US05410016 (484 worldwide citation)

Hydrogels of polymerized and crosslinked macromers comprising hydrophilic oligomers having biodegradable monomeric or oligomeric extensions, which biodegradable extensions are terminated on free ends with end cap monomers or oligomers capable of polymerization and cross linking are described. The hy ...

David S Soane, Zoya M Soane: Method and device for moving molecules by the application of a plurality of electrical fields. Soane Tecnologies, Kilpatrick & Cody, June 30, 1992: US05126022 (438 worldwide citation)

Devices and methods are disclosed for moving charged molecules through a medium by the application of a plurality of electrical fields of sufficient strength and applied for sufficient amounts of time so as to move the charged molecules through the medium. The devices although preferably small in si ...

Joseph P Vacanti, Charles A Vacanti, Robert S Langer: Neomorphogenesis of cartilage in vivo from cell culture. Massachusetts Institute of Technology, Children s Hospital, Kilpatrick & Cody, August 20, 1991: US05041138 (401 worldwide citation)

Methods and artificial matrices for the growth and implantation of cartilaginous structures and surfaces are disclosed. In the preferred embodiments, chondrocytes are grown on biodegradable, biocompatible fibrous polymeric matrices. Optionally, the cells are proliferated in vitro until an adequate c ...

L Scott Humphries, Glenn Rasmussen, Douglas L Voita, James D Pritchett: Home automation system. IntelliNet, George T Marcou, Kilpatrick & Cody L, April 15, 1997: US05621662 (364 worldwide citation)

A home automation system comprises a number of sub-systems for controlling various aspects of a house, such as a security sub-system, an HVAC sub-system, a lighting control sub-system, and an entertainment sub-system. The network comprises a host computer connected through a host interface to a plur ...

Solomon Steiner, Robert Rosen: Delivery systems for pharmacological agents encapsulated with proteinoids. Clinical Technologies Associates, Kilpatrick & Cody, May 15, 1990: US04925673 (363 worldwide citation)

Methods are described for targeting the release of an active pharmacological agent in an animal by administering that agent encapsulated in proteinoid microspheres which are stable to the environment encountered from the point of introduction until they migrate to the targeted body organs, fluids or ...

Tae G Park, Smadar Cohen, Robert S Langer: Controlled drug delivery using polymer/pluronic blends. Massachusetts Institute of Technology, Kilpatrick & Cody, July 19, 1994: US05330768 (340 worldwide citation)

A new series of degradable polymeric matrices were prepared by blending polymers that degrade by hydrolysis such as poly(L-lactic acid)(PLA), and nonionic Pluronic.TM. surfactants, block copolymers of polyethyleneoxide (PEO) and polypropyleneoxide (PPO). The water content of the polymer blend films ...

Rosemary L Smith, Scott D Collins: Electrochemical microsensors and method of making such sensors. Massachusetts Institute of Technology, Kilpatrick & Cody, October 17, 1989: US04874499 (319 worldwide citation)

Electrochemical microsensors formed of a substrate containing means for sensing potential or current, including active and passive electronic devices and electronic circuits, and a micromachined structure containing at least one cavity overlying the sensing means, wherein the structure and substrate ...

Wayne R Gombotz, Michael S Healy, Larry R Brown: Very low temperature casting of controlled release microspheres. Enzytech, Kilpatrick & Cody, May 28, 1991: US05019400 (302 worldwide citation)

A process for preparing microspheres using very cold temperatures to freeze polymer-biologically active agent mixtures into polymeric microspheres with very high retention of biological activity and material. Polymer is dissolved in a solvent together with an active agent that can be either dissolve ...

Abraham J Domb: Lipsopheres for controlled delivery of substances. Nova Pharmaceutical Corporation, Kilpatrick & Cody, February 23, 1993: US05188837 (273 worldwide citation)

A microsuspension system and method for its preparation is disclosed. The microsuspension contain lipospheres, which are solid, water-insoluble microparticles that have a layer of a phospholipid embedded on their surface. The core of the liposphere is a solid substance to be delivered, or a substanc ...