1
Arnold I Caplan, Stephen E Haynesworth: Human mesenchymal stem cells. Osiris Therapeutics, Charles J Herron, Elliot M Olstein, January 23, 1996: US05486359 (515 worldwide citation)

Isolated human mesenchymal stem cells which can differentiate into more than one tissue type (e.g. bone, cartilage, muscle or marrow stroma), a method for isolating, purifying, and culturally expanding human mesenchymal stem cells (i.e. "mesenchymal stem cells" or "hMSCs"), and characterization of a ...


2
Ronald Lloyd, Brian W Walter: Tearable composite strip of materials. T J Smith & Nephew, Louis E Marn, Elliot M Olstein, January 20, 1981: US04245630 (501 worldwide citation)

A composite strip material comprising at least a backing layer, an adhesive layer on a surface thereof, and a removable protective layer over and contacting and peelably adherent to at least part of the adhesive layer; wherein each layer is finger-tearable and wherein at least one layer is cleanly f ...


3
W French Anderson, R Michael Blaese, Steven A Rosenberg: Gene therapy. The United States of America represented by the Department of Health and Human Services, Elliot M Olstein, Raymond J Lillie, March 21, 1995: US05399346 (479 worldwide citation)

Primary human cells which are genetically engineered with DNA (RNA) encoding a marker or therapeutic which is expressed to be expressed in vivo. Such engineered cells may be used in gene therapy.


4
Robert L Campbell, Daniel B Wagner, James P O Connell: Solid phase assay with visual readout. Becton Dickinson and Company, Elliot M Olstein, October 27, 1987: US04703017 (321 worldwide citation)

Solid phase assay for an analyte wherein binder is supported on a solid support, such as nitrocellulose, and the tracer is comprised of ligand labeled with a colored particulate label, such as a liposome including a dye. The assay has a high sensitivity, and the tracer is visible on the support unde ...


5
Robert D Pfister: Connector. Becton Dickinson & Company, Louis E Marn, Elliot M Olstein, June 15, 1982: US04334551 (273 worldwide citation)

A reusable connector which is provided with a deformable barrier at the open connecting end thereof which maintains the sterile integrity of the interior portions. The deformable barrier includes a preformed opening (or openings) which is normally closed and which can be opened by application of a d ...


6
Arnold I Caplan, Stephen E Haynesworth: Connective tissue regeneration using human mesenchymal stem cell preparations. Osiris Therapeutics, Charles J Herron, Elliot M Olstein, September 22, 1998: US05811094 (264 worldwide citation)

Isolated human mesenchymal stem cells, a method for isolating, purifying, and culturally expanding human mesenchymal stem cells (i.e. mesenchymal stem cells or "MSCs"), and characterization of (including by cytokine expression profiling) and uses, particularly research reagent, diagnostic and therap ...


7
Pedro Gutierrez: Localizing device. Elliot M Olstein, June 3, 1986: US04592356 (221 worldwide citation)

Localizing needle having anchor-like barbs to firmly anchor the needle in skin or tissue so as to aid in location of lesions.


8
Victor M Goldberg, Arnold I Caplan, Francis P Barry, David J Fink, Daniel R Marshak, James S Burns: Osteoarthritis cartilage regeneration. Osiris Therapeutics, Elliot M Olstein, Raymond J Lillie, December 28, 2004: US06835377 (194 worldwide citation)

For repair of cartilage damaged as part of the degenerative effects of osteoarthritis, the inventors have found that the human mesenchymal stem cell approach makes it possible to: (1) regenerate both shallow cartilage chondral defects and full thickness cartilage defects (osteochondral lesions); (2) ...


9
Stanton L Gerson, Arnold I Caplan, Stephen E Haynesworth: Transduced mesenchymal stem cells. Case Western Reserve University, Charles J Herron, Elliot M Olstein, January 7, 1997: US05591625 (174 worldwide citation)

Genetically engineered human stem cells that carry within them genes of interest particularly for the expression of physiologically or pharmacologically active proteins or for use in gene therapy. In addition to correction of genetic disorders, is the ability to introduce, in a targeted manner, addi ...


10
Robert W Rosenstein, Timothy G Bloomster: Solid phase assay employing capillary flow. Becton Dickinson and Company, Elliot M Olstein, John G Gilfillan III, John N Bain, August 8, 1989: US04855240 (174 worldwide citation)

Test device and assay for determining analyte wherein tracer and sample may be simultaneously applied to different absorbent material portions both in capillary flow communication with an absorbent material portion having a binder supported thereon in a manner whereby sample contacts binder, prior t ...