1
Richard Axel, Michael H Wigler, Saul J Silverstein: Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials. The Trustees of Columbia University, John P White, August 16, 1983: US04399216 (687 worldwide citation)

The present invention relates to processes for inserting DNA into eucaryotic cells, particularly DNA which includes a gene or genes coding for desired proteinaceous materials for which no selective criteria exist. The insertion of such DNA molecules is accomplished by cotransforming eucaryotic cells ...


2
Marc Bessler, Michael R Treat: Gastrointestinal approximating and tissue attaching device. The Trustees of Columbia University in the City of New York, John P White, Peter J Phillips, May 2, 1995: US05411508 (625 worldwide citation)

An intestinal steerable endoscopic stapler for stapling tubular tissue is provided comprising a circular anvil member having a circular anvil stapling surface and a cutting block surface radially inwardly of the stapling surface. A head assembly has a circular staple driver for driving staples in an ...


3
Marc Bessler, Michael R Treat: Gastrointestinal endoscoptic stapler. The Trustees of Columbia University in the City of New York, John P White, Peter J Phillips, March 30, 1993: US05197649 (480 worldwide citation)

An intestinal steerable endoscopic stapler for stapling tubular tissue is provided comprising a circular anvil member having a circular anvil stapling surface and a cutting block surface radially inwardly of the stapling surface. A head assembly has a circular staple driver for driving staples in an ...


4
Shmuel Zalipsky: Active carbonates of polyalkylene oxides for modification of polypeptides. Enzon, John P White, Craig J Arnold, June 16, 1992: US05122614 (367 worldwide citation)

Poly(ethylene glycol)-N-succinimide carbonate and its preparation are disclosed. Polyethylene glycol (PEG) is converted into its N-succinimide carbonate derivative. This form of the polymer reacts readily with amino groups of proteins in aqueous buffers. The modified proteins have PEG-chains grafted ...


5
Richard Axel, Michael H Wigler, Saul J Silverstein: Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials. The Trustees of Columbia University in the City of New York, John P White, January 6, 1987: US04634665 (310 worldwide citation)

The present invention relates to processes for inserting DNA into eucaryotic cells, particularly DNA which includes a gene or genes coding for desired proteinaceous materials for which no selective criteria exist. The insertion of such DNA molecules is accomplished by cotransforming eucaryotic cells ...


6
Howard G Tennent: Carbon fibrils, method for producing same and compositions containing same. Hyperion Catalysis International, John P White, May 5, 1987: US04663230 (297 worldwide citation)

This invention concerns an essentially cylindrical discrete carbon fibril characterized by a substantially constant diameter between about 3.5 and about 70 nanometers, e.g. between about 7 and 25 nanometers, length greater than about 10.sup.2 times the diameter, an outer region of multiple essential ...


7
Martin Chalfie, Douglas Prasher: Uses of green-fluorescent protein. The Trustees of Columbia University in the City of New York, Woods Hole Oceanographic Institution, John P White, February 13, 1996: US05491084 (264 worldwide citation)

This invention provides a cell comprising a DNA molecule having a regulatory element from a gene, other than a gene encoding a green-fluorescent protein operatively linked to a DNA sequence encoding the green-fluorescent protein. This invention also provides a method for selecting cells expressing a ...


8
Richard Axel, Michael H Wigler, Saul J Silverstein: Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials. The Trustees of Columbia University in the City of New York, John P White, January 12, 1993: US05179017 (261 worldwide citation)

The present invention relates to processes for inserting DNA into eucaryotic cells, particularly DNA which includes a gene or genes coding for desired proteinaceous materials for which no selective criteria exist. The insertion of such DNA molecules is accomplished by cotransforming eucaryotic cells ...


9
W Clark Still, Michael H Wigler, Michael H J Ohlmeyer, Lawrence W Dillard, John C Reader: Complex combinatorial chemical libraries encoded with tags. The Trustees of Columbia University in the City of New York, Cold Spring Harbor Laboratory, John P White, October 15, 1996: US05565324 (259 worldwide citation)

Encoded combinatorial chemistry is provided, where sequential synthetic schemes are recorded using organic molecules, which define choice of reactant, and stage, as the same or different bit of information. Various products can be produced in the multi-stage synthesis, such as oligomers and syntheti ...


10
Lawrence S Bass, Steven K Libutti, Alexander M Eaton: Tissue bonding and sealing composition and method of using the same. The Trustees of Columbia University in the City of New York, John P White, May 11, 1993: US05209776 (257 worldwide citation)

Disclosed is a composition for bonding separated tissues together or for coating tissues or prosthetic materials including at least one natural or synthetic peptide and at least one support material which may be activated by energy.



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