1
Dennis J Hoover: Intermediates in polypeptide synthesis. Pfizer, Charles J Knuth, Albert E Frost, James M McManus, July 8, 1986: US04599198 (127 worldwide citation)

Bis(t-butoxycarbonyl) derivatives of phenylalanylhistidine as intermediates in the synthesis of rennin inhibiting polypeptides.


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Edward Davison, James I Wells: Pharmaceutically acceptable salts. Pfizer, Peter C Richardson, J Trevor Lumb, James M McManus, November 7, 1989: US04879303 (74 worldwide citation)

Improved pharmaceutical salts of amlodipine, particularly the besylate salt, and pharmaceutical compositions thereof. These salts find utility as anti-ischaemic and anti-hypertensive agents.


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Anibal Torres: Preparation and use of a highly purified polydextrose. Pfizer, Charles J Knuth, Albert E Frost, James M McManus, November 11, 1986: US04622233 (51 worldwide citation)

Methods for preparing purified, decolorized polydextrose having a lower caloric value, higher pH and less color than presently available commercial material, and the use of said improved product in edible foodstuffs and beverages.


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Gautam R Ranade: Generic zero order controlled drug delivery system. Pfizer, Peter C Richardson, J Trevor Lumb, James M McManus, December 20, 1988: US04792448 (40 worldwide citation)

A device for zero order releasing of biologically active substances into a fluid medium comprising a cylindrical tablet or bolus covered with an impermeable wall or coating from which strips of said wall or coating have been removed.


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Steven W Goldstein: Oxa- and thiazolidinedione hypoglycemic and hypocholesterolemic agents. Pfizer, Peter C Richardson, J Trevor Lumb, James M McManus, August 6, 1991: US05037842 (34 worldwide citation)

A series of 5-(4-[2-substituted benzoxazolylmethoxy]benzyl)oxa- and thiazolidine-2,4-diones as antidiabetic and cholesterol lowering agents.


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Michael S Kellogg: Derivatives of 6.beta.-hydroxyalkylpenicillanic acids as .beta.-lactamase inhibitors. Pfizer, Charles J Knuth, Peter C Richardson, James M McManus, September 1, 1981: US04287181 (24 worldwide citation)

6.beta.-Hydroxyalkylpenicillanic acids and derivatives thereof as useful enhancers of the effectiveness of several .beta.-lactam antibiotics against many .beta.-lactamase producing bacteria, and 6.beta.-substituted penicillanic acid benzyl ester derivatives as useful intermediates leading to said ag ...


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Dennis J Hoover, Robert L Rosati, Ronald T Wester: Nor-statine and nor-cyclostatine polypeptides. Pfizer, Peter C Richardson, J Trevor Lumb, James M McManus, July 23, 1991: US05034376 (21 worldwide citation)

Polypeptides and derivatives thereof containing nor-statine and nor-cyclostatine are useful for inhibiting the angiotensinogen-cleaving action of the enzyme renin.


9
Dennis J Hoover, Robert L Rosati, Ronald T Wester: Nor-statine and nor-cyclostatine polypeptides. Pfizer, Peter C Richardson, J Trevor Lumb, James M McManus, March 21, 1989: US04814342 (19 worldwide citation)

Polypeptides and derivatives thereof containing nor-statine and nor-cyclostatine are useful for inhibiting the angiotensinogen-cleaving action of the enzyme renin.


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Yoshihiko Kitaura, Fumitaka Ito, Rodney W Stevens, Nobuko Asai: Antiallergy and antiinflammatory agents, compositions and use. Pfizer, Peter C Richardson, J Trevor Lumb, James M McManus, July 30, 1991: US05036088 (19 worldwide citation)

Compounds of the formula ##STR1## where Y is alkyl, aryl or heterocyclic, n is 1-7, R is hydrogen, alkyl, aralkyl or carboxymethyl, R.sub.1 is acetoxy, thiophenoxy, hydrogen, halo, alkyl, alkoxy or trifluoromethyl, R.sub.2 is hydrogen, alkyl or alkanoyl and X is C.dbd.O, CH.sub.2, NH, O or S as anti ...