1
Robert Fahrner, Deborah Follman, Benedicte Lebreton, Robert van Reis: Non-affinity purification of proteins. Genentech, Deirdre L Conley, Ginger R Dreger Esq, Heller Ehrman, January 29, 2008: US07323553 (69 worldwide citation)

The present invention relates to a method for protein purification that involves the combination of non-affinity chromatography with HPTFF.


2

3
Mark X Sliwkowski: Treating prostate cancer with anti-ErbB2 antibodies. Genentech, Wendy Lee, Ginger R Dreger Esq, Heller Ehrman, May 9, 2006: US07041292 (37 worldwide citation)

The present application discloses treatment of prostate cancer with anti-ErbB2 antibodies.


4
Roland Buelow, Josef Platzer, Wim van Schooten, Jens Ulrich Buelow: Production of humanized antibodies in transgenic animals. Therapeutic Human Polyclonals, Ginger R Dreger Esq, Heller Ehrman, October 31, 2006: US07129084 (33 worldwide citation)

This invention relates to humanized antibodies and antibody preparations produced from transgenic non-human animals. The non-human animals are genetically engineered to contain one or more humanized immunoglobulin loci which are capable of undergoing gene rearrangement and gene conversion in the tra ...


5
Paul J Carter, John B Ridgway: Antibodies for cancer therapy and diagnosis. Genentech, Craig Svoboda Esq, Ginger R Dreger Esq, Heller Ehrman, October 30, 2007: US07288249 (30 worldwide citation)

The present application describes a method for making antibodies which can be used for cancer diagnosis or therapy. The application also discloses a method for identifying an antigen which is differentially expressed on the surface of two or more distinct cell populations. The application additional ...


6
David Botstein, Audrey Goddard, Paul J Godowski, Austin L Gurney, Margaret Ann Roy, William I Wood: Secreted and transmembrane polypeptides and nucleic acids encoding the same. Genetech, Mark T Kresnak, Elizabeth M Barnes, Ginger R Dreger Esq, July 5, 2005: US06913919 (24 worldwide citation)

The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to het ...


7
Avi Ashkenazi, Sherman Fong, Audrey Goddard, Austin L Gurney, Mary A Napier, Daniel Tumas, Menno Van Lookeren, William I Wood: Treatment of inflammatory disorders with STIgMA immunoadhesins. Genentech, Mark T Kresnak, Elizabeth M Barnes, Ginger R Dreger Esq, March 20, 2007: US07192589 (20 worldwide citation)

The present invention relates to compositions and methods of treating and diagnosing disorders characterized the by the presence of antigens associated with inflammatory diseases and/or cancer.


8

9
Daniel E Afar, Rene S Hubert, Kahan Leong, Arthur B Raitano, Douglas C Saffran, Stephen Chappell Mitchell: Antibodies immunospecific for STEAP1. Agensys, Ginger R Dreger Esq, Deirdre L Conley, Shane M Popp LLM, May 30, 2006: US07053186 (18 worldwide citation)

Described is a novel family of cell surface serpentine transmembrane antigens. Two of the proteins in this family are exclusively or predominantly expressed in the prostate, as well as in prostate cancer, and thus members of this family have been termed “STRAP” (serpentine transmembrane antigens of ...


10
James Andya, Jeffrey L Cleland, Chung C Hsu, Xanthe M Lam, David E Overcashier, Steven J Shire, Janet Yu Feng Yang, Sylvia Sau Yan Wu: Protein formulation. Genentech, Atulya Agarwal Esq, Ginger R Dreger Esq, Arnold & Porter, March 23, 2010: US07682609 (17 worldwide citation)

A stable lyophilized protein formulation is described which can be reconstituted with a suitable diluent to generate a high protein concentration reconstituted formulation which is suitable for subcutaneous administration. For example, anti-IgE and anti-HER2 antibody formulations have been prepared ...