1
David Kanios: Compositions and methods to effect the release profile in the transdermal administration of active agents. Noven Pharmaceuticals, Jay G Kolman Esq, October 28, 2003: US06638528 (146 worldwide citation)

Compositions and methods for the transdermal delivery of active agents up to a period of seven days or more at substantially a zero-order release rate comprising a pharmaceutically acceptable adhesive matrix and a polymeric plastic material that provides a release rate regulating effect on the activ ...


2
William Neil Jones: Method of individually tracking and identifying a drug delivery device. Noven Pharmaceuticals, Jay G Kolman, Scott M Oldham, February 8, 2005: US06851615 (63 worldwide citation)

A method of and system for identifying an individual drug delivery device and tracing its ownership. An individual drug delivery device, such as a patch, is coded with a unique identifier. Such coding is performed by using a bar code or by storing the identifier in a memory device in the drug delive ...


3
Sylvia Rossi Montero, Juan Mantelle, David Kanios, David Houze: Solubility enhancement of drugs in transdermal drug delivery systems and methods of use. Noven Pharmaceuticals, Jay G Kolman, October 15, 2002: US06465004 (43 worldwide citation)

A composition and method for the continuous and controlled transdermal delivery of an active agent comprising a pharmaceutically acceptable active agent carrier and cellulose derivative which provides a solubilizing and stabilizing effect on the active agents incorporated therein.


4
David Kanios, Juan A Mantelle, David Houze: Barrier film lined backing layer composition and method for topical administration of active agents. Noven Pharmaceuticals, Jay G Kolman Esq, Scott M Oldham Esq, June 20, 2006: US07063859 (18 worldwide citation)

A transdermal drug delivery device for topical application of active agents is disclosed. The invention comprises the use of a flexible and soft backing layer, in particular a cellular foam, having an inner surface and an outer surface, wherein an impermeable polymeric barrier film is affixed to its ...


5
David P Kanios, Juan A Mantelle, Paul Johnson, Chensheng Li: Packaging system for transdermal drug delivery systems. Noven Pharmaceuticals, Jay G Kolman, June 14, 2005: US06905016 (17 worldwide citation)

A device and method for stabilizing a drug, particularly a chiral drug or the active enantiomer(s) thereof, in a carrier composition of a transdermal delivery system prior to the systems use by providing a product packaging system to prevent or control degradation reactions that can result from cert ...


6
Ronald E Laprade: Method and apparatus for making a patch. Noven Pharmaceuticals, Jay G Kolman Esq, July 17, 2001: US06261405 (1 worldwide citation)

A method and apparatus for making a patch comprising a foam supplier for supplying a foam backing having a predetermined porosity, a dispensing device for applying an ointment to the foam backing in a predetermined pattern, and a cooling device for cooling the foam backing prior to application of th ...


7
David Houze: Product positioning retention package. Noven Pharmaceuticals, Jay G Kolman Esq, May 16, 2006: US07044301

A product retention package is disclosed, wherein the package is configured to form a sealed internal cavity for receiving a product, particularly transdermal delivery systems, patches, bandages, films, sheets, and the like. A retention apparatus is formed in association with the cavity to maintain ...


8
David Houze: Product retention package. Noven Pharmaceuticals, Noven Pharmaceuticals, Jay G Kolman Esq, September 2, 2004: US20040168945-A1

A product retention package is disclosed, wherein the package is configured to form a sealed internal cavity for receiving a product, particularly transdermal delivery systems, patches, bandages, films, sheets, and the like. A retention means is formed in association with the cavity to maintain the ...


9
David Kanios: Packaging materials for transdermal drug delivery systems. Noven Pharmaceuticals, Noven Pharmaceuticals, Jay G Kolman Esq, July 22, 2004: US20040139705-A1

Compositions and methods for producing laminate materials in packaging a transdermal drug delivery system comprising a rubber modified acrylonitrile methyl acrylate copolymer film, alone or in combination with a polyester film, wherein the active drug incorporated in the transdermal system remains s ...


10
Rod Lawson Hartwig: Crystallization inhibition of drugs in transdermal drug delivery systems and methods of use. Noven Pharmaceuticals, Noven Pharmaceuticals, Jay G Kolman Esq, July 22, 2004: US20040142023-A1

The invention relates to compositions and methods for making a transdermal drug delivery system capable of achieving substantially zero-order kinetics for delivery of the active agent over a period of time in excess of 24 hours and at least 72 hours, comprising a pharmaceutically acceptable active a ...