1
Mark B Chandler, Don J Chandler: Microparticles attached to nanoparticles labeled with flourescent dye. Luminex Corporation, Gilberto M Villacorta, Pepper Hamilton, July 31, 2001: US06268222 (288 worldwide citation)

This invention provides a novel fluorescent article comprising a core or carrier particle having on its surface a plurality of smaller polymeric particles or nanoparticles, which are stained with different fluorescent dyes. When excited by a light source they are capable of giving off multiple fluor ...


2
Van S Chandler: Multi-analyte diagnostic system and computer implemented process for same. Luminex Corporation, Gilberto M Villacorta, Robert R Seabold, Katten Muchin Zavis Rosenman, July 15, 2003: US06592822 (159 worldwide citation)

A multi-analyte diagnostic system for use with a computer. The diagnostic system includes a flow analyzer including a co-planar light source-optical detector array, the flow analyzer being communicatable with the computer. The diagnostic system also includes a memory medium readable by the computer ...


3
Van S Chandler, R Jerrold Fulton, Mark B Chandler: Multiplexed analysis of clinical specimens apparatus and method. Luminex Corporation, Gilberto M Villacorta, Serge Sira, Katten Muchin Zavis Rosenman, February 25, 2003: US06524793 (158 worldwide citation)

A method for the multiplexed diagnostic and genetic analysis of enzymes, DNA fragments, antibodies, and other biomolecules comprises the steps of constructing an appropriately labeled beadset, exposing the beadset to a clinical sample, and analyzing the combined sample/beadset by flow cytometry. Flo ...


4
Van S Chandler, Jerrold R Fulton, Mark B Chandler: Multiplexed analysis of clinical specimens apparatus and method. Luminex Corporation, Gilberto M Villacorta, Pepper Hamilton, September 10, 2002: US06449562 (127 worldwide citation)

A method for the multiplexed diagnostic and genetic analysis of enzymes, DNA fragments, antibodies, and other biomolecules comprises the steps of constructing an appropriately labeled beadset, exposing the beadset to a clinical sample, and analyzing the combined sample/beadset by flow cytometry is d ...


5
James Korein, Shree K Nayar, L Clayton Yaseen II, Venkata N Peri: Adjustable imaging system with wide angle capability. Cyclo Vision Technologies, Gilberto M Villacorta, Pepper Hamilton, May 1, 2001: US06226035 (120 worldwide citation)

Optical systems are disclosed that enable an image sensor to generate an image of either a wide-angle view of an area of interest, or a direct view of an area of interest. In an embodiment, a wide-angle optical system is mounted to reflect radiation reflected from the area of interest along an optic ...


6
Mark R Stiegemeier, Cory L Hacking: Single-document active user interface, method and system for implementing same. MEGG Associates, Gilberto M Villacorta, Pepper Hamilton, February 20, 2001: US06192381 (114 worldwide citation)

A data management system user interface allows users to enter, store, retrieve, and display multiple, related groups of information in a single document. The interface loads document data into a separate template which defines various fields, and the interface determines the fields that should be di ...


7
Don J Chandler, Beth A Lambert, Janet J Reber, Stacie L Phipps: Precision fluorescently dyed particles and methods of making and using same. Luminex Corporation, Gilberto M Villacorta, Pepper Hamilton, February 4, 2003: US06514295 (100 worldwide citation)

An improved method of making a series of bead or microsphere or particle populations characterized by subtle variation in a proportion or ratio of at least two fluorescent dyes distributed within a single bead of each population is provided. These beads, when excited by a single excitation light sou ...


8
Don J Chandler: Encapsulation of discrete quanta of fluorescent particles. Luminex Corporation, Gilberto M Villacorta, Serge Sira, Katten Muchin Zavis Rosenman, March 4, 2003: US06528165 (96 worldwide citation)

The present invention provides novel encapsulation compositions and methods. In particular, the invention relates to fluorescent capsule compositions, which consists of a layer of a polymer shell enclosing one or more fluorescent materials such as fluorescent microspheres and which are capable of em ...


9
Cindra A Widrig Opalsky, David Opalsky, Andy Maczuszenko, Imants R Lauks, Rhonda J Cheadle: Apparatus and method for assaying coagulation in fluid samples. i STAT Corporation, Gilberto M Villacorta, Robert W Hahl, Katten Muchin Zavis Rosenman, June 15, 2004: US06750053 (89 worldwide citation)

This invention is a disposable cartridge for use at the patient side to perform traditional coagulation assays on fresh whole blood or blood derivative samples. The cartridge, in use with an electronic analyzer allows a fluid sample to be metered and quantitatively mixed with reagents which activate ...


10
Van S Chandler: Diode laser based measurement apparatus. Luminex Corporation, Gilberto M Villacorta, Suresh Pepper Hamilton Koshy, April 4, 2000: US06046807 (78 worldwide citation)

The instant diagnostic system includes a measurement device including a laser diode and communicatable with a computer. The diagnostic system further includes a memory medium readable by the computer and storing computer instructions executable by the computer. The instructions include the following ...