Charles D Jones: Antiestrogenic and antiandrugenic benzothiophenes. Eli Lilly and Company, Joseph A Jones, Arthur R Whale, November 29, 1983: US04418068 (394 worldwide citation)

6-Hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-piperidinoethoxy)benzoyl]benzo[b]thio phene, its ethers and esters, and the physiologically acceptable acid addition salts thereof, are valuable antiestrogens and antiendrogens.

Mary K Peters: Synthesis of acylated benzothiophenes. Eli Lilly and Company, Joseph A Jones, Arthur R Whale, April 19, 1983: US04380635 (236 worldwide citation)

A group of 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-aminoethoxy)benzoyl]benzo[b]thiophen es are prepared by acylation of a methyl-protected starting compound followed by demethylation in a single reaction mixture.

Jiban K Chakrabarti, Terrence M Hotten, David E Tupper: 2-methyl-thieno-benzodiazepine. Lilly, Joseph A Jones, Leroy Whitaker, MaCharri R Vorndran Jones, July 20, 1993: US05229382 (116 worldwide citation)

2-Methyl-10-(4-methyl-1-piperazinyl)-4H-thieno-[2,3-b][1,5]benzodiazepine, or an acid salt thereof, has pharmaceutical properties, and is of particular use in the treatment of disorders of the central nervous system. The compound has the following structure: ##STR1##




Ta Sen Chou, Laurie M Poteet, Douglas P Kjell: Stereoselective glycosylation process for preparing 2-Deoxy-2, 2-difluoronucleosides and 2-deoxy-2-fluoronucleosides. Eli Lilly and Company, Margaret M Brumm, Joseph A Jones, David E Boone, February 25, 1997: US05606048 (66 worldwide citation)

A stereoselective glycosylation process for preparing beta- and alpha-anomer enriched 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides by reacting a concentrated alpha- or beta-anomer enriched 2 -deoxy-2,2-difluorocarbohydrate or 2-deoxy-2 -fluorocarbohydrate with at least a mola ...

Charles D Jones, Mary E Goettel: Process for preparing 3-(4-aminoethoxybenzoyl)benzo[b]thiophenes. Eli Lilly and Company, Joseph A Jones, Arthur R Whale, November 9, 1982: US04358593 (66 worldwide citation)

The use of particularly advantageous protecting groups for the hydroxy groups of 6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophenes provides a high-yielding process for the preparation of such compounds having a 4-(2-aminoethoxy)benzoyl 3-group.

Ramakrishnan Nagarajan, Amelia A Schabel: Derivatives of A82846. Eli Lilly and Company, Kathleen R S Page, Joseph A Jones, James P Leeds, January 7, 1997: US05591714 (49 worldwide citation)

New N-alkyl and N-acyl derivatives of A82846A, A82846B, A82846C and PA-42867-A are provided. The new glycopeptide derivatives are useful for the treatment of susceptible bacterial infections, especially infections due to Gram-positive microorganisms.

Richard A Berglund: Asymmetric synthesis. Eli Lilly and Company, Joseph A Jones, November 8, 1994: US05362886 (48 worldwide citation)

This invention provides a stereospecific process for the synthesis of (S)-(+)-N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine, a key intermediate in the synthesis of duloxetine.

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