1
Arthur Schleifer, May Tom Moy: Method of producing oligonucleotide arrays with features of high purity. Agilent Technologies, Elizabeth E Leitereg, Gordon Stewart, June 20, 2000: US06077674 (227 worldwide citation)

A method of making full-length oligonucleotide arrays provides for the purification of pre-synthesized full-length oligonucleotides from shorter length oligonucleotides and other impurities at the same time the oligonucleotides are deposited on the array. A synthesized mixture that includes desired ...


2
Arthur Schleifer, Carol T Schembri, Michael P Caren: Preparation of biopolymer arrays. Agilent Technologies, Gordon Stewart, June 5, 2001: US06242266 (117 worldwide citation)

A method and apparatus for fabricating an array of biopolymers on a substrate using a biopolymer or biomonomer fluid, and using a fluid dispensing head. The head has at least one jet which can dispense droplets onto a substrate, the jet including a chamber with an orifice, and including an ejector w ...


3
J Fleming Dias, Ganapati R Mauze: Noninvasive blood chemistry measurement method and system. Agilent Technologies, Ted Leitereg, Gordon Stewart, September 5, 2000: US06113541 (114 worldwide citation)

A noninvasive blood chemistry measurement method and system isolate measurement contributions due to a patient's blood to accurately measure blood chemistry. In accordance with a first preferred embodiment of the present invention a noninvasive blood chemistry measurement method decreases the blood ...


4
William D Fisher: Biopolymer array inspection. Agilent Technologies, Gordon Stewart, May 15, 2001: US06232072 (107 worldwide citation)

A method of fabricating a biopolymer array, and an apparatus which can execute the method. droplets of fluid carrying the biopolymer or a biomonomer are deposited onto a front side of a transparent substrate. Light is directed through the substrate from the front side, back through a substrate back ...


5
Herbert F Cattell: Chemical array fabrication with identifier. Agilent Technologies, Gordon Stewart, January 30, 2001: US06180351 (87 worldwide citation)

A method of generating an addressable array of biopolymers, such as DNA probes, on a substrate. The method includes receiving from a remote station, information on a layout of the array and an associated first identifier. A local identifier is generated corresponding to the first identifier and asso ...


6
Michel G M Perbost: Methods of making polymeric arrays. Agilent Technologies, Gordon Stewart, January 9, 2001: US06171797 (79 worldwide citation)

Methods are provided for making arrays of distinct polymers covalently bonded to the surface of the a solid support. In the subject methods, at least two distinct polymers, e.g. nucleic acids, are contacted with the surface of a solid support under conditions sufficient for the nucleic acids to beco ...


7
Michael P Caren, Carol T Schembri, Peter G Webb: Fabricating biopolymer arrays. Agilent Technologies, Gordon Stewart, November 27, 2001: US06323043 (67 worldwide citation)

A method and apparatus for fabricating an array of biopolymers on a substrate using a biopolymer or biomonomer fluid, and using a dispensing head. The head has a reservoir chamber and at least one jet which can dispense droplets onto a substrate. The jet includes a capillary delivery chamber communi ...


8
Douglas J Dellinger, SueAnn C Dahm, Diane D Ilsley, Robert A Ach, Mark A Troll: Hybridization assay signal enhancement. Agilent Technologies, Bill Kennedy, Gordon Stewart, August 15, 2000: US06103474 (56 worldwide citation)

A signal amplification method for detecting a target nucleic acid analyte having a homopolymeric region and a target sequence includes steps of: contacting an analyte under hybridizing conditions with a multiplicity of reporter probes, each reporter probe including a signal region and an oligonucleo ...


9
Carol T Schembri, Leslie B Overman, Charles Z Hotz: Apparatus for conducting chemical or biochemical reactions on a solid surface within an enclosed chamber. Agilent Technologies, Gordon Stewart, July 10, 2001: US06258593 (52 worldwide citation)

The invention provides an apparatus and method for conducting chemical or biochemical reactions on a solid surface within an enclosed chamber. The invention may be used in conducting hybridization reactions, as of biopolymers such as DNA, RNA, oligonucleotides, peptides, polypeptides, proteins, anti ...


10
Nicholas M Sampas: CCD imager for confocal scanning microscopy. Agilent Technologies, Gordon Stewart, July 4, 2000: US06084991 (47 worldwide citation)

A CCD array imager adapted for use as a spatial noise discriminator in confocal scanning microscopy comprises a parallel (vertical) register with a horizontal unmasked imaging row of pixels in tandem with a masked storage array, a serial (horizontal) register for readout, and a means for synchronizi ...