1
Elmén Joacim, Kearney Phil, Kauppinen Sakari: Pharmaceutical compositions comprising anti-mirna antisense oligonucleotides. Santaris Pharma, Elmén Joacim, Kearney Phil, Kauppinen Sakari, INSPICOS, October 11, 2007: WO/2007/112754 (132 worldwide citation)

The invention provides pharmaceutical compositions comprising short single stranded oligonucleotides, of length of between 8 and 17 nucleobases which are complementary to human microRNAs. The short oligonucleotides are particularly effective at alleviating miRNA repression in vivo. It is found that ...


2
Andreasen Jørgen, Videbæk Karsten, Gundberg Tomas, Larsen Lars Erup: Tissue sample collection system with visual sample inspection. Sonion Roskilde, Andreasen Jørgen, Videbæk Karsten, Gundberg Tomas, Larsen Lars Erup, INSPICOS, October 11, 2007: WO/2007/112751 (101 worldwide citation)

A biopsy device for harvesting at least one tissue sample from a body of a living being comprises a hollow needle (110) with an end portion adapted to be introduced into the body, and a cutting mechanism for severing the tissue sample. A sample-receiving device is provided for receiving the severed ...


3
Jensen Bo Vestergård: Method and apparatus for reversing a piston rod in an injection device. Novo Nordisk, Jensen Bo Vestergård, INSPICOS, August 31, 2006: WO/2006/089547 (51 worldwide citation)

The present invention relates to a method and an apparatus for reversing a piston rod in an injection device, the piston rod being operatively connected to a motor shaft of an electrical motor so that a rotational movement of the motor shaft is transformed to a translational movement of the piston r ...


4
Elmén Joacim, Kearney Phil, Kauppinen Sakari: Pharmaceutical composition comprising anti-mirna antisense oligonucleotides. Santaris Pharma, Elmén Joacim, Kearney Phil, Kauppinen Sakari, INSPICOS, October 11, 2007: WO/2007/112753 (50 worldwide citation)

The invention provides pharmaceutical compositions comprising short single stranded oligonucleotides, of length of between 8 and 26 nucleobases which are complementary to human microRNAs selected from the group consisting of miR19b, miR21, miR122a, miR155 and miR375. The short oligonucleotides are p ...


5
Litman Thomas, Moller Soren, Echwald Soren Morgenthaler, Jacobsen Nana, Glue Christian: Detection of tissue origin of cancer. Exiqon, Litman Thomas, Moller Soren, Echwald Soren Morgenthaler, Jacobsen Nana, Glue Christian, Inspicos, July 5, 2007: WO/2007/073737 (43 worldwide citation)

Disclosed is a method for determining the cellular or tissue origin of tumor cells. The method entails determining the presence of at least one micro RNA (miRNA) in a sample derived from tumor tissue and based on the said determination establishing a miRNA expression profile and comparing this with ...


6
Oleksiewicz Martin B, Nielsen Lars S, Andersen Peter S, Hansen Margit H: Method for linking sequences of interest. Symphogen, Oleksiewicz Martin B, Nielsen Lars S, Andersen Peter S, Hansen Margit H, INSPICOS, May 12, 2005: WO/2005/042774 (36 worldwide citation)

Multiplex overlap-extension RT-PCR provides an efficient method of linking two or more nucleotide sequences encoding for domains or subunits of a heteromeric protein, in a single reaction. Especially, the linkage of variable region encoding sequences from e.g. immunoglobulins, T cell receptors or B ...


7
Christensen Søren Flygenring, Jensen Ole Staus: Spherical radiofrequency-encoded beads. Versamatrix, Christensen Søren Flygenring, Jensen Ole Staus, INSPICOS, January 12, 2006: WO/2006/002641 (36 worldwide citation)

The invention relates to a method for the production of a composition comprising a plurality of spherical radiofrequency-identifiable (RF-tagged) polymeric beads as well the composition as such. The invention also relates to an apparatus for analyzing, identifying or sorting as well as treating a pl ...


8
Nielsen Brian, Frederiksen Jesper Mads Bartroff, Larsen Truels Sterm, Jepsen Erik Lund, Hvid Niels, Budig Klaus: Pump and system for treatment of a wound. Coloplast, Nielsen Brian, Frederiksen Jesper Mads Bartroff, Larsen Truels Sterm, Jepsen Erik Lund, Hvid Niels, Budig Klaus, INSPICOS, August 9, 2007: WO/2007/087808 (34 worldwide citation)

A pump for pumping fluid matter from a treatment site in or on a living being comprises three compartments. A motor-driven pumping element is provided for generating a negative pressure within a wound cover at or near the treatment site, and a motor for providing a driving force to the pumping eleme ...


9
Videbæk Karsten: Firing system for biopsy device. Sonion Roskilde, Danborg Innovation, Videbæk Karsten, INSPICOS, January 19, 2006: WO/2006/005342 (33 worldwide citation)

A biopsy system for harvesting tissue samples from a suspect tissue mass in a body of a living being, e.g. in percutaneous aspiration biopsy, comprises a hollow needle (50) and a sample-receiving device (52), which is movable in the hollow needle. A first user-operable firing mechanism (110) is prov ...


10
Jacobsen Nana, Kongsbak Lars, Kauppinen Sakari, Echwald Søren Morgenthaler, Mouritzen Peter, Nielsen Peter Stein, Nørholm Mikkel: Methods for quantification of micrornas and small interfering rnas. Exiqon, Jacobsen Nana, Kongsbak Lars, Kauppinen Sakari, Echwald Søren Morgenthaler, Mouritzen Peter, Nielsen Peter Stein, Nørholm Mikkel, INSPICOS, October 20, 2005: WO/2005/098029 (33 worldwide citation)

The invention relates to ribonucleic acids, probes and methods for detection, quantification as well as monitoring the expression of mature microRNAs and small interfering RNAs (siRNAs). The invention furthermore relates to methods for monitoring the expression of other non-coding RNAs, mRNA splice ...



Click the thumbnails below to visualize the patent trend.