Daniel C F Chan, Paul Bunn, Dmitri Kirpotin: Hydrophilic microparticles and methods to prepare same. Kristine H Macheledt Bales & Johnson Johnson, April 11, 2000: US06048550 (53 worldwide citation)

The present invention comprises a material and a method of its preparation. The material may be described as hydrophilic microparticles, comprising a cluster of organic substance with a layer of polyelectrolyte on its surface. The present invention establishes an improved method for preparing aqueou ...

Frank A W Coumans, Jan Greve, Frank P Modica, Leon W M M Terstappen, Arjan G J Tibbe, John A Verrant: Methods and algorithms for cell enumeration in a low-cost cytometer. Veridex, Johnson & Johnson, Joseph F Aceto Esq, July 27, 2010: US07764821 (29 worldwide citation)

The enumeration of cells in fluids by flow cytometry is widely used across many disciplines such as assessment of leukocyte subsets in different bodily fluids or of bacterial contamination in environmental samples, food products and bodily fluids. For many applications the cost, size and complexity ...

Dmitri Kirpotin: Compound-loaded liposomes and methods for their preparation. Hermes Biosciences, Kristine H Macheledt Bales & Johnson Johnson, August 29, 2000: US06110491 (24 worldwide citation)

A liposome composition containing encapsulated compound in stable precipitated form, and a method for producing the composition, are disclosed. The concentration of precipitated compound within the liposomes is severalfold higher than that in the bulk medium, and the concentration of compound within ...

Michael Joseph Jay, G Thomas Kluemper, Sang Hun Kim: Formulations for sustained-release of topical anesthetics and methods of making and using same. University of Kentucky Research Foundation, Kristine H Macheledt Bales & Johnson Johnson, June 13, 2000: US06074674 (17 worldwide citation)

The present invention provides, inter alia, formulations useful to ameliorate symptoms associated with mucosal abrasions, specifically those due to dental orthodontic brackets; oral surgery; periodontal surgery or other procedures. For instance, there is a formulation comprising: 65 to 75% microcrys ...

Ian Ross Harris, Alexander M Harmon, Anthony J Kihm, Anna Gosiewska: Postpartum-derived cells for use in treatment of disease of the heart and circulatory system. DePuy Synthes Products, Philip J Johnson, Johnson & Johnson, April 22, 2014: US08703121 (10 worldwide citation)

Cells derived from postpartum tissue and methods for their use in treatment of diseases of the heart or circulatory system are disclosed. Cells may be used in either differentiated or undifferentiated forms, in homogenous cultures, or as populations with other cells, and in conjunction with other bi ...

Darin J Messina, Alexander M Harmon, Ian R Harris, Anthony J Kihm, Sanjay Mistry, Agnieszka Seyda, Chin Feng Yi, Anna Gosiewska: Regeneration and repair of neural tissue using postpartum-derived cells. DePuy Synthes Products, Philip S Johnson, Johnson & Johnson, February 25, 2014: US08658152 (9 worldwide citation)

Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of neural tissue using the postpartum-derived cells are also disclosed.

Ian R Harris, Darin J Messina, Anthony J Kihm, Agnieszka Seyda, David C Colter: Postpartum cells derived from umbilical tissue and methods of making and using the same. DePuy Synthes Products, Bernard F Plantz, Johnson & Johnson, August 26, 2014: US08815587 (8 worldwide citation)

Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described.

Kenneth Alan Simmen, Dominique Louis Nestor Ghislain Surleraux, Tse I Lin, Oliver Lenz, Pierre Jean Marie Bernard Raboisson, Sarvajit Chakravarty, Barry Patrick Hart: Fused bicyclic inhibitors of HCV. Tibotec Pharmaceuticals, Rajiv Shah Esquire, Johnson & Johnson, October 4, 2011: US08030318 (6 worldwide citation)

Substituted fused bicyclic pyrimidine compounds having an amide-substituted pyridylamine group at C-4 of the pyrimidine ring are useful in the treatment of conditions associated with HCV.

Dmitri Kirpotin, Daniel C F Chan, Paul Bunn: Cationic lipids and methods of use therefor. Kristine H Macheledt Bales & Johnson Johnson, November 9, 1999: US05980935 (6 worldwide citation)

The present invention relates generally to a non-toxic lipid conjugated with a cationic amino acid containing a guanidino group. Specifically, the naturally-occuring lipid DOPE is combined with the naturally-occurring amino acid Arginine. These compounds are useful for encapsulating and delivering p ...

Ilya Koyfman, Terry E Lawler, Robert C Di Luccio, Dennis D Jamiolkowski: High strength suture with absorbable core. Philip S Johnson, Johnson & Johnson, July 7, 2005: US20050149119-A1 (6 worldwide citation)

A novel high tensile strength semi-absorbable composite suture with minimized non-absorbable mass. The suture has a core made from a bioabsorbable polymer. The core is covered by a braided sheath. The braided sheath is made from an absorbable yarn and a bioabsorbable yarn. The bioabsorbable yarn is ...