1
Lynda M Sanders, Abraham Domb: Delayed/sustained release of macromolecules. Syntex, David A Lowin, John A Dhuey, September 25, 1990: US04959217 (261 worldwide citation)

This invention concerns novel, delayed/sustained release devices and compositions, including methods of their manufacture and use. The compositions include macromolecules, particularly polypeptide pharmaceuticals, and an initially partially-hydrated, non-biodegradable, hydrogel rate-limiting membran ...


2
David E Edgren, Shu Li, Gurdish Kaur Bhatti, Patrick S L Wong, Robert R Skluzacek: Extended release dosage form. Alza Corporation, John A Dhuey, Steven F Stone, June 12, 2001: US06245357 (176 worldwide citation)

A dosage form comprising a composition comprising a drug surrounded by an interior and an exterior wall with an exit for administering the drug to a patient; and a method of using the dosage form are disclosed for an indicated therapy.


3
Richard A Rauschenberger: Unitary sample-vent-valve assembly. Will Ross, John A Dhuey, July 10, 1979: US04160383 (161 worldwide citation)

A unitary sample-vent-valve assembly, useful in urological applications, is described. The unitary assembly comprises a sequential arrangement of valve, vent and sampling port to afford a compact unit.


4
Patrick S L Wong, Liang Chang Dong, David E Edgren, Felix Theeuwes, Phyllis I Gardner, Francisco Jao, Jason J Wan: Prolonged release active agent dosage form adapted for gastric retention. ALZA Corporation, John A Dhuey, Steven F Stone, September 19, 2000: US06120803 (150 worldwide citation)

The present invention is directed to an active agent dosage form which is adapted for retention in the stomach and useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a polymer matrix that swells upon contact with the fluids ...


5
Kevin J Brodbeck, Ann T Gaynor Duarte, Theodore Tao Ian Shen: Gel composition and methods. Alza Corporation, John A Dhuey, Steven F Stone, October 10, 2000: US06130200 (112 worldwide citation)

Methods and compositions for systemically or locally administering by implantation a beneficial agent to a subject are described, and include, for example, compositions having burst indices of 8 or less for systemic applications and systems releasing 10% or less of the total dose of beneficial agent ...


6
Terrence B Christensen, Allen D McNaughton, Steven R Umbach: Injection device. Syntex, John A Dhuey, Joseph I Hirsch, September 13, 1983: US04403989 (85 worldwide citation)

An injection device particularly suitable for the intraruminal injection of ruminants is described. The injection device is characterized by a needle carrying means and a needle actuation means, which are operatively coupled such that the needle actuation means permits movement of the needle carryin ...


7
Allen D McNaughton, Stephen B Albert, Gerard A Furbershaw: Implanting device and implant magazine. Syntex, John A Dhuey, Joseph I Hirsch, August 23, 1983: US04400170 (81 worldwide citation)

An implanting device for implanting pellets and like subcutaneously or intramuscularly in animals is described which utilizes means for indexing an implant magazine having a plurality of pellet-containing stations therein and means for automatically retracting a needle from about an implant charge t ...


8
Allen D McNaughton, Stephen B Albert, Gerard A Furbershaw: Implanting device and implant magazine. Syntex, John A Dhuey, Joseph I Hirsch, October 2, 1984: US04474572 (72 worldwide citation)

An implanting device for implanting pellets and like subcutaneously or intramuscularly in animals is described which utilizes means for indexing an implant magazine having a plurality of pellet-containing stations therein and means for automatically retracting a needle from about an implant charge t ...


9
Reginald Dyson: Body support means. G D Searle & Co, John A Dhuey, July 13, 1976: US03968530 (63 worldwide citation)

Pads and mattresses having novel aggregate fillers are described. Aggregates containing a highly viscous gel-like fluid and a mixture of re-expanded polystyrene beads and silica beads are utilized to produce lightweight pads and mattresses which provide support with favorable pressure distribution, ...


10
Donald F Munro, Robert R Burnside, Donald M Besemer: Syringe drive assembly. Syntex, John A Dhuey, May 23, 1989: US04833384 (59 worldwide citation)

An assembly is described for accurately and precisely controlling the position of a plunger in a syringe to deliver precise fluid volumes. The assembly includes a motor coupled to a lead screw that drives a bearing block along a linear guide rod to move the plunger of the syringe in a linear fashion ...