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Andreas G Weichert
Heinz Werner Kleemann, Hans Jochen Lang, Jan Robert Schwark, Andreas Weichert, Wolfgang Scholz, Udo Albus: Substituted N-heteroaroylguanidines, a process for their preparation, their use as a medicament or diagnostic agent, and a medicament containing them. Hoechst Aktiengesellschaft, Finnegan Henderson Farabow Garrett & Dunner L, December 16, 1997: US05698581 (27 worldwide citation)

The invention relates to heteroaroylguanidines of the formula I ##STR1## in which the substituents HA and R(1) to R(5) have the meanings given in the specification. These compounds exhibit very good antiarrhythmic properties and are outstandingly suitable for use as antiarrhythmic pharmaceuticals po ...


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Andreas G Weichert
Andreas Weichert, Heinz Werner Kleemann, Hans Jochen Lang, Jan Robert Schwark, Udo Albus, Wolfgang Scholz: Substituted 1-oxo-1,2-dihydroisoquinolinoylguanidines and 1,1-dioxo-2H-1,2-benzothiazinoylguanidines, a process for their preparation, their use as medicaments or diagnostic agents, and medicaments containing them. Hoechst Aktiengesellschaft, Finnegan Henderson Farabow Garrett & Dunner L, August 20, 1996: US05547953 (15 worldwide citation)

Substituted 1-oxo-1,2-dihydroisoquinolinoylguanidines and 1,1-dioxo-2H-1,2-benzothiazinoylguanidines, a process for their preparation, their use as medicament or diagnostic agent, and also a medicament containing them. Acylguanidines I ##STR1## with X equal to carbonyl or sulfonyl; R(1) equal to H, ...


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Andreas G Weichert
Jan Robert Schwark, Joachim Brendel, Heinz Werner Kleemann, Hans Jochen Lang, Andreas Weichert, Hans Willi Jansen, Wolfgang Scholz: Phenyl-substituted alkenylcarboxylic acid guanidides, process for their preparation, their use as a medicament or diagnostic, and medicament containing them. Hoechst Aktiengesellschaft, Finnegan Henderson Farabow Garrett & Dunner L, December 21, 1999: US06005010 (8 worldwide citation)

Compounds of the formula ##STR1## where T is ##STR2## and R(A), R(B), R(C), R(D), R(E), R(F), x and y have the meanings indicated in the claims, and their pharmaceutically acceptable salts are effective inhibitors of the cellular sodium-proton antiporter (Na.sup.+ /H.sup.+ exchanger). These compound ...


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Andreas G Weichert
Jan Robert Schwark, Heinz Werner Kleemann, Hans Jochen Lang, Andreas Weichert, Wolfgang Scholz, Udo Albus: Phenyl-substituted alkylcarboguanidides carrying perfluoroalkyl groups, a process for their preparation, their use as a medicament or a diagnostic agent, and a medicament containing them. Hoechst Aktiengesellschaft, Finnegan Henderson Farabow Garrett & Dunner L, October 22, 1996: US05567734 (7 worldwide citation)

Phenyl-substituted alkylcarboguanidides carrying perfluoroalkyl groups, of the formula I ##STR1## are described where R(A) and R(B) are H, Hal, CN, OR(6), alkyl, O.sub.r -perfluoroalkyl or NR(7)R(8); R(6) is hydrogen, (cyclo)alk(en)yl, perfluoroalkyl, phenyl or benzyl; R(7) and R(8) are defined as R ...


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