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Marvin H Caruthers, Mark D Matteucci: Process for preparing polynucleotides. University Patents, George M Yahwak, July 3, 1984: US04458066 (892 worldwide citation)

New and useful intermediate nucleotides bound to an inorganic polymer support, including the preparation thereof, and processes for the conversion to oligonucleotides which are especially useful for the synthesis of polynucleotides, particularly ribonucleic (RNA) and deoxyribonucleic acids (DNA).


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Marvin H Caruthers, Mark D Matteucci: Nucleosides useful in the preparation of polynucleotides. University Patents, George M Yahwak, February 19, 1985: US04500707 (362 worldwide citation)

New and useful intermediate nucleotides bound to an inorganic polymer support, including the preparation thereof, and processes for the conversion to oligonucleotides which are especially useful for the synthesis of polynucleotides, particularly ribonucleic (RNA) and deoxyribonucleic acids (DNA).


3
Ebtisam Wilkins: Membrane electrode for non-ionic species. University Patents, George M Yahwak, April 3, 1984: US04440175 (289 worldwide citation)

Concentrations of non-ionic species in aqueous media are measured as a function of potentiometric or polarographic response, employing a membrane electrode selective for the non-ionic species being measured. The electrode comprises a conductive substrate and a membrane formed as a layer on the condu ...


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Marvin H Caruthers, Serge L Beaucage: Phosphoramidite nucleoside compounds. University Patents, George M Yahwak, May 26, 1987: US04668777 (236 worldwide citation)

A new class of nucleoside phosphoramidites which are relatively stable to permit isolation thereof and storage at room temperature. The phosphoramidites are derivatives of saturated secondary amines.


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David J Graves, Mark A Burns: Affinity chromatography using dried calcium alginate-magnetite separation media in a magnetically stabilized fluidized bed. University Patents, George M Yahwak, June 23, 1987: US04675113 (70 worldwide citation)

Disclosed is a method of conducting affinity chromatographic separations of biomaterials which comprises contacting the biomaterial with a solid support comprising a generally spherical bead having a generally central magnetic core and a surrounding exterior coat about the core comprising a material ...


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Eugene J Meierhoefer: Syringe. Warner Lambert Company, Albert H Graddis, Frank S Chow, George M Yahwak, November 2, 1976: US03989044 (54 worldwide citation)

A prefilled syringe having a barrel to hold a liquid medium is disclosed. The rear end of the barrel is sealed by means of a rubber diaphragm whereas the front end of the syringe is sealed by a stopper and a novel needle hub assembly whereby the integrity of the liquid medium remains static until th ...


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Walter F Mangel, Stephen Leytus, L Lee Melhado: Rhodamine derivatives as fluorogenic substrates for proteinases. University Patents, George M Yahwak, December 10, 1985: US04557862 (54 worldwide citation)

The present invention relates to a new class of novel Rhodamine derivatives. These derivatives which are bisamide substitution products are nonfluorescent. Whereas the monoamide substitution products exhibit high fluorescence. Cleavage of a single specified amide bond by bond-specific proteinases wi ...


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Frederick L Parsons: Contact lens capsule. Warner Lambert Company, Albert H Graddis, Frank S Chow, George M Yahwak, March 15, 1977: US04011941 (49 worldwide citation)

An apparatus comprising a sterilizing capsule for the sterilizing of soft contact lenses in an aqueous hydrogen peroxide solution is disclosed.