1
Parker Jacqueline N, Whitley Richard J, Markert James M: Methods and compositions for cytokine expression and treatment of tumors. Uab Research Foundation, Parker Jacqueline N, Whitley Richard J, Markert James M, GOLDSTEIN Avery N, May 11, 2006: WO/2006/050274 (10 worldwide citation)

A conditionally replicating, aneurovirulent recombinant herpes simplex virus is provided that includes a nucleic acid encoding an expressible chemokine. An expression control element is operably linked to the nucleic acid. A therapeutic composition includes a first conditionally replicating, aneurov ...


2
Joseph Richard, Dimeo James: Assay and process for labeling and detection of micro rna and small interfering rna sequences. Perkinelmer Las, Joseph Richard, Dimeo James, GOLDSTEIN Avery N, January 13, 2005: WO/2005/003318 (7 worldwide citation)

A process for protecting a short RNA fragment includes labeling a short RNA fragment with a detectable platinum compound forming a labeled small RNA fragment. Resulting labeled short RNA fragment is exposed to a capture oligonucleotide. The capture oligonucleotide includes at least two replicates of ...


3
PARKER WILLIAM B: Purine nucleoside phosphorylase as enzymatic activator of nucleoside prodrugs. The Uab Research Foundation, Goldstein Avery N, February 18, 2010: WO/2010/019954 (7 worldwide citation)

A process for inhibiting a mammalian cancerous cell or virally infected cell includes providing a Trichomonas vaginalis purine nucleoside phosphorylase enzyme or a tail mutant purine nucleoside phosphorylase enzyme in proximity to the mammalian cancerous cell or the virally infected cell and exposin ...


4
Cerda Blas: Substrates and internal standards for mass spectroscopy detection. Perkinelmer Las, Cerda Blas, GOLDSTEIN Avery N, September 20, 2007: WO/2007/106816 (4 worldwide citation)

An inventive substrate is provided which includes a substrate compound of formula A - B1 - B2 - B3: wherein A is a sugar moiety; B1 is a linker moiety allowing the conjugation of moiety A and the remaining structure of the substrate; B2 contains a permanently charged element such as a quaternary amm ...


5
WANG KEVIN KA WANG: Micro-rna, autoantibody and protein markers for diagnosis of neuronal injury. BANYAN BIOMARKERS, Goldstein Avery N, March 17, 2011: WO/2011/032155 (4 worldwide citation)

Processes and materials are provided for the detection, diagnosis, or determination of the severity of a neurological injury or condition, including traumatic brain injury, multiple-organ injury, stroke, Alzeimer's disease, Pakinson disease and Chronic Traumatic Encephalopathy (CTE),. The processes ...


6
Keller Charles, Bahadur Ali N: Process and apparatus for imaging. The University Of Texas, Keller Charles, Bahadur Ali N, GOLDSTEIN Avery N, August 9, 2007: WO/2007/089641 (3 worldwide citation)

Processes for producing a microCT image for virtual histology using x-ray microscopic computed tomography are described along with processes for rapid and inexpensive high- throughput methods of high resolution imaging for screening an ex vivo embryo for phenotype using computed tomography imaging. ...


7
Meythaler Jay M: A zwitterion solution for low-volume therapeutic delivery. Wayne State University Board Of Governors, Meythaler Jay M, GOLDSTEIN Avery N, December 24, 2008: WO/2008/157308 (3 worldwide citation)

A formulation is provided that includes a volume of an aqueous multivalent physiological ion solution compatible with cerebrospinal fluid containing at least one divalent cation of magnesium or calcium, and at least one anion of carbonate or phosphate, and having a pH between 6.5 and 8.0. A zwitteri ...


8
Khoury Michael D: Vascular endograft. Khoury Michael D, GOLDSTEIN Avery N, August 24, 2006: WO/2006/088905 (3 worldwide citation)

An endograft for a vessel having a vascular branch extending from the vessel is provided. The endograft includes a main body having a wall separating interior and exterior surfaces and adapted to be inserted within the vessel. The main body is characterized by a single proximal opening and a single ...


9
Goldstein Avery N: Metal nanocrystals and synthesis thereof. Nanospin Solutions, GOLDSTEIN Avery N, February 26, 2004: WO/2004/016376 (2 worldwide citation)

A process for forming metal nanocrystals involves complexing a metal ion and an organic ligand in a solvent and introducing a reducing agent to reduce a plurality of metal ions to form the metal nanocrystals associated with the organic ligand. The nanocrystals are optionally doped or alloyed with ot ...


10
Boyer Anne E, Quinn Conrad P, Barr John R: Detection of anthrax pathogenicity factors. The Government Of The United States Of, America Represented By, The Secretary Department Of The Health And Human Services Centers For Disease Control And Prevention, Boyer Anne E, Quinn Conrad P, Barr John R, GOLDSTEIN Avery N, November 29, 2007: WO/2007/136436 (2 worldwide citation)

One major problem in diagnosis methods presently available for anthrax is that these methods require several days to produce a result. The only existing treatment for anthrax requires administration soon after infection at a time when patients are exhibiting only mild flu- like symptoms. Thus, a pat ...



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