1
Ernst B Hunziker: Method and compositions for the treatment and repair of defects or lesions in cartilage. Robert F Shaw, James F Haley Jr, Jane A Massaro, April 27, 1993: US05206023 (358 worldwide citation)

Methods and compositions are provided for the treatment and repair of defects or lesions in the cartilage of humans and other animals. The defect or lesion in the cartilage may be first treated with an enzyme to remove proteoglycans from the defect area. To induce cartilage formation, the defect is ...


2
Ernst B Hunziker: Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone. Robert Francis Shaw, Edward F Mullowney, Jane A Massaro, December 14, 1993: US05270300 (280 worldwide citation)

Methods and compositions are provided for the treatment and repair of defects in the cartilage or bone of humans and other animals as in full-thickness defects in joints. The defect in bone is filled with a matrix having pores large enough to allow cells to populate the matrix and to form blood vess ...


3
Ernst B Hunziker: Methods and compositions for the treatment and repair of defects or lesions in cartilage. Robert F Shaw, James F Haley Jr, Jane A Massaro, November 29, 1994: US05368858 (273 worldwide citation)

Methods and compositions are provided for the treatment and repair of defects or lesions in the cartilage of humans and other animals. The defect or lesion in the cartilage may be first treated with an enzyme to remove proteoglycans from the defect area. To induce cartilage formation, the defect is ...


4
Ernst B Hunziker: Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone using functional barrier. Robert Francis Shaw, Jane A Massaro, Mark J Rosen, Fish & Neave, December 29, 1998: US05853746 (161 worldwide citation)

Methods and compositions are provided for the treatment and repair of defects in the cartilage or bone of humans and other animals as in full-thickness defects in joints. To induce cartilage formation, a defect in cartilage is filled with a matrix having pores sufficiently large to allow cartilage r ...


5
Daniel Aeschlimann, Paul Bulpitt: Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same. Orthogene, Jane A Massaro, S Craig Rochester, Fish & Neave, October 7, 2003: US06630457 (47 worldwide citation)

Methods for chemical modification of hyaluronic acid, formation of amine or aldehyde functionalized hyaluronic acid, and the cross-linking thereof to form hydrogels are provided. Functionalized hyaluronic acid hydrogels of this invention can be polymerized in situ, are biodegradable, and can serve a ...


6
Alfred L Goldberg, Walter C Fiers, Isis C Kettelhut: Combinations of tumor necrosis factors and anti-inflammatory agents and methods for treating malignant and non-malignant diseases. Biogen, President and Fellows of Harvard College, James F Haley Jr, Leon R Yankwich, Jane A Massaro, December 25, 1990: US04980160 (23 worldwide citation)

This invention relates to combinations and methods for the treatment of malignant and non-malignant diseases. More particularly, this invention relates to combinations of natural or recombinant tumor necrosis factors ("TNF") and non-steroidal anti-inflammatory agents, such as indomethacin and ibupro ...


7
Elmar Maier, Igor Ivanov: Use of an osmolyte for reducing or abolishing no-covalent interactions of biological molecules to inert surfaces. Qiagen, Jane A Massaro Esq, Elinor Shin, Fish & Neave, November 21, 2000: US06150094 (7 worldwide citation)

The present invention relates to the use of an osmolyte for reducing or abolishing non-covalent interactions of biological molecules to inert surfaces. Furthermore, the present invention relates to kits that may be employed for uses in accordance with the present invention.


8
Yehuda Shoenfeld, Pnina Fishman: Immunotherapeutic method of treating cancerous diseases by administration of intravenous immunoglobulin. ARP Biomed, Jane A Massaro, Immac J Thampoe, Fish & Neave, October 8, 1996: US05562902 (1 worldwide citation)

This invention provides therapeutic methods for inhibiting tumor metastasis and for treating primary tumors. The methods of this invention do not cause serious side effects and will be effective for a broad spectrum of cancerous diseases. In particular, the invention discloses a novel method compris ...


9
Yehuda Shoenfeld, Pnina Fishman: Immunotherapeutic method of treating cancerous diseases by administration of gamma globulins. ARP Biomed, Jane A Massaro, Fish & Neave, October 12, 1999: US05965130

This invention provides therapeutic methods for inhibiting tumor metastasis and for treating primary tumors. The methods of this invention do not cause serious side effects and will be effective for a broad spectrum of cancerous diseases. In particular, the invention discloses a novel method compris ...