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Tarran Jones
LAROSA GREGORY J, HORVATH CHRISTOPHER, NEWMAN WALTER, JONES S TARRAN, O BRIEN SIOBHAN, O KEEFE THERESA: ANTICORPS HUMANISES ANTI-CCR2 ET PROCEDES DUTILISATION DE CES ANTICORPS, HUMANIZED ANTI-CCR2 ANTIBODIES AND METHODS OF USE THEREFOR. MILLENNIUM PHARMACEUTICALS, MILLENNIUM PHARMACEUTICALS, GOWLING LAFLEUR HENDERSON, May 21, 2013: CA2399080

The present invention relates to a humanized antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor (2) (CCR2) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the inte ...


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Kevin Rodzinak
Armstrong Donna J, Hu Essa H, Kelly Michael J Iii, Layton Mark E, Li Yiwei, Liang Jun, Rodzinak Kevin J, Rossi Michael A, Sanderson Philip E, Wang Jiabing: Inhibiteurs de lactivite akt, Inhibitors of akt activity. Merck & Co, Merck Sharp & Dohme, Gowling Lafleur Henderson, February 8, 2011: CA2610888

The instant invention provides for substituted naphthyridine compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt ...


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Eric First, M.D.
FIRST ERIC R: COMPOSITIONS COSMETIQUES DE NEUROTOXINE COMPRENANT UN COMPOSANT DE TOXINE BOTULINIQUE, ET PROCEDES CORRESPONDANTS, COSMETIC NEUROTOXIN COMPOSITIONS COMPRISING A BOTULINUM TOXIN COMPONENT AND METHODS. ALLERGAN, ALLERGAN, GOWLING LAFLEUR HENDERSON, April 2, 2013: CA2582974

Cosmetic compositions include a Clostridial neurotoxin component and a microsphere component. In certain compositions, the composition includes a botulinum toxin and a plurality of swellable microspheres. The compositions are administered to individuals, by injection and the like, to treat a cosmeti ...


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Piotr Konrad Tysowski: Method of downloading ephemeris data based on user activity. Research In Motion, Gowling Lafleur Henderson, Matthew Roy, Mark Sprigings, December 15, 2009: US07633438 (130 worldwide citation)

Ephemeris data is downloaded intelligently to a GPS-enabled wireless communications device based on user activity rather than at fixed predetermined intervals. Ephemeris data can be downloaded to enable both Aided GPS and Assisted GPS. The device can download ephemeris data based on the frequency of ...


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Bruce A J Skinner: Biopsy needle for a biopsy instrument. Biopsy Needle Partnership, Gowling Lafleur Henderson, November 13, 2001: US06315737 (107 worldwide citation)

A biopsy needle with a conduit for receiving a hard biopsy sample and a fluid biopsy sample. The conduit has a first cross-sectional area. The biopsy needle has an end with a penetrating bit operable for coring the hard biopsy sample. The end has a second cross-sectional area less than the first cro ...


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John Hayman, Shaun Johansen, Jon David Lacey, Jay Steele: Parametric geometric element definition and generation system and method. Gowling Lafleur Henderson, March 25, 2003: US06538651 (105 worldwide citation)

A parametric geometric element definition and generation system and method is described herein. 3D model of geometric objects are generated by execution of one or more directed acyclic graphs having a plurality of nodes which represent various modeling operations and parameters or properties used in ...



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