21
Arthur A Nagel, James P Rizzi, Terry J Rosen: Arylthiazolylimidazoles. Pfizer, Peter C Richardson, J Trevor Lumb, James M McManus, April 3, 1990: US04914207 (10 worldwide citation)

Arylthiazolylimidazoles as 5HT.sub.3 antagonists useful in the treatment of nausea, anxiety, pain, schizoprenia and gastrointestinal disorders.


22
Gene M Bright: Antibacterial 9-deoxo-9a-alkyl-9a-aza-9a-homoerythromycin A derivatives and intermediates therefore. Pfizer, Charles J Knuth, Albert E Frost, James M McManus, August 7, 1984: US04464527 (9 worldwide citation)

Antibacterial 9-deoxo-9a-ethyl and propyl-9a-aza-9a-homoerythromycin A compounds, pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising antibacterially effective amounts thereof and a pharmaceutically acceptable carrier, the treatment of bacterial infections with antibact ...


23
Kenneth Richardson, Geoffrey Gymer: Triazole antifungal agents. Pfizer, Charles J Knuth, Albert E Frost, James M McManus, November 20, 1984: US04483863 (9 worldwide citation)

Compounds of the general formula: ##STR1## wherein Ar is dichlorophenyl and Het is 1-methyltetrazol-5-yl, 1,2,4-triazol-3-yl, 1-methyl-1,2,4-triazol-3-yl, 2-methyl-1,2,4-triazol-3-yl, 4-methyl-1,2,4-triazol-3-yl, imidazol-2-yl or 1-methylimidazol-2-yl and their pharmaceutically acceptable acid addit ...


24
Rodney C Schnur, Anton F J Fliri: Benzamide protease inhibitors. Pfizer, Peter C Richardson, J Trevor Lumb, James M McManus, August 14, 1990: US04948901 (9 worldwide citation)

Compounds of the formula ##STR1## where HET is a heterocyclic group, n is an integer of 0 to 2 and R.sup.1 is hydrogen or lower alkyl are protease inhibitors useful as anti-plasmin and antithrombin agents.


25
Christopher A Lipinski: Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use. Pfizer, Charles J Knuth, Albert E Frost, James M McManus, March 11, 1986: US04575507 (9 worldwide citation)

Compounds related to 3',4'-dihydrospiro[imidazolidine-4,1'(2'H)-naphthalene]2,3',5-trione, spiro[chroman-4,4'-imidazolidine]2,2',5'-trione and 1',2'-dihydrospiro[imidazolidine-4,4'-(3'H)-quinoline 2,2'5-trione and reduced products thereof as aldose reductase inhibitors.


26
Yoshihiko Kitaura, Fumitaka Ito, Rodney W Stevens, Nobuko Asai: Antiallergy and antiinflammatory agents. Pfizer, Peter C Richardson, J Trevor Lumb, James M McManus, May 30, 1989: US04835166 (9 worldwide citation)

Compounds of the formula ##STR1## where Y is alkyl, aryl or heterocyclic, n is 1-7, R is hydrogen, alkyl, aralkyl or carboxymethyl, R.sub.1 is acetoxy, thiophenoxy, hydrogen, halo, alkyl, alkoxy or trifluoromethyl, R.sub.2 is hydrogen, alkyl or alkanoyl and X is C.dbd.O, CH.sub.2, NH, O or S as anti ...


27
James P Rizzi: Peptide immunostimulants. Pfizer, Peter C Richardson, Albert E Frost, James M McManus, August 30, 1988: US04767743 (8 worldwide citation)

Peptide components of formula 1, pharmaceutically acceptable base salts thereof, pharmaceutical compositions and their use as antiinfective agents ##STR1## where R.sub.1 is alkyl, cycloalkyl or cycloalkylmethyl; R.sub.2 is hydrogen or alkyl and R.sub.3 is hydroxy or an amino acid residu of the formu ...


28

29
Yoshihiko Kitaura, Fumitaka Ito, Rodney W Stevens, Nobuko Asai: Antiallergy and antiinflammatory agents. Pfizer, Peter C Richardson, J Trevor Lumb, James M McManus, February 27, 1990: US04904685 (7 worldwide citation)

Compounds of the formula ##STR1## where Y is alkyl, aryl or heterocyclic, n is 1-7, R is hydrogen, alkyl, aralkyl or carboxymethyl, R.sub.1 is acetoxy, thiophenoxy, hydrogen, halo, alkyl, alkoxy or trifluoromethyl, R.sub.2 is hydrogen, alkyl or alkanoyl and X is C.dbd.O, CH.sub.2, NH, O or S as anti ...


30
David Alker, Peter E Cross, Simon F Campbell: 4-aryl-3,5-bis(alkoxycarbonyl)-6-methyl -2-aminoalkyloxymethyl-1,4-dihydropyridine antihypertensive agents. Pfizer, Charles J Knuth, Albert E Frost, James M McManus, May 20, 1986: US04590195 (6 worldwide citation)

1,4-Dihydropyridine derivatives of the formula: ##STR1## wherein R is aryl or heteroaryl; R.sup.1 and R.sup.2 are each C.sub.1 -C.sub.4 alkyl or 2-methoxyethyl; n is 2, 3 or 4; R.sup.3 is H, C.sub.1 -C.sub.4 alkyl, CH.sub.2 CO.sub.2 (C.sub.1 -C.sub.4 alkyl) or CH.sub.2 CN; and R.sup.4 is a group of ...